Development of a highly α-regioselective metal-mediated allylation reaction in aqueous media: new mechanistic proposal for the origin of α-homoallylic alcohols KT Tan, SS Chng, HS Cheng, TP Loh Journal of the American Chemical Society 125 (10), 2958-2963, 2003 | 211 | 2003 |
Environment-sensitive fluorescent turn-on probes targeting hydrophobic ligand-binding domains for selective protein detection. YD Zhuang, PY Chiang, CW Wang, KT Tan Angewandte Chemie 125 (31), 2013 | 194 | 2013 |
Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes YW Wu, LK Oesterlin, KT Tan, H Waldmann, K Alexandrov, RS Goody Nature chemical biology 6 (7), 534-540, 2010 | 145 | 2010 |
Semisynthetic fluorescent sensor proteins based on self-labeling protein tags MA Brun, KT Tan, E Nakata, MJ Hinner, K Johnsson Journal of the American Chemical Society 131 (16), 5873-5884, 2009 | 143 | 2009 |
Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators YW Wu, KT Tan, H Waldmann, RS Goody, K Alexandrov Proceedings of the National Academy of Sciences 104 (30), 12294-12299, 2007 | 127 | 2007 |
Diverse Cyclization Catalyzed by In(OTf)3 for the Convergent Assembly of Substituted Tetrahydrofurans and Tetrahydropyrans TP Loh, QY Hu, KT Tan, HS Cheng Organic Letters 3 (17), 2669-2672, 2001 | 114 | 2001 |
A semisynthetic fluorescent sensor protein for glutamate MA Brun, KT Tan, R Griss, A Kielkowska, L Reymond, K Johnsson Journal of the American Chemical Society 134 (18), 7676-7678, 2012 | 108 | 2012 |
Protein sensing in living cells by molecular rotor-based fluorescence-switchable chemical probes WT Yu, TW Wu, CL Huang, IC Chen, KT Tan Chemical science 7 (1), 301-307, 2016 | 90 | 2016 |
Selective cross-linking of interacting proteins using self-labeling tags A Gautier, E Nakata, G Lukinavicius, KT Tan, K Johnsson Journal of the American Chemical Society 131 (49), 17954-17962, 2009 | 89 | 2009 |
A selective and sensitive fluorescent albumin probe for the determination of urinary albumin YY Wu, WT Yu, TC Hou, TK Liu, CL Huang, IC Chen, KT Tan Chemical communications 50 (78), 11507-11510, 2014 | 85 | 2014 |
The lipid modifications of Ras that sense membrane environments and induce local enrichment A Vogel, G Reuther, K Weise, G Triola, J Nikolaus, KT Tan, C Nowak, ... Angewandte Chemie International Edition 48 (46), 8784-8787, 2009 | 83 | 2009 |
Semisynthesis of fluorescent metabolite sensors on cell surfaces MA Brun, R Griss, L Reymond, KT Tan, J Piguet, RJRW Peters, H Vogel, ... Journal of the American Chemical Society 133 (40), 16235-16242, 2011 | 81 | 2011 |
The First In(OTf)3 -Catalyzed Conversion of Kinetically Formed Homoallylic Alcohols into the Thermodynamically Preferred Regioisomers: Application to the … TP Loh, KT Tan, QY Hu Angewandte Chemie (International ed. in English) 40 (15), 2921-2922, 2001 | 78 | 2001 |
An unusual approach to the synthesis of enantiomerically cis linear homoallylic alcohols based on the steric interaction mechanism of camphor scaffold CLK Lee, CHA Lee, KT Tan, TP Loh Organic letters 6 (8), 1281-1283, 2004 | 75 | 2004 |
The lipidated membrane anchor of full length N-Ras protein shows an extensive dynamics as revealed by solid-state NMR spectroscopy G Reuther, KT Tan, A Vogel, C Nowak, K Arnold, J Kuhlmann, ... Journal of the American Chemical Society 128 (42), 13840-13846, 2006 | 74 | 2006 |
Flexibility of ras lipid modifications studied by 2H solid-state NMR and molecular dynamics simulations A Vogel, KT Tan, H Waldmann, SE Feller, MF Brown, D Huster Biophysical journal 93 (8), 2697-2712, 2007 | 65 | 2007 |
S-Cis Diene Conformation: A New Bathochromic Shift Strategy for Near-Infrared Fluorescence Switchable Dye and the Imaging Applications HJ Chen, CY Chew, EH Chang, YW Tu, LY Wei, BH Wu, CH Chen, ... Journal of the American Chemical Society 140 (15), 5224-5234, 2018 | 62 | 2018 |
Development of a highly α-regioselective indium-mediated allylation reaction in water TP Loh, KT Tan, JY Yang, CL Xiang Tetrahedron Letters 42 (49), 8701-8703, 2001 | 61 | 2001 |
A rapid SNAP-tag fluorogenic probe based on an environment-sensitive fluorophore for no-wash live cell imaging TK Liu, PY Hsieh, YD Zhuang, CY Hsia, CL Huang, HP Lai, HS Lin, ... ACS Chemical Biology 9 (10), 2359-2365, 2014 | 59 | 2014 |
The first example of enantioselective allyl transfer from a linear homoallylic alcohol to an aldehyde TP Loh, CL Ken Lee, KT Tan Organic Letters 4 (17), 2985-2987, 2002 | 58 | 2002 |