| Molecular properties that influence the oral bioavailability of drug candidates DF Veber, SR Johnson, HY Cheng, BR Smith, KW Ward, KD Kopple Journal of medicinal chemistry 45 (12), 2615-2623, 2002 | 7819 | 2002 |
| Ligand and target discovery by fragment-based screening in human cells CG Parker, A Galmozzi, Y Wang, BE Correia, K Sasaki, CM Joslyn, ... Cell 168 (3), 527-541. e29, 2017 | 389 | 2017 |
| In silico ADME/Tox: why models fail TR Stouch, JR Kenyon, SR Johnson, XQ Chen, A Doweyko, Y Li Journal of computer-aided molecular design 17, 83-92, 2003 | 229 | 2003 |
| The trouble with QSAR (or how I learned to stop worrying and embrace fallacy) SR Johnson Journal of chemical information and modeling 48 (1), 25-26, 2008 | 220 | 2008 |
| Identification of multiple analytes using an optical sensor array and pattern recognition neural networks SR Johnson, JM Sutter, HL Engelhardt, PC Jurs, J White, JS Kauer, ... Analytical Chemistry 69 (22), 4641-4648, 1997 | 118 | 1997 |
| Recent progress in the computational prediction of aqueous solubility and absorption SR Johnson, W Zheng The AAPS journal 8, E27-E40, 2006 | 116 | 2006 |
| Tyrosine kinase 2-mediated signal transduction in T lymphocytes is blocked by pharmacological stabilization of its pseudokinase domain JS Tokarski, A Zupa-Fernandez, JA Tredup, K Pike, CY Chang, D Xie, ... Journal of Biological Chemistry 290 (17), 11061-11074, 2015 | 108 | 2015 |
| Optical sensor arrays for odor recognition DR Walt, T Dickinson, J White, J Kauer, S Johnson, H Engelhardt, J Sutter, ... Biosensors and Bioelectronics 13 (6), 697-699, 1998 | 106 | 1998 |
| Trends in kinase selectivity: insights for target class-focused library screening SL Posy, MA Hermsmeier, W Vaccaro, KH Ott, G Todderud, JS Lippy, ... Journal of medicinal chemistry 54 (1), 54-66, 2011 | 96 | 2011 |
| Molecular properties that influence the oral bioavailability of drug candidates DF Verber, SR Johnson, HY Cheng, BR Smith, KW Ward, KD Kopple J Med Chem 45 (12), 2615-2623, 2002 | 73 | 2002 |
| Phenoxypyrimidine inhibitors of p38α kinase: synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2 … JC Boehm, MJ Bower, TF Gallagher, S Kassis, SR Johnson, JL Adams Bioorganic & medicinal chemistry letters 11 (9), 1123-1126, 2001 | 51 | 2001 |
| A computational model for the prediction of aqueous solubility that includes crystal packing, intrinsic solubility, and ionization effects SR Johnson, XQ Chen, D Murphy, O Gudmundsson Molecular Pharmaceutics 4 (4), 513-523, 2007 | 48 | 2007 |
| Estimation of hERG inhibition of drug candidates using multivariate property and pharmacophore SAR SR Johnson, H Yue, ML Conder, H Shi, AM Doweyko, J Lloyd, ... Bioorganic & medicinal chemistry 15 (18), 6182-6192, 2007 | 42 | 2007 |
| Azabicyclic heterocycles as cannabinoid receptor modulators G Yu, WR Ewing, AB Mikkilineni, A Pendri, PM Sher, S Gerritz, ... US Patent 7,378,418, 2008 | 37 | 2008 |
| In silico prediction of biliary excretion of drugs in rats based on physicochemical properties G Luo, S Johnson, MM Hsueh, J Zheng, H Cai, B Xin, S Chong, K He, ... Drug metabolism and disposition 38 (3), 422-430, 2010 | 36 | 2010 |
| Prediction of the clearing temperatures of a series of liquid crystals from molecular structure SR Johnson, PC Jurs Chemistry of materials 11 (4), 1007-1023, 1999 | 36 | 1999 |
| Approaches for machine learning intermolecular interaction energies and application to energy components from symmetry adapted perturbation theory DP Metcalf, A Koutsoukas, SA Spronk, BL Claus, DA Loughney, ... The Journal of Chemical Physics 152 (7), 2020 | 35 | 2020 |
| Electrostatic-field and surface-shape similarity for virtual screening and pose prediction AE Cleves, SR Johnson, AN Jain Journal of computer-aided molecular design 33 (10), 865-886, 2019 | 33 | 2019 |
| Studies to further investigate the inhibition of human liver microsomal CYP2C8 by the acyl-β-glucuronide of gemfibrozil SM Jenkins, T Zvyaga, SR Johnson, J Hurley, A Wagner, R Burrell, ... Drug metabolism and disposition 39 (12), 2421-2430, 2011 | 32 | 2011 |
| Prediction of acute mammalian toxicity from molecular structure for a diverse set of substituted anilines using regression analysis and computational neural networks SR Johnson, PC Jurs Computer‐Assisted Lead Finding and Optimization: Current Tools for Medicinal …, 1997 | 26 | 1997 |
