Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1 Z Lin, L Jiang, C Yuan, JK Jensen, X Zhang, Z Luo, BC Furie, B Furie, ... Journal of Biological Chemistry 286 (9), 7027-7032, 2011 | 74 | 2011 |
A structural mechanism of flavonoids in inhibiting serine proteases G Xue, L Gong, C Yuan, M Xu, X Wang, L Jiang, M Huang Food & function 8 (7), 2437-2443, 2017 | 63 | 2017 |
6-Substituted hexamethylene amiloride (HMA) derivatives as potent and selective inhibitors of the human urokinase plasminogen activator for use in cancer BJ Buckley, A Aboelela, E Minaei, LX Jiang, Z Xu, U Ali, K Fildes, ... Journal of medicinal chemistry 61 (18), 8299-8320, 2018 | 62 | 2018 |
The crystal structure of the fifth scavenger receptor cysteine-rich domain of porcine CD163 reveals an important residue involved in porcine reproductive and respiratory … H Ma, L Jiang, S Qiao, Y Zhi, XX Chen, Y Yang, X Huang, M Huang, R Li, ... Journal of Virology 91 (3), 10.1128/jvi. 01897-16, 2017 | 54 | 2017 |
Structural basis for therapeutic intervention of uPA/uPAR system J Chi Ki Ngo, L Jiang, Z Lin, C Yuan, Z Chen, X Zhang, H Yu, J Wang, ... Current drug targets 12 (12), 1729-1743, 2011 | 50 | 2011 |
New insight into molecular interaction of heavy metal pollutant—cadmium (II) with human serum albumin Y Liu, M Chen, L Jiang, L Song Environmental Science and Pollution Research 21, 6994-7005, 2014 | 46 | 2014 |
Imaging in photodynamic therapy MR Hamblin, Y Huang CRC Press, 2017 | 36 | 2017 |
Smart photosensitizer: tumor-triggered oncotherapy by self-assembly photodynamic nanodots Y Jia, J Li, J Chen, P Hu, L Jiang, X Chen, M Huang, Z Chen, P Xu ACS applied materials & interfaces 10 (18), 15369-15380, 2018 | 35 | 2018 |
Improved therapeutic efficacy of quercetin-loaded polymeric nanoparticles on triple-negative breast cancer by inhibiting uPA Y Zhou, D Chen, G Xue, S Yu, C Yuan, M Huang, L Jiang RSC advances 10 (57), 34517-34526, 2020 | 34 | 2020 |
Serum levels of soluble platelet endothelial cell adhesion molecule 1 in COVID-19 patients are associated with disease severity L Li, M Huang, J Shen, Y Wang, R Wang, C Yuan, L Jiang, M Huang The Journal of infectious diseases 223 (1), 178-179, 2021 | 32 | 2021 |
Plasma levels of the active form of suPAR are associated with COVID-19 severity M Huang, L Li, J Shen, Y Wang, R Wang, C Yuan, M Huang, L Jiang Critical Care 24, 1-3, 2020 | 31 | 2020 |
Structural basis of covalent inhibitory mechanism of TMPRSS2-related serine proteases by camostat G Sun, Y Sui, Y Zhou, J Ya, C Yuan, L Jiang, M Huang Journal of Virology, JVI. 00861-21, 2021 | 30 | 2021 |
Rezymogenation of active urokinase induced by an inhibitory antibody L Jiang, KA Botkjaer, LM Andersen, C Yuan, PA Andreasen, M Huang Biochemical Journal 449 (1), 161-166, 2013 | 28 | 2013 |
Development of inhibitors for uPAR: blocking the interaction of uPAR with its partners C Yuan, Z Guo, S Yu, L Jiang, M Huang Drug discovery today 26 (4), 1076-1085, 2021 | 25 | 2021 |
Dissociation of zinc phthalocyanine aggregation on bacterial surface is key for photodynamic antimicrobial effect D Liu, L Li, J Chen, Z Chen, L Jiang, C Yuan, M Huang Journal of Porphyrins and Phthalocyanines 22 (09n10), 925-934, 2018 | 25 | 2018 |
Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs M Hosseini, L Jiang, HP Sørensen, JK Jensen, A Christensen, S Fogh, ... Molecular Pharmacology 80 (4), 585-597, 2011 | 24 | 2011 |
Dimer conformation of soluble PECAM-1, an endothelial marker L Jiang, L Lin, R Li, C Yuan, M Xu, JH Huang, M Huang The international journal of biochemistry & cell biology 77, 102-108, 2016 | 22 | 2016 |
6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease BJ Buckley, H Majed, A Aboelela, E Minaei, L Jiang, K Fildes, CY Cheung, ... Bioorganic & medicinal chemistry letters 29 (24), 126753, 2019 | 21 | 2019 |
The binding mechanism of a peptidic cyclic serine protease inhibitor L Jiang, ASP Svane, HP Sørensen, JK Jensen, M Hosseini, Z Chen, ... Journal of molecular biology 412 (2), 235-250, 2011 | 21 | 2011 |
Design of specific serine protease inhibitors based on a versatile peptide scaffold: conversion of a urokinase inhibitor to a plasma kallikrein inhibitor P Xu, M Xu, L Jiang, Q Yang, Z Luo, Z Dauter, M Huang, PA Andreasen Journal of medicinal chemistry 58 (22), 8868-8876, 2015 | 20 | 2015 |