| The prevalence of PIK3CA mutations in gastric and colon cancer S Velho, C Oliveira, A Ferreira, AC Ferreira, G Suriano, S Schwartz Jr, ... European journal of cancer 41 (11), 1649-1654, 2005 | 486 | 2005 |
| A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function SA Melo, S Ropero, C Moutinho, LA Aaltonen, H Yamamoto, GA Calin, ... Nature genetics 41 (3), 365-370, 2009 | 466 | 2009 |
| A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells SA Melo, C Moutinho, S Ropero, GA Calin, S Rossi, R Spizzo, ... Cancer cell 18 (4), 303-315, 2010 | 445 | 2010 |
| β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer SP Tenbaum, P Ordóñez-Morán, I Puig, I Chicote, O Arqués, S Landolfi, ... Nature medicine 18 (6), 892-901, 2012 | 432 | 2012 |
| A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition S Ropero, MF Fraga, E Ballestar, R Hamelin, H Yamamoto, ... Nature genetics 38 (5), 566-569, 2006 | 351 | 2006 |
| Frameshift Mutations at Mononucleotide Repeats in caspase-5 and Other Target Genes in Endometrial and Gastrointestinal Cancer of the Microsatellite Mutator … S Schwartz Jr, H Yamamoto, M Navarro, M Maestro, J Reventós, ... Cancer research 59 (12), 2995-3002, 1999 | 318 | 1999 |
| KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression C Oliveira, S Velho, C Moutinho, A Ferreira, A Preto, E Domingo, ... Oncogene 26 (1), 158-163, 2007 | 290 | 2007 |
| SMAD4 as a prognostic marker in colorectal cancer H Alazzouzi, P Alhopuro, R Salovaara, H Sammalkorpi, H Järvinen, ... Clinical Cancer Research 11 (7), 2606-2611, 2005 | 248 | 2005 |
| Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status C Oliveira, JL Westra, D Arango, M Ollikainen, E Domingo, A Ferreira, ... Human molecular genetics 13 (19), 2303-2311, 2004 | 239 | 2004 |
| BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes E Domingo, RC Niessen, C Oliveira, P Alhopuro, C Moutinho, E Espín, ... Oncogene 24 (24), 3995-3998, 2005 | 220 | 2005 |
| Somatic Mutations in the DNA Damage-Response Genes ATR and CHK1 in Sporadic Stomach Tumors with Microsatellite Instability A Menoyo, H Alazzouzi, E Espin, M Armengol, H Yamamoto, ... Cancer research 61 (21), 7727-7730, 2001 | 203 | 2001 |
| Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis P Laiho, A Kokko, S Vanharanta, R Salovaara, H Sammalkorpi, ... Oncogene 26 (2), 312-320, 2007 | 191 | 2007 |
| BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency C Oliveira, M Pinto, A Duval, C Brennetot, E Domingo, E Espín, ... Oncogene 22 (57), 9192-9196, 2003 | 179 | 2003 |
| Gene-expression profiling predicts recurrence in Dukes’ C colorectal cancer D Arango, P Laiho, A Kokko, P Alhopuro, H Sammalkorpi, R Salovaara, ... Gastroenterology 129 (3), 874-884, 2005 | 158 | 2005 |
| Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics JL Corchero, B Gasser, D Resina, W Smith, E Parrilli, F Vázquez, ... Biotechnology advances 31 (2), 140-153, 2013 | 149 | 2013 |
| TNFα-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion R Kandhaya-Pillai, F Miro-Mur, J Alijotas-Reig, T Tchkonia, JL Kirkland, ... Aging (albany NY) 9 (11), 2411, 2017 | 134 | 2017 |
| Na+/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: Molecular characterization of SMCT V Paroder, SR Spencer, M Paroder, D Arango, S Schwartz Jr, ... Proceedings of the National Academy of Sciences 103 (19), 7270-7275, 2006 | 134 | 2006 |
| SMAD4 levels and response to 5-fluorouracil in colorectal cancer P Alhopuro, H Alazzouzi, H Sammalkorpi, V Dávalos, R Salovaara, ... Clinical cancer research 11 (17), 6311-6316, 2005 | 132 | 2005 |
| Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation P Botella, I Abasolo, Y Fernández, C Muniesa, S Miranda, M Quesada, ... Journal of controlled release 156 (2), 246-257, 2011 | 126 | 2011 |
| Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors H Alazzouzi, V Davalos, A Kokko, E Domingo, SM Woerner, AJ Wilson, ... Cancer research 65 (22), 10170-10173, 2005 | 125 | 2005 |