Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages KL Laugwitz, A Moretti, J Lam, P Gruber, Y Chen, S Woodard, LZ Lin, ... Nature 433 (7026), 647-653, 2005 | 1677 | 2005 |
Patient-specific induced pluripotent stem-cell models for long-QT syndrome A Moretti, M Bellin, A Welling, CB Jung, JT Lam, L Bott-Flügel, T Dorn, ... New England Journal of Medicine 363 (15), 1397-1409, 2010 | 1464 | 2010 |
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification A Moretti, L Caron, A Nakano, JT Lam, A Bernshausen, Y Chen, Y Qyang, ... Cell 127 (6), 1151-1165, 2006 | 1255 | 2006 |
Human engineered heart tissue: analysis of contractile force I Mannhardt, K Breckwoldt, D Letuffe-Brenière, S Schaaf, H Schulz, ... Stem cell reports 7 (1), 29-42, 2016 | 397 | 2016 |
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/β-catenin pathway Y Qyang, S Martin-Puig, M Chiravuri, S Chen, H Xu, L Bu, X Jiang, L Lin, ... Cell stem cell 1 (2), 165-179, 2007 | 395 | 2007 |
Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia CB Jung, A Moretti, M Mederos y Schnitzler, L Iop, U Storch, M Bellin, ... EMBO molecular medicine 4 (3), 180-191, 2012 | 374 | 2012 |
Islet1 cardiovascular progenitors: a single source for heart lineages? KL Laugwitz, A Moretti, L Caron, A Nakano, KR Chien Oxford University Press for The Company of Biologists Limited 135 (2), 193-205, 2008 | 339 | 2008 |
Embryonic heart progenitors and cardiogenesis T Brade, LS Pane, A Moretti, KR Chien, KL Laugwitz Cold Spring Harbor perspectives in medicine 3 (10), a013847, 2013 | 306 | 2013 |
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long‐QT syndrome M Bellin, S Casini, RP Davis, C D'aniello, J Haas, D Ward‐van Oostwaard, ... The EMBO journal 32 (24), 3161-3175, 2013 | 268 | 2013 |
Functional diversity of P-type and R-type calcium channels in rat cerebellar neurons A Tottene, A Moretti, D Pietrobon Journal of Neuroscience 16 (20), 6353-6363, 1996 | 222 | 1996 |
Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy A Moretti, L Fonteyne, F Giesert, P Hoppmann, AB Meier, T Bozoglu, ... Nature medicine 26 (2), 207-214, 2020 | 219 | 2020 |
Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors A Moretti, M Bellin, CB Jung, TM Thies, Y Takashima, A Bernshausen, ... The FASEB Journal 24 (3), 700-711, 2010 | 158 | 2010 |
Diabetes mellitus–induced microvascular destabilization in the myocardium R Hinkel, A Howe, S Renner, J Ng, S Lee, K Klett, V Kaczmarek, A Moretti, ... Journal of the American College of Cardiology 69 (2), 131-143, 2017 | 156 | 2017 |
Blocking caspase-activated apoptosis improves contractility in failing myocardium KL Laugwitz, A Moretti, HJ Weig, A Gillitzer, K Pinkernell, T Ott, I Pragst, ... Human gene therapy 12 (17), 2051-2063, 2001 | 143 | 2001 |
Essential myosin light chain as a target for caspase-3 in failing myocardium A Moretti, HJ Weig, T Ott, M Seyfarth, HP Holthoff, D Grewe, A Gillitzer, ... Proceedings of the National Academy of Sciences 99 (18), 11860-11865, 2002 | 140 | 2002 |
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes M Rocchetti, L Sala, L Dreizehnter, L Crotti, D Sinnecker, M Mura, ... Cardiovascular research 113 (5), 531-541, 2017 | 130 | 2017 |
Antisense‐mediated exon skipping: a therapeutic strategy for titin‐based dilated cardiomyopathy M Gramlich, LS Pane, Q Zhou, Z Chen, M Murgia, S Schötterl, A Goedel, ... EMBO molecular medicine 7 (5), 562-576, 2015 | 127 | 2015 |
Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity T Dorn, A Goedel, JT Lam, J Haas, Q Tian, F Herrmann, K Bundschu, ... Stem cells 33 (4), 1113-1129, 2015 | 117 | 2015 |
Pluripotent stem cell models of human heart disease A Moretti, KL Laugwitz, T Dorn, D Sinnecker, C Mummery Cold Spring Harbor Perspectives in Medicine 3 (11), a014027, 2013 | 113 | 2013 |
Induced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing D Sinnecker, KL Laugwitz, A Moretti Pharmacology & therapeutics 143 (2), 246-252, 2014 | 105 | 2014 |