Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology L Piccoli, YJ Park, MA Tortorici, N Czudnochowski, AC Walls, ... Cell 183 (4), 1024-1042. e21, 2020 | 1366 | 2020 |
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β CE Zielinski, F Mele, D Aschenbrenner, D Jarrossay, F Ronchi, ... Nature 484 (7395), 514-518, 2012 | 1105 | 2012 |
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection K Stettler, M Beltramello, DA Espinosa, V Graham, A Cassotta, S Bianchi, ... Science 353 (6301), 823-826, 2016 | 862 | 2016 |
Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations S Okada, JG Markle, EK Deenick, F Mele, D Averbuch, M Lagos, ... Science 349 (6248), 606-613, 2015 | 429 | 2015 |
Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines S Becattini, D Latorre, F Mele, M Foglierini, C De Gregorio, A Cassotta, ... Science 347 (6220), 400-406, 2015 | 373 | 2015 |
T cells in patients with narcolepsy target self-antigens of hypocretin neurons D Latorre, U Kallweit, E Armentani, M Foglierini, F Mele, A Cassotta, ... Nature 562 (7725), 63-68, 2018 | 295 | 2018 |
Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 … CS Lindestam Arlehamn, A Gerasimova, F Mele, R Henderson, J Swann, ... PLoS pathogens 9 (1), e1003130, 2013 | 252 | 2013 |
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23 R Martínez-Barricarte, JG Markle, CS Ma, EK Deenick, N Ramírez-Alejo, ... Science immunology 3 (30), eaau6759, 2018 | 179 | 2018 |
Dissecting the human immunologic memory for pathogens CE Zielinski, D Corti, F Mele, D Pinto, A Lanzavecchia, F Sallusto Immunological reviews 240 (1), 40-51, 2011 | 144 | 2011 |
Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2 JS Low, D Vaqueirinho, F Mele, M Foglierini, J Jerak, M Perotti, ... Science 372 (6548), 1336-1341, 2021 | 134 | 2021 |
Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria R Yang, F Mele, L Worley, D Langlais, J Rosain, I Benhsaien, H Elarabi, ... Cell 183 (7), 1826-1847. e31, 2020 | 113 | 2020 |
ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies JS Low, J Jerak, MA Tortorici, M McCallum, D Pinto, A Cassotta, ... Science 377 (6607), 735-742, 2022 | 106 | 2022 |
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency XF Kong, R Martinez-Barricarte, J Kennedy, F Mele, T Lazarov, ... Nature immunology 19 (9), 973-985, 2018 | 103 | 2018 |
Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland L Piccoli, P Ferrari, G Piumatti, S Jovic, BF Rodriguez, F Mele, ... The Lancet Regional Health–Europe 1, 2021 | 91 | 2021 |
Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes CS Lindestam Arlehamn, S Paul, F Mele, C Huang, JA Greenbaum, R Vita, ... Proceedings of the National Academy of Sciences 112 (2), E147-E155, 2015 | 67 | 2015 |
Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria Q Philippot, M Ogishi, J Bohlen, J Puchan, AA Arias, T Nguyen, ... Science immunology 8 (80), eabq5204, 2023 | 40 | 2023 |
ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells F Mele, C Basso, C Leoni, D Aschenbrenner, S Becattini, D Latorre, ... Nature communications 6 (1), 6431, 2015 | 37 | 2015 |
Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with … F Mele, C Fornara, D Jarrossay, M Furione, A Arossa, A Spinillo, ... PLoS One 12 (11), e0187731, 2017 | 27 | 2017 |
High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency R Yang, M Weisshaar, F Mele, I Benhsaien, K Dorgham, J Han, CA Croft, ... Journal of Experimental Medicine 218 (8), e20202726, 2021 | 26 | 2021 |
Longitudinal postvaccine SARS-CoV-2 immunoglobulin G titers, memory B-cell responses, and risk of COVID-19 in multiple sclerosis over 1 year G Disanto, A Galante, M Cantu', R Sacco, F Mele, JJ Eisler, F Keller, ... Neurology: Neuroimmunology & Neuroinflammation 10 (1), e200043, 2022 | 19 | 2022 |