| Tetrahydroindazolone substituted 2-aminobenzamides as fluorescent probes: switching metal ion selectivity from zinc to cadmium by interchanging the amino and carbamoyl groups … J Jia, QC Xu, R Li, X Tang, YF He, MY Zhang, Y Zhang, GW Xing Organic & Biomolecular Chemistry 10 (31), 6279-6286, 2012 | 36 | 2012 |
| 1-(4-[18F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ1 Receptors in the Brain Y He, F Xie, J Ye, W Deuther-Conrad, B Cui, L Wang, J Lu, J Steinbach, ... Journal of medicinal chemistry 60 (10), 4161-4172, 2017 | 28 | 2017 |
| 18F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain L Wang, J Ye, Y He, W Deuther-Conrad, J Zhang, X Zhang, M Cui, ... Bioorganic & medicinal chemistry 25 (14), 3792-3802, 2017 | 20 | 2017 |
| Development of high brain-penetrant and reversible monoacylglycerol lipase PET tracers for neuroimaging Y He, M Schild, U Grether, J Benz, L Leibrock, D Heer, A Topp, L Collin, ... Journal of medicinal chemistry 65 (3), 2191-2207, 2022 | 11 | 2022 |
| Positron Emission Tomography Imaging Evaluation of a Novel 18F-Labeled Sigma-1 Receptor Radioligand in Cynomolgus Monkeys H Jia, Z Cai, D Holden, Y He, S Lin, S Li, E Baum, A Shirali, M Kapinos, ... ACS Chemical Neuroscience 11 (11), 1673-1681, 2020 | 11 | 2020 |
| Recent progress in allosteric modulators for GluN2A subunit and development of GluN2A‐selective nuclear imaging probes Y He, L Mu, SM Ametamey, R Schibli Journal of Labelled Compounds and Radiopharmaceuticals 62 (8), 552-560, 2019 | 8 | 2019 |
| Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold Y He, LC Gobbi, AM Herde, D Rombach, M Ritter, B Kuhn, MB Wittwer, ... Nuclear Medicine and Biology 108, 24-32, 2022 | 7 | 2022 |
| Synthesis and evaluation of new 1-oxa-8-azaspiro [4.5] decane derivatives as candidate radioligands for sigma-1 receptors J Tian, Y He, W Deuther-Conrad, H Fu, F Xie, Y Zhang, T Wang, X Zhang, ... Bioorganic & Medicinal Chemistry 28 (14), 115560, 2020 | 7 | 2020 |
| Ketamine and ceftriaxone-induced alterations in glutamate levels do not impact the specific binding of metabotropic glutamate receptor subtype 5 radioligand [18F] PSS232 in the … A Müller Herde, SD Boss, Y He, R Schibli, L Mu, SM Ametamey Pharmaceuticals 11 (3), 83, 2018 | 7 | 2018 |
| Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain Y He, U Grether, MF Taddio, C Meier, C Keller, MR Edelmann, M Honer, ... European Journal of Medicinal Chemistry 243, 114750, 2022 | 5 | 2022 |
| Radiolabeled compounds L Collin, M Edelmann, L Gobbi, U Grether, T Hartung, HE Yingfang, ... US Patent App. 17/692,632, 2022 | 5 | 2022 |
| Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer’s disease: A [18F]PSS232 PET/MRI study J Wang, Y He, X Chen, L Huang, J Li, Z You, Q Huang, S Ren, K He, ... Alzheimer's Research & Therapy 16 (1), 9, 2024 | 4 | 2024 |
| Proof-of-concept optimization of a copper-mediated 18 F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation Y Lu, Y He, R Schibli, L Mu, RM van Dam Lab on a Chip 23 (21), 4652-4663, 2023 | 2 | 2023 |
| Evaluation of 5H‐Thiazolo[3,2‐α]pyrimidin‐5‐ones as Potential GluN2A PET Tracers Y He, DM Whitehead, E Briard, S Numao, L Mu, R Schibli, SM Ametamey, ... ChemMedChem 15 (24), 2448-2461, 2020 | 2 | 2020 |
| Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2 J Wang, D Beyer, C Vaccarin, Y He, M Tanriver, R Benoit, X Deupi, L Mu, ... European Journal of Nuclear Medicine and Molecular Imaging, 1-13, 2024 | 1 | 2024 |
| Identification of (R)-[18F] YH134 for monoacylglycerol lipase neuroimaging and exploration of its use for central nervous system and peripheral drug development Y He, SD Krämer, U Grether, MB Wittwer, L Collin, B Kuhn, A Topp, ... Journal of Nuclear Medicine 65 (2), 300-305, 2024 | 1 | 2024 |
| Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche’s … J Aebi, K Atz, SM Ametamey, J Benz, J Blaising, S Butini, G Campiani, ... Chimia 78 (7-8), 499-512, 2024 | | 2024 |
| Magl inhibitors LC Gobbi, UM Grether, HE Yingfang, B Kuhn, L Mu US Patent App. 18/593,350, 2024 | | 2024 |
| Evaluation of 11C-YH168 as a novel radiotracer for monoacylglycerol lipase and comparison with 18F-T401 in non-human primates MQ Zheng, J GU, D Holden, Y He, H Gao, H Zhang, M Crosby, J Ropchan, ... Journal of Nuclear Medicine 65 (supplement 2), 242296-242296, 2024 | | 2024 |
| Preclinical Evaluation of the Reversible Monoacylglycerol Lipase PET Tracer (R)‐[11C]YH132: Application in Drug Development and Neurodegenerative Diseases Y He, A Delparente, CVML Jie, C Keller, R Humm, D Heer, L Collin, ... ChemBioChem 25 (7), e202300819, 2024 | | 2024 |