A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia N Baryawno, D Przybylski, MS Kowalczyk, Y Kfoury, N Severe, ... Cell 177 (7), 1915-1932. e16, 2019 | 717 | 2019 |
Xist RNA is a potent suppressor of hematologic cancer in mice E Yildirim, JE Kirby, DE Brown, FE Mercier, RI Sadreyev, DT Scadden, ... Cell 152 (4), 727-742, 2013 | 540 | 2013 |
Inhibition of dihydroorotate dehydrogenase overcomes differentiation blockade in acute myeloid leukemia DB Sykes, YS Kfoury, FE Mercier, MJ Wawer, JM Law, MK Haynes, ... Cell 167 (1), 171-186. e15, 2016 | 457 | 2016 |
The bone marrow at the crossroads of blood and immunity FE Mercier, C Ragu, DT Scadden Nature Reviews Immunology 12 (1), 49-60, 2012 | 380 | 2012 |
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias SM Sykes, SW Lane, L Bullinger, D Kalaitzidis, R Yusuf, B Saez, F Ferraro, ... Cell 146 (5), 697-708, 2011 | 301 | 2011 |
Engineering pulmonary vasculature in decellularized rat and human lungs X Ren, PT Moser, SE Gilpin, T Okamoto, T Wu, LF Tapias, FE Mercier, ... Nature biotechnology 33 (10), 1097-1102, 2015 | 250 | 2015 |
Proximity-based differential single-cell analysis of the niche to identify stem/progenitor cell regulators L Silberstein, KA Goncalves, PV Kharchenko, R Turcotte, Y Kfoury, ... Cell stem cell 19 (4), 530-543, 2016 | 162 | 2016 |
Rapid mobilization reveals a highly engraftable hematopoietic stem cell J Hoggatt, P Singh, TA Tate, BK Chou, SR Datari, S Fukuda, L Liu, ... Cell 172 (1), 191-204. e10, 2018 | 118 | 2018 |
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers RZ Yusuf, B Saez, A Sharda, N Van Gastel, VWC Yu, N Baryawno, ... Blood, The Journal of the American Society of Hematology 136 (11), 1303-1316, 2020 | 85 | 2020 |
Single targeted exon mutation creates a true congenic mouse for competitive hematopoietic stem cell transplantation: The C57BL/6-CD45. 1STEM mouse FE Mercier, DB Sykes, DT Scadden Stem cell reports 6 (6), 985-992, 2016 | 75 | 2016 |
In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors D Duguay, F Mercier, J Stagg, D Martineau, J Bramson, M Servant, R Lin, ... Cancer research 62 (18), 5148-5152, 2002 | 66 | 2002 |
Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Rα on central and effector memory CD4+ and CD8+ T cell subsets F Mercier, MR Boulassel, B Yassine-Diab, C Tremblay, NF Bernard, ... Clinical & Experimental Immunology 152 (1), 72-80, 2008 | 54 | 2008 |
Immunophenotypic patterns of CD8+ T cell subsets expressing CD8αα and IL-7Rα in viremic, aviremic and slow progressor HIV-1-infected subjects MR Boulassel, F Mercier, N Gilmore, JP Routy Clinical Immunology 124 (2), 149-157, 2007 | 41 | 2007 |
Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth CH Man, FE Mercier, N Liu, W Dong, G Stephanopoulos, L Jiang, Y Jung, ... Blood, The Journal of the American Society of Hematology 139 (4), 502-522, 2022 | 33 | 2022 |
Progression signature underlies clonal evolution and dissemination of multiple myeloma YJ Shen, Y Mishima, J Shi, R Sklavenitis-Pistofidis, RA Redd, ... Blood, The Journal of the American Society of Hematology 137 (17), 2360-2372, 2021 | 33 | 2021 |
Amino acid–insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells D Kalaitzidis, D Lee, A Efeyan, Y Kfoury, N Nayyar, DB Sykes, FE Mercier, ... The Journal of clinical investigation 127 (4), 1405-1413, 2017 | 31 | 2017 |
Not all created equal: lineage hard-wiring in the production of blood FE Mercier, DT Scadden Cell 163 (7), 1568-1570, 2015 | 29 | 2015 |
SnapShot: The Hematopoietic Stem Cell Niche Y Kfoury, F Mercier, DT Scadden Cell 158 (1), 228-228. e1, 2014 | 26 | 2014 |
Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML T Oki, F Mercier, H Kato, Y Jung, TO McDonald, JA Spencer, MC Mazzola, ... Nature communications 12 (1), 245, 2021 | 24 | 2021 |
tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche YS Kfoury, F Ji, M Mazzola, DB Sykes, AK Scherer, A Anselmo, Y Akiyama, ... Cell Stem Cell 28 (12), 2090-2103. e9, 2021 | 23 | 2021 |