Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan, HAM Gomaa, ... Polymers 15 (5), 1123, 2023 | 73 | 2023 |
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity FAM Mohamed, HAM Gomaa, OM Hendawy, AT Ali, HS Farghaly, ... Bioorganic Chemistry 112, 104960, 2021 | 55 | 2021 |
5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents BGM Youssif, AM Mohamed, EEA Osman, OF Abou-Ghadir, DH Elnaggar, ... European Journal of Medicinal Chemistry 177, 1-11, 2019 | 51 | 2019 |
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1, 3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac … SA Abdel-Aziz, ES Taher, P Lan, GF Asaad, HAM Gomaa, NA El-Koussi, ... Bioorganic Chemistry 111, 104890, 2021 | 50 | 2021 |
Novel aryl carboximidamide and 3-aryl-1, 2, 4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies BGM Youssif, MFA Mohamed, MM Al-Sanea, AH Moustafa, ... Bioorganic chemistry 85, 577-584, 2019 | 50 | 2019 |
Design, synthesis, and antibacterial evaluation of new quinoline-1, 3, 4-oxadiazole and quinoline-1, 2, 4-triazole hybrids as potential inhibitors of DNA gyrase and … HA Hofny, MFA Mohamed, HAM Gomaa, SA Abdel-Aziz, BGM Youssif, ... Bioorganic Chemistry 112, 104920, 2021 | 45 | 2021 |
Optimization and SAR investigation of novel 2, 3-dihydropyrazino [1, 2-a] indole-1, 4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and … HAM Gomaa, ME Shaker, SI Alzarea, OM Hendawy, FAM Mohamed, ... Bioorganic Chemistry 120, 105616, 2022 | 42 | 2022 |
Novel 1, 2, 4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity HAM Gomaa, HAM El-Sherief, S Hussein, AM Gouda, OIA Salem, ... Bioorganic chemistry 105, 104369, 2020 | 40 | 2020 |
Design and synthesis of new triarylimidazole derivatives as dual inhibitors of BRAF V600E /p38 αwith potential antiproliferative activity AAM Bahaa G.M. Youssif , Ahmed M. Gouda , Amr H. Moustafa , Antar A ... Journal of Molecular Structure 1253, 132218, 2021 | 39* | 2021 |
Design, synthesis and biological evaluation of new HDAC1 and HDAC2 inhibitors endowed with ligustrazine as a novel cap moiety MM Al-Sanea, L Gotina, MFA Mohamed, D Grace Thomas Parambi, ... Drug design, development and therapy, 497-508, 2020 | 38 | 2020 |
Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies RA Mekheimer, SMR Allam, MA Al-Sheikh, MS Moustafa, SM Al-Mousawi, ... Bioorganic Chemistry 121, 105693, 2022 | 34 | 2022 |
New 1, 3, 4‐oxadiazoles linked with the 1, 2, 3‐triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase MA Mahmoud, AF Mohammed, OIA Salem, HAM Gomaa, BGM Youssif Archiv der Pharmazie 355 (6), 2200009, 2022 | 32 | 2022 |
Design, synthesis, and antibacterial screening of some novel heteroaryl-based ciprofloxacin derivatives as DNA gyrase and topoisomerase IV inhibitors LH Al-Wahaibi, AA Amer, AA Marzouk, HAM Gomaa, BGM Youssif, ... Pharmaceuticals 14 (5), 399, 2021 | 31 | 2021 |
Structure-based design, synthesis and antiproliferative action of new quinazoline-4-one/chalcone hybrids as EGFR inhibitors M Hisham, HA Hassan, HAM Gomaa, BGM Youssif, AM Hayallah, ... Journal of Molecular Structure 1254, 132422, 2022 | 28 | 2022 |
New quinoline/1, 2, 4-triazole hybrids as dual inhibitors of COX-2/5-LOX and inflammatory cytokines: Design, synthesis, and docking study AM Mohassab, HA Hassan, D Abdelhamid, AM Gouda, HAM Gomaa, ... Journal of Molecular Structure 1244, 130948, 2021 | 21 | 2021 |
Assessment of the chemo-preventive effects of various plant constituents against doxorubicin-induced toxicity in rats HA Soliman, RR Ahmed, HA Gomaa, AT Ali Journal of American Science 10 (9), 153-64, 2014 | 19 | 2014 |
Novel 1, 2, 4-oxadiazole/pyrrolidine hybrids as DNA gyrase and topoisomerase IV inhibitors with potential antibacterial activity FOA Frejat, Y Cao, H Zhai, SA Abdel-Aziz, HAM Gomaa, BGM Youssif, ... Arabian Journal of Chemistry 15 (1), 103538, 2022 | 18 | 2022 |
Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease O Hendawy, HAM Gomaa, S Hussein, SI Alzarea, S Qasim, ... Saudi Pharmaceutical Journal 29 (11), 1303-1313, 2021 | 18 | 2021 |
Novel 1, 5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects OM Hendawy, HAM Gomaa, SI Alzarea, MS Alshammari, FAM Mohamed, ... Bioorganic Chemistry 116, 105302, 2021 | 16 | 2021 |
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties HA Abou‐Zied, EAM Beshr, HAM Gomaa, YA Mostafa, BGM Youssif, ... Archiv der Pharmazie 356 (4), 2200464, 2023 | 13 | 2023 |