Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia M Cavazzana-Calvo, E Payen, O Negre, G Wang, K Hehir, F Fusil, ... Nature 467 (7313), 318-322, 2010 | 1635 | 2010 |
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells J Scholler, TL Brady, G Binder-Scholl, WT Hwang, G Plesa, KM Hege, ... Science translational medicine 4 (132), 132ra53-132ra53, 2012 | 777 | 2012 |
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency T Schaller, KE Ocwieja, J Rasaiyaah, AJ Price, TL Brady, SL Roth, S Hué, ... PLoS pathogens 7 (12), e1002439, 2011 | 553 | 2011 |
HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2 KE Ocwieja, TL Brady, K Ronen, A Huegel, SL Roth, T Schaller, ... PLoS pathogens 7 (3), e1001313, 2011 | 269 | 2011 |
piggyBac transposase tools for genome engineering X Li, ER Burnight, AL Cooney, N Malani, T Brady, JD Sander, J Staber, ... Proceedings of the National Academy of Sciences 110 (25), E2279-E2287, 2013 | 262 | 2013 |
HIV integration site distributions in resting and activated CD4+ T cells infected in culture T Brady, LM Agosto, N Malani, CC Berry, U O'Doherty, F Bushman Aids 23 (12), 1461-1471, 2009 | 183 | 2009 |
Directly infected resting CD4+ T cells can produce HIV Gag without spreading infection in a model of HIV latency MJ Pace, EH Graf, LM Agosto, AM Mexas, F Male, T Brady, FD Bushman, ... PLoS pathogens 8 (7), e1002818, 2012 | 167 | 2012 |
Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV P Tebas, D Stein, G Binder-Scholl, R Mukherjee, T Brady, T Rebello, ... Blood, The Journal of the American Society of Hematology 121 (9), 1524-1533, 2013 | 147 | 2013 |
Integration target site selection by a resurrected human endogenous retrovirus T Brady, YN Lee, K Ronen, N Malani, CC Berry, PD Bieniasz, ... Genes & development 23 (5), 633-642, 2009 | 129 | 2009 |
Phosphorylation regulates integration of the yeast Ty5 retrotransposon into heterochromatin J Dai, W Xie, TL Brady, J Gao, DF Voytas Molecular cell 27 (2), 289-299, 2007 | 100 | 2007 |
Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia K Ronen, O Negre, S Roth, C Colomb, N Malani, M Denaro, T Brady, ... Molecular Therapy 19 (7), 1273-1286, 2011 | 91 | 2011 |
Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains K Gupta, T Brady, BM Dyer, N Malani, Y Hwang, F Male, RT Nolte, ... Journal of Biological Chemistry 289 (30), 20477-20488, 2014 | 85 | 2014 |
A method to sequence and quantify DNA integration for monitoring outcome in gene therapy T Brady, SL Roth, N Malani, GP Wang, CC Berry, P Leboulch, ... Nucleic acids research 39 (11), e72-e72, 2011 | 81 | 2011 |
Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction L Zhong, N Malani, M Li, T Brady, J Xie, P Bell, S Li, H Jones, JM Wilson, ... Human gene therapy 24 (5), 520-525, 2013 | 52 | 2013 |
Methods for integration site distribution analyses in animal cell genomes A Ciuffi, K Ronen, T Brady, N Malani, G Wang, CC Berry, FD Bushman Methods 47 (4), 261-268, 2009 | 52 | 2009 |
Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays T Brady, BJ Kelly, F Male, S Roth, A Bailey, N Malani, R Gijsbers, ... Journal of virological methods 189 (1), 53-57, 2013 | 37 | 2013 |
Retrotransposon target site selection by imitation of a cellular protein TL Brady, PG Fuerst, RA Dick, C Schmidt, DF Voytas Molecular and cellular biology 28 (4), 1230-1239, 2008 | 28 | 2008 |
Targeting Integration of the Saccharomyces Ty5 Retrotransposon TL Brady, CL Schmidt, DF Voytas Chromosomal Mutagenesis, 153-163, 2008 | 26 | 2008 |
Nondividing cells: a safer bet for integrating vectors? T Brady, FD Bushman Molecular Therapy 19 (4), 640-641, 2011 | 9 | 2011 |
134 HIV DNA Integration: Mechanism and Consequences FD Bushman, T Brady, N Malani, P Leboulch, S Hacein-Bey, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 59, 55, 2012 | 2 | 2012 |