| Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake W Zhang, D Hong, Y Zhou, Y Zhang, Q Shen, J Li, L Hu, J Li Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (10), 1505-1512, 2006 | 325 | 2006 |
| Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities YN Zhang, W Zhang, D Hong, L Shi, Q Shen, JY Li, J Li, LH Hu Bioorganic & medicinal chemistry 16 (18), 8697-8705, 2008 | 195 | 2008 |
| Bifunctional cinchona alkaloid thiourea catalyzed highly efficient, enantioselective aza‐henry reaction of cyclic trifluoromethyl ketimines: synthesis of anti‐HIV drug DPC 083 H Xie, Y Zhang, S Zhang, X Chen, W Wang Angewandte Chemie International Edition 49 (50), 11773-11776, 2011 | 147 | 2011 |
| Corosolic acid stimulates glucose uptake via enhancing insulin receptor phosphorylation L Shi, W Zhang, YY Zhou, YN Zhang, JY Li, LH Hu, J Li European journal of pharmacology 584 (1), 21-29, 2008 | 117 | 2008 |
| Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation Q Lv, Y Xing, J Liu, D Dong, Y Liu, H Qiao, Y Zhang, L Hu Acta Pharmaceutica Sinica B 11 (9), 2880-2899, 2021 | 104 | 2021 |
| Cu (II) catalyzed oxidation-[3+ 2] cycloaddition-aromatization cascade: Efficient synthesis of pyrrolo [2, 1-a] isoquinolines C Yu, Y Zhang, S Zhang, H Li, W Wang Chemical Communications 47 (3), 1036-1038, 2011 | 95 | 2011 |
| Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. YN Zhang, XG Zhong, ZP Zheng, XD Hu, JP Zuo, LH Hu Bioorganic & medicinal chemistry 15 (2), 988-996, 2007 | 89 | 2007 |
| Interplay of Direct Stereocontrol and Dynamic Kinetic Resolution in a Bifunctional Amine Thiourea Catalyzed Highly Enantioselective Cascade Michael–Michael Reaction C Yu, Y Zhang, A Song, Y Ji, W Wang Chemistry–A European Journal 3 (17), 770-774, 2011 | 80 | 2011 |
| Frenolicins C–G, Pyranonaphthoquinones from Streptomyces sp. RM-4-15 X Wang, KA Shaaban, SI Elshahawi, LV Ponomareva, M Sunkara, ... Journal of natural products 76 (8), 1441-1447, 2013 | 75 | 2013 |
| Diastereo-and enantioselective organocatalytic direct conjugate addition of γ-butenolide to chalcones Y Zhang, C Yu, Y Ji, W Wang Chemistry, an Asian journal 5 (6), 1303, 2010 | 71 | 2010 |
| Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions Z Gao, T Zhang, M Wu, Q Xiong, H Sun, Y Zhang, L Zu, W Wang, M Li Journal of Biological Chemistry 285 (36), 28322-28332, 2010 | 61 | 2010 |
| Nine New Dammarane Saponins from Gynostemma pentaphyllum F Yin, YN Zhang, ZY Yang, LH Hu Chemistry & Biodiversity 3 (7), 771-782, 2006 | 60 | 2006 |
| Anti-inflammatory effects of Z23 on LPS-induced inflammatory responses in RAW264. 7 macrophages XD Hu, Y Yang, XG Zhong, XH Zhang, YN Zhang, ZP Zheng, Y Zhou, ... Journal of ethnopharmacology 120 (3), 447-451, 2008 | 52 | 2008 |
| Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism Z Lin, Y Zhang, Y Zhang, H Shen, L Hu, H Jiang, X Shen Biochemical pharmacology 76 (10), 1251-1262, 2008 | 52 | 2008 |
| Catalytic enantioselective conjugate addition of fluorobis (phenylsulfonyl) methane to enals: synthesis of chiral monofluoromethyl compounds S Zhang, Y Zhang, Y Ji, H Li, W Wang Chemical communications, 4886-4888, 2009 | 50 | 2009 |
| Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6 KA Shaaban, MA Saunders, Y Zhang, T Tran, SI Elshahawi, ... Journal of natural products 80 (1), 2-11, 2017 | 49 | 2017 |
| Aryl hydrocarbon receptor deficiency in intestinal epithelial cells aggravates alcohol-related liver disease M Qian, J Liu, D Zhao, P Cai, C Pan, W Jia, Y Gao, Y Zhang, N Zhang, ... Cellular and molecular gastroenterology and hepatology 13 (1), 233-256, 2022 | 46 | 2022 |
| Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5–8 X Wang, AR Reynolds, SI Elshahawi, KA Shaaban, LV Ponomareva, ... Organic letters 17 (11), 2796-2799, 2015 | 46 | 2015 |
| Lindenane Sesquiterpene Dimers from Chloranthus fortunei XC Wang, YN Zhang, LL Wang, SP Ma, JH Liu, LH Hu Journal of natural products 71 (4), 674-677, 2008 | 46 | 2008 |
| Highly enantioselective Michael-cyclization cascade promoted by synergistic asymmetric aminocatalysis and Lewis acid catalysis C Yu, Y Zhang, S Zhang, J He, W Wang Tetrahedron Letters 51 (13), 1742-1744, 2010 | 44 | 2010 |
Jon S. ThorsonProfessor and Associate Dean for Research, University of Kentucky College of PharmacyVerified email at uky.edu