Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13329* | 2021 |
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019 | 569 | 2019 |
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) JE Burke, O Perisic, GR Masson, O Vadas, RL Williams Proceedings of the National Academy of Sciences 109 (38), 15259-15264, 2012 | 302 | 2012 |
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ... Science 350 (6257), aac7365, 2015 | 259 | 2015 |
The cargo receptor NDP52 initiates selective autophagy by recruiting the ULK complex to cytosol-invading bacteria BJ Ravenhill, KB Boyle, N von Muhlinen, CJ Ellison, GR Masson, ... Molecular cell 74 (2), 320-329. e6, 2019 | 258 | 2019 |
Activation of GCN2 by the ribosomal P-stalk AJ Inglis, GR Masson, S Shao, O Perisic, SH McLaughlin, RS Hegde, ... Proceedings of the National Academy of Sciences 116 (11), 4946-4954, 2019 | 171 | 2019 |
An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery GR Masson, ML Jenkins, JE Burke Expert opinion on drug discovery 12 (10), 981-994, 2017 | 155 | 2017 |
Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors JE Burke, AJ Inglis, O Perisic, GR Masson, SH McLaughlin, F Rutaganira, ... Science 344 (6187), 1035-1038, 2014 | 145 | 2014 |
Architecture of human Rag GTPase heterodimers and their complex with mTORC1 M Anandapadamanaban, GR Masson, O Perisic, A Berndt, J Kaufman, ... Science 366 (6462), 203-210, 2019 | 106 | 2019 |
Towards a model of GCN2 activation GR Masson Biochemical Society Transactions 47 (5), 1481-1488, 2019 | 103 | 2019 |
The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity GR Masson, O Perisic, JE Burke, RL Williams Biochemical Journal 473 (2), 135-144, 2016 | 84 | 2016 |
Regulation of PI3K by PKC and MARCKS: single-molecule analysis of a reconstituted signaling pathway BP Ziemba, JE Burke, G Masson, RL Williams, JJ Falke Biophysical journal 110 (8), 1811-1825, 2016 | 79 | 2016 |
Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex Y Ohashi, N Soler, M García Ortegón, L Zhang, ML Kirsten, O Perisic, ... Autophagy 12 (11), 2129-2144, 2016 | 68 | 2016 |
Single-molecule study reveals how receptor and ras synergistically activate PI3Kα and PIP3 signaling TC Buckles, BP Ziemba, GR Masson, RL Williams, JJ Falke Biophysical Journal 113 (11), 2396-2405, 2017 | 66 | 2017 |
PTEN regulates cilia through Dishevelled I Shnitsar, M Bashkurov, GR Masson, AA Ogunjimi, S Mosessian, ... Nature communications 6 (1), 8388, 2015 | 65 | 2015 |
Structural mechanisms of PTEN regulation GR Masson, RL Williams Cold Spring Harbor Perspectives in Medicine 10 (3), a036152, 2020 | 58 | 2020 |
A stay of execution: ATF4 regulation and potential outcomes for the integrated stress response G Neill, GR Masson Frontiers in Molecular Neuroscience 16, 1112253, 2023 | 54 | 2023 |
Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11 ML Fowler, JA McPhail, ML Jenkins, GR Masson, FU Rutaganira, ... Protein Science 25 (4), 826-839, 2016 | 47 | 2016 |
Membrane characteristics tune activities of endosomal and autophagic human VPS34 complexes Y Ohashi, S Tremel, GR Masson, L McGinney, J Boulanger, ... Elife 9, e58281, 2020 | 42 | 2020 |
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration GQ Gong, B Bilanges, B Allsop, GR Masson, V Roberton, T Askwith, ... Nature 618 (7963), 159-168, 2023 | 36 | 2023 |