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Melissa Gray
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Targeted glycan degradation potentiates the anticancer immune response in vivo
MA Gray, MA Stanczak, NR Mantuano, H Xiao, JFA Pijnenborg, ...
Nature Chemical Biology 16 (12), 1376-1384, 2020
2602020
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
ST Wang, MA Gray, S Xuan, Y Lin, J Byrnes, AI Nguyen, N Todorova, ...
Proceedings of the National Academy of Sciences 117 (12), 6339-6348, 2020
1142020
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
S Wisnovsky, L Möckl, SA Malaker, K Pedram, GT Hess, NM Riley, ...
Proceedings of the National Academy of Sciences 118 (5), e2015024118, 2021
932021
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
MA Stanczak, N Rodrigues Mantuano, N Kirchhammer, DE Sanin, ...
Science Translational Medicine 14 (669), eabj1270, 2022
852022
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells
B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ...
Molecular cell 78 (5), 824-834. e15, 2020
832020
CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity
CK Tsui, RM Barfield, CR Fischer, DW Morgens, A Li, BAH Smith, ...
Nature chemical biology 15 (10), 949-958, 2019
662019
Engineering orthogonal polypeptide GalNAc-transferase and UDP-sugar pairs
J Choi, LJS Wagner, SBPE Timmermans, SA Malaker, B Schumann, ...
Journal of the American Chemical Society 141 (34), 13442-13453, 2019
612019
A nanobody activation immunotherapeutic that selectively destroys HER2‐positive breast cancer cells
MA Gray, RN Tao, SM DePorter, DA Spiegel, BR McNaughton
Chembiochem 17 (2), 155-158, 2016
602016
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth
E Scott, K Hodgson, B Calle, H Turner, K Cheung, A Bermudez, ...
Oncogene 42 (12), 926-937, 2023
212023
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
P Bule, L Chuzel, E Blagova, L Wu, MA Gray, B Henrissat, E Rapp, ...
Nature Communications 10 (1), 4816, 2019
192019
Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE
C Tsai, K Mukai, PV Robinson, MA Gray, MB Waschmann, SC Lyu, M Tsai, ...
Journal of Allergy and Clinical Immunology 141 (5), 1901-1904. e15, 2018
152018
Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer
PA Szijj, MA Gray, MK Ribi, C Bahou, JCF Nogueira, CR Bertozzi, ...
Nature Chemistry, 1-12, 2023
92023
Antibody-lectin chimeras for glyco-immune checkpoint blockade
JC Stark, MA Gray, S Wisnovsky, I Ibarlucea-Benitez, NM Riley, MK Ribi, ...
BioRxiv, 2022.10. 26.513931, 2022
92022
Targeted desialylation overcomes glyco-immune checkpoints and potentiates the anticancer immune response in vivo
MA Gray, MA Stanczak, H Xiao, JFA Pijnenborg, NR Mantuano, ...
ChemRxiv 8187146, v2, 2019
92019
Mutagenesis modulates the uptake efficiency, cell-selectivity, and functional enzyme delivery of a protein transduction domain
SM DePorter, I Lui, VJ Bruce, MA Gray, M Lopez-Islas, BR McNaughton
Molecular bioSystems 10 (1), 18-23, 2014
92014
Chemical precision glyco-mutagenesis by glycosyltransferase engineering in living cells
B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ...
BioRxiv, 669861, 2019
42019
Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity
MJ Hollander, SA Malaker, NM Riley, I Perez, NM Abney, MA Gray, ...
Journal of Biological Chemistry 299 (6), 2023
12023
Conjugates for targeted cell surface editing
EC Woods, H Xiao, CR Bertozzi, M Gray
US Patent 11,459,398, 2022
12022
A one-pot synthesis of micron-sized and nanoscale poly (N-acryloxysuccinimide-co-N-vinylpyrrolidone) particles
SM DePorter, NK Hendricks, MA Gray, BR McNaughton
Tetrahedron Letters 53 (47), 6436-6438, 2012
12012
Genome-Wide CRISPR screens reveal specific ligands for glycan-binding immune checkpoint receptors
S Wisnovsky, L Mockl, SA Malaker, K Pedram, GT Hess, NM Riley, ...
GLYCOBIOLOGY 31 (12), 1682-1683, 2021
2021
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