Characterization of a two-component system, devR-devS, of Mycobacterium tuberculosis N Dasgupta, V Kapur, KK Singh, TK Das, S Sachdeva, K Jyothisri, ... Tubercle and Lung Disease 80 (3), 141-159, 2000 | 267 | 2000 |
DevR–DevS is a bona fide two-component system of Mycobacterium tuberculosis that is hypoxia-responsive in the absence of the DNA-binding domain of DevR DK Saini, V Malhotra, D Dey, N Pant, TK Das, JS Tyagi Microbiology 150 (4), 865-875, 2004 | 203 | 2004 |
Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis V Malhotra, D Sharma, VD Ramanathan, H Shakila, DK Saini, ... FEMS Microbiology Letters 231 (2), 237-245, 2004 | 167 | 2004 |
Cross talk between DevS sensor kinase homologue, Rv2027c, and DevR response regulator of Mycobacterium tuberculosis DK Saini, V Malhotra, JS Tyagi FEBS letters 565 (1-3), 75-80, 2004 | 115 | 2004 |
The prrAB Two-Component System Is Essential for Mycobacterium tuberculosis Viability and Is Induced under Nitrogen-Limiting Conditions SE Haydel, V Malhotra, GL Cornelison, JE Clark-Curtiss Journal of bacteriology 194 (2), 354-361, 2012 | 78 | 2012 |
Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent … V Malhotra, LT Arteaga-Cortes, G Clay, JE Clark-Curtiss Microbiology 156 (9), 2829-2841, 2010 | 60 | 2010 |
The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition SB Korch, V Malhotra, H Contreras, JE Clark-Curtiss Journal of Microbiology 53, 783-795, 2015 | 52 | 2015 |
Mycobacterium tuberculosis response regulators, DevR and NarL, interact in vivo and co-regulate gene expression during aerobic nitrate metabolism V Malhotra, R Agrawal, TR Duncan, DK Saini, JE Clark-Curtiss Journal of Biological Chemistry 290 (13), 8294-8309, 2015 | 41 | 2015 |
Mycobacterium tuberculosis protein kinase K enables growth adaptation through translation control V Malhotra, BP Okon, JE Clark-Curtiss Journal of bacteriology 194 (16), 4184-4196, 2012 | 30 | 2012 |
DevR-mediated adaptive response in Mycobacterium tuberculosis H37Ra: links to asparagine metabolism V Malhotra, JS Tyagi, JE Clark-Curtiss Tuberculosis 89 (2), 169-174, 2009 | 29 | 2009 |
Interplay of PhoP and DevR response regulators defines expression of the dormancy regulon in virulent Mycobacterium tuberculosis A Vashist, V Malhotra, G Sharma, JS Tyagi, JE Clark-Curtiss Journal of Biological Chemistry 293 (42), 16413-16425, 2018 | 22 | 2018 |
Acetylation of Response Regulator Proteins, TcrX and MtrA in M. tuberculosis Tunes their Phosphotransfer Ability and Modulates Two-Component Signaling Crosstalk KK Singh, N Bhardwaj, GD Sankhe, N Udaykumar, R Singh, V Malhotra, ... Journal of molecular biology, 2019 | 19 | 2019 |
Mycobacterium tuberculosis PknK substrate profiling reveals essential transcription terminator protein Rho and two-component response regulators PrrA and MtrA as novel targets … V Malhotra, BP Okon, AT Satsangi, S Das, UW Waturuocha, A Vashist, ... Microbiology Spectrum 10 (2), e01354-21, 2022 | 15 | 2022 |
Cyclic di‐GMP sensing histidine kinase PdtaS controls mycobacterial adaptation to carbon sources VN Hariharan, R Yadav, C Thakur, A Singh, R Gopinathan, DP Singh, ... The FASEB Journal 35 (4), e21475, 2021 | 14 | 2021 |
A Low-Prevalence Single-Nucleotide Polymorphism in the Sensor Kinase PhoR in Mycobacterium tuberculosis Suppresses Its Autophosphatase Activity and … UW Waturuocha, MS Krishna, V Malhotra, NM Dixit, DK Saini Frontiers in microbiology 12, 724482, 2021 | 8 | 2021 |
In silico evidence for extensive Ser/Thr phosphorylation of Mycobacterium tuberculosis two-component signalling systems. A Garg, N Khurana, A Chugh, K Verma, V Malhotra Current Science (00113891) 123 (9), 2022 | 2 | 2022 |
A high-frequency single nucleotide polymorphism in the MtrB sensor kinase in clinical strains of Mycobacterium tuberculosis alters its biochemical and physiological properties DK Waturuocha, U. W., P. J., A., Singh, K. K., Malhotra, V., Krishna, M. S ... PLoS ONE, e0256664, 2021 | 2 | 2021 |
Selective promotion of oligonucleotides in the course of evolution B Mathew, A Halder, S Panda, N Jaiswal, D Pramanik, SCM Peela, ... bioRxiv, 2024.07. 05.602168, 2024 | | 2024 |
Anti-cancer drug Tamoxifen interferes with Mycobacterium tuberculosis PhoPR mediated signaling and inhibits mycobacterial growth A Garg, M Pandit, V Malhotra, DK Saini bioRxiv, 2023.12. 19.571805, 2023 | | 2023 |
Ser/Thr Phosphorylation of Mycobacterium tuberculosis Type II Rel TA module by Protein Kinase K interferes with toxin neutralization: A novel mode of TA regulation. SR Sarah, A Garg, S Korch, A Gupta, V Malhotra bioRxiv, 2023.12. 15.571532, 2023 | | 2023 |