High burden and pervasive positive selection of somatic mutations in normal human skin I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ... Science 348 (6237), 880-886, 2015 | 1784 | 2015 |
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression PH Jones, FM Watt Cell 73 (4), 713-724, 1993 | 1485 | 1993 |
Stem cell patterning and fate in human epidermis PH Jones, S Harper, FM Watt Cell 80 (1), 83-93, 1995 | 1056 | 1995 |
Clock-like mutational processes in human somatic cells LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ... Nature genetics 47 (12), 1402-1407, 2015 | 1030 | 2015 |
A single type of progenitor cell maintains normal epidermis E Clayton, DP Doupé, AM Klein, DJ Winton, BD Simons, PH Jones Nature 446 (7132), 185-189, 2007 | 1030 | 2007 |
Somatic mutant clones colonize the human esophagus with age I Martincorena, JC Fowler, A Wabik, ARJ Lawson, F Abascal, MWJ Hall, ... Science 362 (6417), 911-917, 2018 | 995 | 2018 |
Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundaries of stem-cell clusters S Lowell, P Jones, I Le Roux, J Dunne, FM Watt Current Biology 10 (9), 491-500, 2000 | 581 | 2000 |
A single progenitor population switches behavior to maintain and repair esophageal epithelium DP Doupé, MP Alcolea, A Roshan, G Zhang, AM Klein, BD Simons, ... Science 337 (6098), 1091-1093, 2012 | 341 | 2012 |
Developmental cell programs are co-opted in inflammatory skin disease G Reynolds, P Vegh, J Fletcher, EFM Poyner, E Stephenson, I Goh, ... Science 371 (6527), eaba6500, 2021 | 332 | 2021 |
The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate DP Doupé, AM Klein, BD Simons, PH Jones Developmental cell 18 (2), 317-323, 2010 | 276 | 2010 |
Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells P Jones, G May, L Healy, J Brown, G Hoyne, S Delassus, T Enver Blood, The Journal of the American Society of Hematology 92 (5), 1505-1511, 1998 | 204 | 1998 |
Sic transit gloria: farewell to the epidermal transit amplifying cell? PH Jones, BD Simons, FM Watt Cell stem cell 1 (4), 371-381, 2007 | 199 | 2007 |
Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change MP Alcolea, P Greulich, A Wabik, J Frede, BD Simons, PH Jones Nature cell biology 16 (6), 612-619, 2014 | 188 | 2014 |
Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study MR Albertella, PM Loadman, PH Jones, RM Phillips, R Rampling, ... Clinical cancer research 14 (4), 1096-1104, 2008 | 154 | 2008 |
Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells V Zecchini, R Domaschenz, D Winton, P Jones Genes & development 19 (14), 1686-1691, 2005 | 148 | 2005 |
Expression and function of the keratinocyte integrins FM Watt, PH Jones Development 119 (Supplement), 185-192, 1993 | 147 | 1993 |
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ... Nature genetics 52 (6), 604-614, 2020 | 137 | 2020 |
Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia AM Klein, DE Brash, PH Jones, BD Simons Proceedings of the National Academy of Sciences 107 (1), 270-275, 2010 | 129 | 2010 |
Mutant clones in normal epithelium outcompete and eliminate emerging tumours B Colom, A Herms, MWJ Hall, SC Dentro, C King, RK Sood, MP Alcolea, ... Nature 598, 510–514, 2021 | 126 | 2021 |
Role for amplification and expression of glypican-5 in rhabdomyosarcoma D Williamson, J Selfe, T Gordon, YJ Lu, K Pritchard-Jones, K Murai, ... Cancer research 67 (1), 57-65, 2007 | 119 | 2007 |