Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues A Leonard, A Bertero, JD Powers, KM Beussman, S Bhandari, M Regnier, ... Journal of molecular and cellular cardiology 118, 147-158, 2018 | 170 | 2018 |
Myosin filament activation in the heart is tuned to the mechanical task M Reconditi, M Caremani, F Pinzauti, JD Powers, T Narayanan, ... Proceedings of the National Academy of Sciences 114 (12), 3240-3245, 2017 | 132 | 2017 |
The sliding filament theory since Andrew Huxley: multiscale and multidisciplinary muscle research JD Powers, SA Malingen, M Regnier, TL Daniel Annual review of biophysics 50 (1), 373-400, 2021 | 50 | 2021 |
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin JD Powers, CC Yuan, KJ McCabe, JD Murray, MC Childers, GV Flint, ... Proceedings of the National Academy of Sciences 116 (23), 11502-11507, 2019 | 41 | 2019 |
Inotropic interventions do not change the resting state of myosin motors during cardiac diastole M Caremani, F Pinzauti, JD Powers, S Governali, T Narayanan, ... Journal of General Physiology 151 (1), 53-65, 2019 | 39 | 2019 |
Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle L Fusi, V Percario, E Brunello, M Caremani, P Bianco, JD Powers, ... The Journal of physiology 595 (4), 1127-1142, 2017 | 38 | 2017 |
A spatially explicit model shows how titin stiffness modulates muscle mechanics and energetics JD Powers, CD Williams, M Regnier, TL Daniel Integrative and comparative biology 58 (2), 186-193, 2018 | 29 | 2018 |
Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts JD Powers, KB Kooiker, AB Mason, AE Teitgen, GV Flint, JC Tardiff, ... JCI insight 5 (20), 2020 | 26 | 2020 |
Contracting striated muscle has a dynamic I‐band spring with an undamped stiffness 100 times larger than the passive stiffness JD Powers, P Bianco, I Pertici, M Reconditi, V Lombardi, G Piazzesi The Journal of Physiology 598 (2), 331-345, 2020 | 25 | 2020 |
The effect of variable troponin C mutation thin filament incorporation on cardiac muscle twitch contractions SM Mijailovich, M Prodanovic, C Poggesi, JD Powers, J Davis, ... Journal of molecular and cellular cardiology 155, 112-124, 2021 | 21 | 2021 |
Subcellular remodeling in filamin C deficient mouse hearts impairs myocyte tension development during progression of dilated cardiomyopathy JD Powers, NJ Kirkland, C Liu, SS Razu, X Fang, AJ Engler, J Chen, ... International journal of molecular sciences 23 (2), 871, 2022 | 11 | 2022 |
Biomechanical signals regulating the structure of the heart JD Powers, AD McCulloch Current Opinion in Physiology 25, 100482, 2022 | 10 | 2022 |
Multiscale models of cardiac muscle biophysics and tissue remodeling in hypertrophic cardiomyopathies Y Aboelkassem, JD Powers, KJ McCabe, AD McCulloch Current opinion in biomedical engineering 11, 35-44, 2019 | 10 | 2019 |
The predicted role of steric specificity in crowding-mediated effects on reversible biomolecular association JD Powers, BT Castle, DJ Odde Physical Biology 12 (6), 066004, 2015 | 6 | 2015 |
Machine learning meets Monte Carlo methods for models of muscle’s molecular machinery to classify mutations A Asencio, S Malingen, KB Kooiker, JD Powers, J Davis, T Daniel, ... Journal of General Physiology 155 (5), e202213291, 2023 | 4 | 2023 |
Modulation of calcium sensitivity and twitch contractions in cardiac muscle with troponin-C mutations: simulations and experiments SM Mijailovich, M Prodanovic, L Vasovic, B Stojanovic, M Maric, ... Biophysical Journal 116 (3), 116a, 2019 | 4 | 2019 |
Nuclear mechanosignaling in striated muscle diseases B Zhang, JD Powers, AD McCulloch, NC Chi Frontiers in Physiology 14, 1126111, 2023 | 3 | 2023 |
Cardiac‐specific Deletion of Filamin C Decouples Myocyte Contractility and Calcium Handling in Adult Mice JD Powers, C Liu, X Fang, JH Omens, J Chen, AD McCulloch The FASEB Journal 34 (S1), 1-1, 2020 | 1 | 2020 |
Influence of cTn Ca2+ binding properties and cooperative mechanisms on cardiac muscle contractile dynamics SM Mijailovich, D Nedic, B Stojanovic, JD Powers, J Davis, MA Geeves, ... Biophysical Journal 114 (3), 500a, 2018 | 1 | 2018 |
Evidence for an I-Band Spring that is Tuned to the Length of the Skeletal Muscle Sarcomere JD Powers, M Reconditi, L Fusi, E Brunello, V Lombardi, G Piazzesi Biophysical Journal 112 (3), 181a, 2017 | 1 | 2017 |