Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9 F Bubeck, MD Hoffmann, Z Harteveld, S Aschenbrenner, A Bietz, ... Nature methods 15 (11), 924-927, 2018 | 203 | 2018 |
Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins MD Hoffmann, S Aschenbrenner, S Grosse, K Rapti, C Domenger, ... Nucleic acids research 47 (13), e75-e75, 2019 | 98 | 2019 |
Relevance of assembly-activating protein for adeno-associated virus vector production and capsid protein stability in mammalian and insect cells S Grosse, M Penaud-Budloo, AK Herrmann, K Börner, J Fakhiri, V Laketa, ... Journal of virology 91 (20), 10.1128/jvi. 01198-17, 2017 | 84 | 2017 |
Pre-arrayed pan-AAV peptide display libraries for rapid single-round screening K Börner, E Kienle, LY Huang, J Weinmann, A Sacher, P Bayer, C Stüllein, ... Molecular therapy 28 (4), 1016-1032, 2020 | 61 | 2020 |
Fantastic AAV gene therapy vectors and how to find them—random diversification, rational design and machine learning J Becker, J Fakhiri, D Grimm Pathogens 11 (7), 756, 2022 | 54 | 2022 |
Novel chimeric gene therapy vectors based on adeno-associated virus and four different mammalian bocaviruses J Fakhiri, MA Schneider, J Puschhof, M Stanifer, V Schildgen, ... Molecular Therapy-Methods & Clinical Development 12, 202-222, 2019 | 51 | 2019 |
Ex vivo/in vivo gene editing in hepatocytes using “all-in-one” CRISPR-adeno-associated virus vectors with a self-linearizing repair template SA Krooss, Z Dai, F Schmidt, A Rovai, J Fakhiri, A Dhingra, Q Yuan, ... Iscience 23 (1), 2020 | 45 | 2020 |
Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders J El Andari, E Renaud-Gabardos, W Tulalamba, J Weinmann, L Mangin, ... Science advances 8 (38), eabn4704, 2022 | 37 | 2022 |
Best of most possible worlds: Hybrid gene therapy vectors based on parvoviruses and heterologous viruses J Fakhiri, D Grimm Molecular Therapy 29 (12), 3359-3382, 2021 | 18 | 2021 |
Rapid and simple screening of CRISPR guide RNAs (gRNAs) in cultured cells using adeno-associated viral (AAV) vectors J Fakhiri, M Nickl, D Grimm CRISPR Gene Editing: Methods and Protocols, 111-126, 2019 | 15 | 2019 |
Breaking the sound barrier: Towards next-generation AAV vectors for gene therapy of hearing disorders J Fakhiri, LD Landegger, D Grimm Hearing Research 413, 108092, 2022 | 12 | 2022 |
Impact of natural or synthetic singletons in the capsid of human bocavirus 1 on particle infectivity and immunoreactivity J Fakhiri, KP Linse, M Mietzsch, M Xu, MA Schneider, M Meister, ... Journal of Virology 94 (11), 10.1128/jvi. 00170-20, 2020 | 10 | 2020 |
Severe human bocavirus 1 respiratory tract infection in an immunodeficient child with fatal outcome J Tabatabai, J Fakhiri, J Meyburg, KP Linse, M Xu, M Söderlund-Venermo, ... The Pediatric Infectious Disease Journal 38 (9), e219-e222, 2019 | 10 | 2019 |
Characterization of the GBoV1 capsid and its antibody interactions JC Yu, M Mietzsch, A Singh, A Jimenez Ybargollin, S Kailasan, ... Viruses 13 (2), 330, 2021 | 6 | 2021 |
Means and methods for inactivating therapeutic dna in a cell D Grimm, J Fakhiri US Patent App. 16/094,788, 2019 | 4 | 2019 |
254. New Chimeric Gene Therapy Vectors Based on Four Different Mammalian Bocaviruses J Fakhiri, M Schneider, S Kailasan, M Meister, MA McKenna, Z Yan, J Qiu, ... Molecular Therapy 24, S100, 2016 | 4 | 2016 |
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control U Wessels, F Neff, J Fakhiri, K Mayer, U Brinkmann, K Stubenrauch Bioanalysis, 2024 | | 2024 |
Peptide-displaying chimeric AAV vectors with increased skeletal muscle potency and liver detargeting for systemic gene therapy E Renaud-Gabardos, J El Andari, L Mangin, J Weinmann, E Attebi, ... Myology 2022, 2022 | | 2022 |
Efficient Crossing of the Primate Bloodbrain Barrier by Adeno-Associated Virus Serotype 4 (AAV4) O Maiakovska, JL Guo, F Bubeck, M Tiffany, J Becker, G Huber, ... MOLECULAR THERAPY 30 (4), 242-242, 2022 | | 2022 |
Modulated cas-inhibitors D Niopek, R Eils, F Bubeck, D Grimm, MD Hoffmann, MC Waldhauer, ... US Patent App. 16/756,887, 2021 | | 2021 |