| Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human subjects and animal … L Egaña-Gorroño, R López-Díez, G Yepuri, LS Ramirez, S Reverdatto, ... Frontiers in cardiovascular medicine 7, 37, 2020 | 182 | 2020 |
| Hyperactive S6K1 mediates oxidative stress and endothelial dysfunction in aging: inhibition by resveratrol AG Rajapakse, G Yepuri, JM Carvas, S Stein, CM Matter, I Scerri, ... PloS one 6 (4), e19237, 2011 | 166 | 2011 |
| Proton pump inhibitors accelerate endothelial senescence G Yepuri, R Sukhovershin, TZ Nazari-Shafti, M Petrascheck, YT Ghebre, ... Circulation research 118 (12), e36-e42, 2016 | 153 | 2016 |
| Arginase II promotes macrophage inflammatory responses through mitochondrial reactive oxygen species, contributing to insulin resistance and atherogenesis XF Ming, AG Rajapakse, G Yepuri, Y Xiong, JM Carvas, J Ruffieux, ... Journal of the American Heart Association 1 (4), e000992, 2012 | 153 | 2012 |
| ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis Y Xiong, G Yepuri, M Forbiteh, Y Yu, JP Montani, Z Yang, XF Ming Autophagy 10 (12), 2223-2238, 2014 | 122 | 2014 |
| Positive crosstalk between arginase‐II and S6K1 in vascular endothelial inflammation and aging G Yepuri, S Velagapudi, Y Xiong, AG Rajapakse, JP Montani, XF Ming, ... Aging cell 11 (6), 1005-1016, 2012 | 118 | 2012 |
| Aldose reductase: an emerging target for development of interventions for diabetic cardiovascular complications S Jannapureddy, M Sharma, G Yepuri, AM Schmidt, R Ramasamy Frontiers in endocrinology 12, 636267, 2021 | 79 | 2021 |
| Endothelium-derived nitric oxide as an antiatherogenic mechanism: implications for therapy RA Sukhovershin, G Yepuri, YT Ghebremariam Methodist DeBakey cardiovascular journal 11 (3), 166, 2015 | 64 | 2015 |
| Period2 gene mutant mice show compromised insulin-mediated endothelial nitric oxide release and altered glucose homeostasis JM Carvas, A Vukolic, G Yepuri, Y Xiong, K Popp, I Schmutz, S Chappuis, ... Frontiers in physiology 3, 337, 2012 | 58 | 2012 |
| Arginase-II deficiency extends lifespan in mice Y Xiong, G Yepuri, JP Montani, XF Ming, Z Yang Frontiers in physiology 8, 682, 2017 | 38 | 2017 |
| Arginase-II promotes tumor necrosis factor-α release from pancreatic acinar cells causing β-cell apoptosis in aging Y Xiong, G Yepuri, S Necetin, JP Montani, XF Ming, Z Yang Diabetes 66 (6), 1636-1649, 2017 | 36 | 2017 |
| Significance and mechanistic relevance of SIRT6-mediated endothelial dysfunction in cardiovascular disease progression G Yepuri, R Ramasamy Circulation research 124 (10), 1408-1410, 2019 | 22 | 2019 |
| DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress G Yepuri, LM Ramirez, GG Theophall, SV Reverdatto, N Quadri, ... Nature Communications 14 (1), 6900, 2023 | 10 | 2023 |
| DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice L Senatus, L Egaña-Gorroño, R López-Díez, S Bergaya, JF Aranda, ... Communications biology 6 (1), 280, 2023 | 9 | 2023 |
| Aldose reductase promotes diet‐induced obesity via induction of senescence in subcutaneous adipose tissue D Thiagarajan, N Quadri, S Jawahar, H Zirpoli, CH Del Pozo, ... Obesity 30 (8), 1647-1658, 2022 | 9 | 2022 |
| 1080-P: addressing the safety challenges of aldose reductase inhibition: development of AT-001 for diabetic cardiomyopathy, a potent and selective next generation aldose … R Perfetti, G Yepuri, NA Quadri, AF Ghannam, R Ramasamy, ... Diabetes 69 (Supplement_1), 2020 | 5 | 2020 |
| Heme & RAGE: A new opportunistic relationship? G Yepuri, A Shekhtman, A Marie Schmidt, R Ramasamy The FEBS Journal 288 (11), 3424-3427, 2021 | 4 | 2021 |
| Macrophage-adipocyte communication and cardiac remodeling G Yepuri, SN Hasan, AM Schmidt, R Ramasamy The Journal of Experimental Medicine 218 (9), 2021 | 3 | 2021 |
| The cardioprotective role of sirtuins is mediated in part by regulating KATP channel surface expression E Tuncay, I Gando, JY Huo, G Yepuri, N Samper, B Turan, HQ Yang, ... American Journal of Physiology-Cell Physiology 324 (5), C1017-C1027, 2023 | 2 | 2023 |
| Endothelial dysfunction, a major event in atherosclerosis: PPIs impair endothelial function through activation of PAI-1 G Yepuri, R Sukhovershin, TZ Nazari-shafti, YT Ghebremariam, JP Cooke Atherosclerosis 241 (1), e5, 2015 | 2 | 2015 |
