Construction and immunological characterization of a novel nontoxic protective pneumolysin mutant for use in future pneumococcal vaccines LAS Kirkham, AR Kerr, GR Douce, GK Paterson, DA Dilts, DF Liu, ... Infection and immunity 74 (1), 586-593, 2006 | 134 | 2006 |
Neutrophil extracellular traps and bacterial biofilms in middle ear effusion of children with recurrent acute otitis media–a potential treatment target RB Thornton, SP Wiertsema, LAS Kirkham, PJ Rigby, S Vijayasekaran, ... PLoS One 8 (2), e53837, 2013 | 128 | 2013 |
Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+ 0 pneumococcal conjugate vaccine schedule SP Wiertsema, LAS Kirkham, KJ Corscadden, EN Mowe, JM Bowman, ... Vaccine 29 (32), 5163-5170, 2011 | 119 | 2011 |
Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin LAS Kirkham, JMC Jefferies, AR Kerr, Y Jing, SC Clarke, A Smith, ... Journal of clinical microbiology 44 (1), 151-159, 2006 | 118 | 2006 |
Presence of Nonhemolytic Pneumolysin in Serotypes of Streptococcus pneumoniae Associated with Disease Outbreaks JMC Jefferies, CHG Johnston, LAS Kirkham, GJM Cowan, KS Ross, ... Journal of Infectious Diseases 196 (6), 936-944, 2007 | 115 | 2007 |
Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children MU Bhuiyan, CC Blyth, R West, J Lang, T Rahman, C Granland, C de Gier, ... BMC pulmonary medicine 19, 1-9, 2019 | 105 | 2019 |
Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays MJ Binks, B Temple, LA Kirkham, SP Wiertsema, EM Dunne, ... PloS one 7 (3), e34083, 2012 | 104 | 2012 |
Understanding the aetiology and resolution of chronic otitis media from animal and human studies MF Bhutta, RB Thornton, LAS Kirkham, JE Kerschner, MT Cheeseman Disease models & mechanisms 10 (11), 1289-1300, 2017 | 100 | 2017 |
High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear of children with a history of recurrent acute otitis media SP Wiertsema, GR Chidlow, LAS Kirkham, KJ Corscadden, EN Mowe, ... Journal of medical virology 83 (11), 2008-2017, 2011 | 87 | 2011 |
Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts AR Kerr, LAS Kirkham, A Kadioglu, PW Andrew, P Garside, H Thompson, ... Microbes and Infection 7 (5-6), 845-852, 2005 | 84 | 2005 |
The contribution of viruses and bacteria to community-acquired pneumonia in vaccinated children: a case–control study MU Bhuiyan, TL Snelling, R West, J Lang, T Rahman, C Granland, ... Thorax 74 (3), 261-269, 2019 | 80 | 2019 |
Trivalent influenza vaccine and febrile adverse events in Australia, 2010: clinical features and potential mechanisms CC Blyth, AJ Currie, SP Wiertsema, N Conway, LAS Kirkham, A Fuery, ... Vaccine 29 (32), 5107-5113, 2011 | 68 | 2011 |
Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen EP Price, DS Sarovich, E Nosworthy, J Beissbarth, RL Marsh, J Pickering, ... BMC genomics 16, 1-10, 2015 | 63 | 2015 |
Identification of a Secreted Cholesterol-Dependent Cytolysin (Mitilysin) from Streptococcus mitis J Jefferies, L Nieminen, LA Kirkham, C Johnston, A Smith, TJ Mitchell Journal of bacteriology 189 (2), 627-632, 2007 | 48 | 2007 |
Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: a randomized controlled trial of 10-valent and 13-valent pneumococcal conjugate vaccine … WS Pomat, AHJ Van Den Biggelaar, S Wana, JP Francis, V Solomon, ... Clinical Infectious Diseases 68 (9), 1472-1481, 2019 | 42 | 2019 |
Mutant pneumolysin proteins LAS Kirkham, TJ Mitchell US Patent 7,820,789, 2010 | 42 | 2010 |
Role of viral and bacterial pathogens in causing pneumonia among Western Australian children: a case–control study protocol MU Bhuiyan, TL Snelling, R West, J Lang, T Rahman, ML Borland, ... BMJ open 8 (3), e020646, 2018 | 37 | 2018 |
Nasopharyngeal Carriage of Haemophilus haemolyticus in Otitis-Prone and Healthy Children LAS Kirkham, SP Wiertsema, EN Mowe, JM Bowman, TV Riley, ... Journal of clinical microbiology 48 (7), 2557-2559, 2010 | 37 | 2010 |
Chronic HIV-1 infection induces B-cell dysfunction that is incompletely resolved by long-term antiretroviral therapy LN Abudulai, S Fernandez, K Corscadden, M Hunter, LAS Kirkham, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 71 (4), 381-389, 2016 | 36 | 2016 |
Haemophilus haemolyticus Interaction with Host Cells Is Different to Nontypeable Haemophilus influenzae and Prevents NTHi Association with Epithelial Cells JL Pickering, A Prosser, KJ Corscadden, C De Gier, PC Richmond, ... Frontiers in cellular and infection microbiology 6, 50, 2016 | 35 | 2016 |