Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis JD Rioux, RJ Xavier, KD Taylor, MS Silverberg, P Goyette, A Huett, ... Nature genetics 39 (5), 596-604, 2007 | 2170 | 2007 |
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease SA McCarroll, A Huett, P Kuballa, SD Chilewski, A Landry, P Goyette, ... Nature genetics 40 (9), 1107-1112, 2008 | 857 | 2008 |
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant P Kuballa, A Huett, JD Rioux, MJ Daly, RJ Xavier PloS one 3 (10), e3391, 2008 | 438 | 2008 |
Crohn's disease‐associated adherent‐invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly P Lapaquette, AL Glasser, A Huett, RJ Xavier, A Darfeuille‐Michaud Cellular microbiology 12 (1), 99-113, 2010 | 396 | 2010 |
Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium S Wiles, S Clare, J Harker, A Huett, D Young, G Dougan, G Frankel Cellular microbiology 6 (10), 963-972, 2004 | 283 | 2004 |
The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium A Huett, RJ Heath, J Begun, SO Sassi, LA Baxt, JM Vyas, MB Goldberg, ... Cell host & microbe 12 (6), 778-790, 2012 | 238 | 2012 |
Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity ACY Ng, JM Eisenberg, RJW Heath, A Huett, CM Robinson, GJ Nau, ... Proceedings of the National Academy of Sciences 108 (supplement_1), 4631-4638, 2011 | 223 | 2011 |
Crohn disease: a current perspective on genetics, autophagy and immunity TS Stappenbeck, JD Rioux, A Mizoguchi, T Saitoh, A Huett, ... Autophagy 7 (4), 355-374, 2011 | 138 | 2011 |
Autophagy as an important process in gut homeostasis and Crohn’s disease pathogenesis RJ Xavier, A Huett, JD Rioux Gut 57 (6), 717-720, 2008 | 92 | 2008 |
Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice CKF Li, SLF Pender, KM Pickard, V Chance, JA Holloway, A Huett, ... The Journal of Immunology 173 (8), 5171-5179, 2004 | 85 | 2004 |
Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria … F Bowe, EC Lavelle, EA McNeela, C Hale, S Clare, B Arico, MM Giuliani, ... Infection and immunity 72 (7), 4052-4060, 2004 | 78 | 2004 |
A systems biology viewpoint on autophagy in health and disease A Huett, G Goel, RJ Xavier Current opinion in gastroenterology 26 (4), 302-309, 2010 | 64 | 2010 |
A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy A Huett, A Ng, Z Cao, P Kuballa, M Komatsu, MJ Daly, DK Podolsky, ... The Journal of Immunology 182 (8), 4917-4930, 2009 | 58 | 2009 |
Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling SC Wei, IM Rosenberg, Z Cao, AS Huett, RJ Xavier, DK Podolsky Inflammatory bowel diseases 18 (5), 877-888, 2012 | 55 | 2012 |
DLGH1 is a negative regulator of T-lymphocyte proliferation LM Stephenson, B Sammut, DB Graham, J Chan-Wang, KL Brim, ... Molecular and cellular biology 27 (21), 7574-7581, 2007 | 49 | 2007 |
DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell–cell contact Z Cao, A Huett, P Kuballa, C Giallourakis, RJ Xavier Cellular signalling 20 (1), 73-82, 2008 | 37 | 2008 |
Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases A Huett, RJ Xavier Inflammatory bowel diseases 16 (1), 152-174, 2010 | 36 | 2010 |
Vaccines against human enteric bacterial pathogens G Dougan, A Huett, S Clare British medical bulletin 62 (1), 113-123, 2002 | 34 | 2002 |
Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells F Pérez-Cota, R Fuentes-Domínguez, S La Cavera, W Hardiman, M Yao, ... Journal of Applied Physics 128 (16), 2020 | 33 | 2020 |
The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements A Huett, JM Leong, DK Podolsky, RJ Xavier Experimental cell research 315 (12), 2001-2011, 2009 | 21 | 2009 |