| Opposing effects on NaV1. 2 function underlie differences between SCN2A variants observed in individuals with autism spectrum disorder or infantile seizures R Ben-Shalom, CM Keeshen, KN Berrios, JY An, SJ Sanders, KJ Bender Biological psychiatry 82 (3), 224-232, 2017 | 259 | 2017 |
| The autism-associated gene Scn2a contributes to dendritic excitability and synaptic function in the prefrontal cortex PWE Spratt, R Ben-Shalom, CM Keeshen, KJ Burke, RL Clarkson, ... Neuron 103 (4), 673-685. e5, 2019 | 179 | 2019 |
| Paradoxical hyperexcitability from NaV1. 2 sodium channel loss in neocortical pyramidal cells PWE Spratt, RPD Alexander, R Ben-Shalom, A Sahagun, H Kyoung, ... Cell Reports 36 (5), 2021 | 67 | 2021 |
| Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons JC Athilingam, R Ben-Shalom, CM Keeshen, VS Sohal, KJ Bender Elife 6, e31991, 2017 | 51 | 2017 |
| Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants CH Thompson, R Ben-Shalom, KJ Bender, AL George Journal of General Physiology 152 (3), 2020 | 37 | 2020 |
| β-arrestin-dependent dopaminergic regulation of calcium channel activity in the axon initial segment S Yang, R Ben-Shalom, M Ahn, AT Liptak, RM van Rijn, JL Whistler, ... Cell reports 16 (6), 1518-1526, 2016 | 37 | 2016 |
| Optimizing ion channel models using a parallel genetic algorithm on graphical processors R Ben-Shalom, A Aviv, B Razon, A Korngreen Journal of Neuroscience Methods 206 (2), 183-194, 2012 | 31 | 2012 |
| Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice DM Echevarria-Cooper, NA Hawkins, SN Misra, AM Huffman, T Thaxton, ... Human molecular genetics 31 (17), 2964-2988, 2022 | 22 | 2022 |
| Accelerating compartmental modeling on a graphical processing unit R Ben-Shalom, G Liberman, A Korngreen Frontiers in neuroinformatics 7, 4, 2013 | 22 | 2013 |
| NeuroGPU: Accelerating multi-compartment, biophysically detailed neuron simulations on GPUs R Ben-Shalom, A Ladd, NS Artherya, C Cross, KG Kim, H Sanghevi, ... Journal of neuroscience methods 366, 109400, 2022 | 17* | 2022 |
| CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder S Tamura, AD Nelson, PWE Spratt, H Kyoung, X Zhou, Z Li, J Zhao, ... BioRxiv, 2022.03. 30.486483, 2022 | 16 | 2022 |
| Inferring neuronal ionic conductances from membrane potentials using cnns R Ben-Shalom, J Balewski, A Siththaranjan, V Baratham, H Kyoung, ... bioRxiv, 727974, 2019 | 9 | 2019 |
| Scaling and Benchmarking an Evolutionary Algorithm for constructing biophysical neuronal models A Ladd, KG Kim, J Balewski, K Bouchard, R Ben-Shalom Frontiers in Neuroinformatics 16, 882552, 2022 | 3 | 2022 |
| The autism-associated gene Scn2a plays an essential role in synaptic stability and learning PWE Spratt, R Ben-Shalom, CM Keeshen, KJ Burke Jr, RL Clarkson, ... bioRxiv, 366781, 2018 | 2 | 2018 |
| Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy S Quinn, N Zhang, TA Fenton, M Brusel, P Muruganandam, Y Peleg, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1870 (5), 167127, 2024 | 1 | 2024 |
| Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations TA Fenton, OY Haouchine, EL Hallam, EM Smith, KC Jackson, ... bioRxiv, 2023.07. 24.550093, 2023 | 1 | 2023 |
| Structural, biophysical, and neurophysiological effects of SCN2A mutations SMA Wafa, G Yazdani, TA Fenton, CH Thompson, R Ben-Shalom, ... Biophysical Journal 123 (3), 12a, 2024 | | 2024 |
| The SCN8A p.(Gly1625Arg) variant associated with developmental and epileptic encephalopathy causes complex biophysical changes and reduced neuronal firing S Quinn, N Zhang, TA Fenton, M Brusel, P Muruganandam, Y Peleg, ... bioRxiv, 2023 | | 2023 |
| Biophysical Mechanism of the Action Potential Initiation and Propagation in Cortical Pyramidal Neurons R Ben-Shalom Bar-Ilan University, 2014 | | 2014 |
| Using stochastic algorithms for constraining compartmental and markov channel models R Ben-Shalom, A Korngreen BMC Neuroscience 10 (Suppl 1), P35, 2009 | | 2009 |
