Fergal J. O'Brien

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Daniel KellyTrinity Centre for Biomedical Engineering, School of Engineering, Trinity College DublinVerified email at tcd.ie
Garry P. DuffyProfessor,University of GalwayVerified email at nuigalway.ie
Caroline CurtinDepartment of Anatomy, Royal College of Surgeons in Ireland, Dublin 2Verified email at rcsi.ie
Prof. Sally-Ann CryanRoyal College of Surgeons in IrelandVerified email at rcsi.ie
Tanya LevingstoneAssociate Professor, School of Mechanical and Manufacturing Engineering , Dublin City UniversityVerified email at dcu.ie
Brenton CavanaghRoyal College of Surgeons in IrelandVerified email at rcsi.ie
Eric FarrellAssociate Professor, Group Leader, Erasmus MCVerified email at erasmusmc.nl
Cathal J. KearneyDepartment of Biomedical Engineering, UMass Amherst; Royal College of Surgeons in IrelandVerified email at umass.edu
Matthew G. HaughVerified email at stanford.edu
Rosanne RafteryiEd Hub & Department of Anatomy and Neuroscience, University College CorkVerified email at ucc.ie
Oran D KennedyRoyal College of Surgeons in IrelandVerified email at rcsi.ie
Rukmani SridharanPhD student, Royal College of Surgeons in IrelandVerified email at rcsi.ie
Conor Timothy BuckleyProfessor In Biomedical Engineering, Trinity College DublinVerified email at tcd.ie
Prof. Michael B KeoghRCSIVerified email at rcsi-mub.com
Irene Mencía CastañoPhDVerified email at rcsi.ie
alan hibbittsRoyal College of Surgeons in IrelandVerified email at rcsi.ie
Arlyng González Vázquez, PhDHonorary Lecturer & Principal Investigator at TERG RCSI University of Medicine and Health Sciences.Verified email at rcsi.ie
Ioannis V. YannasProfessor of Polymer Science, Massachusetts Institute of TechnologyVerified email at mit.edu
Erica TierneyVerified email at bu.edu
Steven W. KerriganProfessor of Precision Therapeutics, RCSI University of Medicine andVerified email at rcsi.ie

Fergal J. O'Brien

Royal College of Surgeons in Ireland & AMBER Centre

Verified email at rcsi.ie - Homepage

Biomaterials mechanobiology tissue engineering gene delivery stem cells


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Biomaterials & scaffolds for tissue engineering FJ O'brien Materials today 14 (3), 88-95, 2011	4389	2011
The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering CM Murphy, MG Haugh, FJ O'brien Biomaterials 31 (3), 461-466, 2010	2254	2010
The effect of pore size on cell adhesion in collagen-GAG scaffolds FJ O’Brien, BA Harley, IV Yannas, LJ Gibson Biomaterials 26 (4), 433-441, 2005	1635	2005
Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds FJ O’Brien, BA Harley, IV Yannas, L Gibson Biomaterials 25 (6), 1077-1086, 2004	936	2004
Biomaterial based modulation of macrophage polarization: a review and suggested design principles R Sridharan, AR Cameron, DJ Kelly, CJ Kearney, FJ O’Brien Materials Today 18 (6), 313-325, 2015	858	2015
Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds CM Murphy, FJ O’Brien Cell adhesion & migration 4 (3), 377-381, 2010	662	2010
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering FJ O'Brien, BA Harley, MA Waller, IV Yannas, LJ Gibson, PJ Prendergast Technology and Health Care 15 (1), 3-17, 2007	452	2007
Staphylococcal osteomyelitis: disease progression, treatment challenges, and future directions N Kavanagh, EJ Ryan, A Widaa, G Sexton, J Fennell, S O'Rourke, ... Clinical microbiology reviews 31 (2), 10.1128/cmr. 00084-17, 2018	414	2018
Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds MG Haugh, CM Murphy, RC McKiernan, C Altenbuchner, FJ O'Brien Tissue Engineering Part A 17 (9-10), 1201-1208, 2011	360	2011
Cell-scaffold interactions in the bone tissue engineering triad. CM Murphy, F O'Brien, DG Little, A Schindeler Royal College of Surgeons in Ireland, 2013	357	2013
The effect of dehydrothermal treatment on the mechanical and structural properties of collagen‐GAG scaffolds MG Haugh, MJ Jaasma, FJ O'Brien Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2009	349	2009
Material stiffness influences the polarization state, function and migration mode of macrophages R Sridharan, B Cavanagh, AR Cameron, DJ Kelly, FJ O'Brien Acta biomaterialia 89, 47-59, 2019	332	2019
Mesenchymal stem cell fate is regulated by the composition and mechanical properties of collagen–glycosaminoglycan scaffolds CM Murphy, A Matsiko, MG Haugh, JP Gleeson, FJ O’Brien Journal of the mechanical behavior of biomedical materials 11, 53-62, 2012	324	2012
Novel freeze-drying methods to produce a range of collagen–glycosaminoglycan scaffolds with tailored mean pore sizes MG Haugh, CM Murphy, FJ O'Brien Tissue Engineering Part C: Methods 16 (5), 887-894, 2010	315	2010
Scaffold mean pore size influences mesenchymal stem cell chondrogenic differentiation and matrix deposition A Matsiko, JP Gleeson, FJ O'Brien Tissue Engineering Part A 21 (3-4), 486-497, 2015	306	2015
Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagen-based scaffold for bone tissue regeneration JP Gleeson, NA Plunkett, FJ O’Brien Eur Cell Mater 20 (218), 30, 2010	303	2010
A biomimetic multi-layered collagen-based scaffold for osteochondral repair TJ Levingstone, A Matsiko, GR Dickson, FJ O’Brien, JP Gleeson Acta biomaterialia 10 (5), 1996-2004, 2014	296	2014
The effect of bone microstructure on the initiation and growth of microcracks FJ O’Brien, D Taylor, TC Lee Journal of Orthopaedic Research 23 (2), 475-480, 2005	278	2005
A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along osteogenic and chondrogenic routes E Farrell, FJ O'Brien, P Doyle, J Fischer, I Yannas, BA Harley, B O'Connell, ... Tissue engineering 12 (3), 459-468, 2006	272	2006
The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering CM Tierney, MG Haugh, J Liedl, F Mulcahy, B Hayes, FJ O’Brien Journal of the mechanical behavior of biomedical materials 2 (2), 202-209, 2009	267	2009

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