A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase T Goris, AF Wait, M Saggu, J Fritsch, N Heidary, M Stein, I Zebger, ... Nature chemical biology 7 (5), 310-318, 2011 | 296 | 2011 |
Spectroscopic insights into the oxygen-tolerant membrane-associated [NiFe] hydrogenase of Ralstonia eutropha H16 M Saggu, I Zebger, M Ludwig, O Lenz, B Friedrich, P Hildebrandt, ... Journal of Biological Chemistry 284 (24), 16264-16276, 2009 | 143 | 2009 |
Experimental quantification of electrostatics in X–H··· π hydrogen bonds M Saggu, NM Levinson, SG Boxer Journal of the American Chemical Society 134 (46), 18986-18997, 2012 | 132 | 2012 |
Direct measurements of electric fields in weak OH··· π hydrogen bonds M Saggu, NM Levinson, SG Boxer Journal of the American Chemical Society 133 (43), 17414-17419, 2011 | 125 | 2011 |
Identification of subvisible particles in biopharmaceutical formulations using Raman spectroscopy provides insight into polysorbate 20 degradation pathway M Saggu, J Liu, A Patel Pharmaceutical research 32, 2877-2888, 2015 | 98 | 2015 |
A periplasmic aldehyde oxidoreductase represents the first molybdopterin cytosine dinucleotide cofactor containing molybdo‐flavoenzyme from Escherichia coli M Neumann, G Mittelstädt, C Iobbi‐Nivol, M Saggu, F Lendzian, ... The FEBS journal 276 (10), 2762-2774, 2009 | 95 | 2009 |
Trapping and Characterization of a Reaction Intermediate in Carbapenem Hydrolysis by B. cereus Metallo-β-lactamase MF Tioni, LI Llarrull, AA Poeylaut-Palena, MA Martí, M Saggu, ... Journal of the American Chemical Society 130 (47), 15852-15863, 2008 | 94 | 2008 |
Probing the Active Site of an O2‐Tolerant NAD+‐Reducing [NiFe]‐Hydrogenase from Ralstonia eutropha H16 by In Situ EPR and FTIR Spectroscopy M Horch, L Lauterbach, M Saggu, P Hildebrandt, F Lendzian, R Bittl, ... Angewandte Chemie International Edition 49 (43), 8026-8029, 2010 | 85 | 2010 |
Overexpression, isolation, and spectroscopic characterization of the bidirectional [NiFe] hydrogenase from Synechocystis sp. PCC 6803 F Germer, I Zebger, M Saggu, F Lendzian, R Schulz, J Appel Journal of Biological Chemistry 284 (52), 36462-36472, 2009 | 85 | 2009 |
Concerted action of two novel auxiliary proteins in assembly of the active site in a membrane-bound [NiFe] hydrogenase M Ludwig, T Schubert, I Zebger, N Wisitruangsakul, M Saggu, A Strack, ... Journal of Biological Chemistry 284 (4), 2159-2168, 2009 | 63 | 2009 |
Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1 S Schumann, M Terao, E Garattini, M Saggu, F Lendzian, P Hildebrandt, ... PloS one 4 (4), e5348, 2009 | 53 | 2009 |
The mechanism of assembly and cofactor insertion into Rhodobacter capsulatus xanthine dehydrogenase S Schumann, M Saggu, N Moller, SD Anker, F Lendzian, P Hildebrandt, ... Journal of Biological Chemistry 283 (24), 16602-16611, 2008 | 52 | 2008 |
Characterization and crystallization of mouse aldehyde oxidase 3: from mouse liver to Escherichia coli heterologous protein expression M Mahro, C Coelho, J Trincao, D Rodrigues, M Terao, E Garattini, ... Drug metabolism and disposition 39 (10), 1939-1945, 2011 | 41 | 2011 |
A random forest approach for counting silicone oil droplets and protein particles in antibody formulations using flow microscopy M Saggu, AR Patel, T Koulis Pharmaceutical research 34, 479-491, 2017 | 40 | 2017 |
Comparison of the membrane-bound [NiFe] hydrogenases from R. eutropha H16 and D. vulgaris Miyazaki F in the oxidized ready state by pulsed EPR M Saggu, C Teutloff, M Ludwig, M Brecht, ME Pandelia, O Lenz, ... Physical Chemistry Chemical Physics 12 (9), 2139-2148, 2010 | 37 | 2010 |
Substrate recognition of nitrogenase-like dark operative protochlorophyllide oxidoreductase from Prochlorococcus marinus MJ Bröcker, D Wätzlich, F Uliczka, S Virus, M Saggu, F Lendzian, ... Journal of Biological Chemistry 283 (44), 29873-29881, 2008 | 34 | 2008 |
Biosynthesis of (bacterio) chlorophylls: ATP-dependent transient subunit interaction and electron transfer of dark operative protochlorophyllide oxidoreductase MJ Bröcker, D Wätzlich, M Saggu, F Lendzian, J Moser, D Jahn Journal of Biological Chemistry 285 (11), 8268-8277, 2010 | 31 | 2010 |
Local and global electric field asymmetry in photosynthetic reaction centers M Saggu, SD Fried, SG Boxer The Journal of Physical Chemistry B 123 (7), 1527-1536, 2019 | 26 | 2019 |
Multi-attribute Raman spectroscopy (MARS) for monitoring product quality attributes in formulated monoclonal antibody therapeutics B Wei, N Woon, L Dai, R Fish, M Tai, W Handagama, A Yin, J Sun, ... MAbs 14 (1), 2007564, 2022 | 20 | 2022 |
A multicompany assessment of submicron particle levels by NTA and RMM in a wide range of late-phase clinical and commercial biotechnology-derived protein products M Hubert, DT Yang, SC Kwok, A Rios, TK Das, A Patel, K Wuchner, ... Journal of Pharmaceutical Sciences 109 (1), 830-844, 2020 | 20 | 2020 |