Articles with public access mandates - David R. SneadLearn more
Not available anywhere: 1
Scaling continuous API synthesis from milligram to kilogram: extending the enabling benefits of micro to the plant
M Berton, JM de Souza, I Abdiaj, DT McQuade, DR Snead
Journal of Flow Chemistry 10, 73-92, 2020
Mandates: Bill & Melinda Gates Foundation, US Department of Defense
Available somewhere: 23
On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
A Adamo, RL Beingessner, M Behnam, J Chen, TF Jamison, KF Jensen, ...
Science 352 (6281), 61-67, 2016
Mandates: US National Science Foundation, US Department of Energy, US National …
A concise route to MK-4482 (EIDD-2801) from cytidine
N Vasudevan, GP Ahlqvist, CP McGeough, DJ Paymode, FSP Cardoso, ...
Chemical Communications 56 (87), 13363-13364, 2020
Mandates: US National Science Foundation, Bill & Melinda Gates Foundation
Progress toward a large-scale synthesis of molnupiravir (MK-4482, EIDD-2801) from cytidine
GP Ahlqvist, CP McGeough, C Senanayake, JD Armstrong, A Yadaw, ...
ACS omega 6 (15), 10396-10402, 2021
Mandates: US National Science Foundation, Bill & Melinda Gates Foundation
Toward a practical, two-step process for molnupiravir: Direct hydroxamination of cytidine followed by selective esterification
DJ Paymode, N Vasudevan, S Ahmad, AL Kadam, FSP Cardoso, ...
Organic Process Research & Development 25 (8), 1822-1830, 2021
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Expanding access to remdesivir via an improved pyrrolotriazine synthesis: supply centered synthesis
DJ Paymode, FSP Cardoso, T Agrawal, JW Tomlin, DW Cook, JM Burns, ...
Organic Letters 22 (19), 7656-7661, 2020
Mandates: Bill & Melinda Gates Foundation
A high‐yielding synthesis of EIDD‐2801 from Uridine
A Steiner, D Znidar, SB Ötvös, DR Snead, D Dallinger, CO Kappe
European Journal of Organic Chemistry 2020 (43), 6736-6739, 2020
Mandates: Bill & Melinda Gates Foundation
A Concise Route to MK-4482 (EIDD-2801) from Cytidine: Part 2
V Gopalsamuthiram, C Williams, J Noble, TF Jamison, BF Gupton, ...
Synlett 32 (03), 326-328, 2021
Mandates: Bill & Melinda Gates Foundation
An efficient synthesis of tenofovir (PMPA): A key intermediate leading to tenofovir-based HIV medicines
BP Derstine, JW Tomlin, CL Peck, JP Dietz, BT Herrera, FSP Cardoso, ...
Organic Process Research & Development 24 (8), 1420-1427, 2020
Mandates: Bill & Melinda Gates Foundation
An economical route to lamivudine featuring a novel strategy for stereospecific assembly
DR Snead, DT McQuade, S Ahmad, R Krack, RW Stringham, JM Burns, ...
Organic Process Research & Development 24 (6), 1194-1198, 2020
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Toward a practical, nonenzymatic process for investigational COVID-19 antiviral molnupiravir from cytidine: Supply-centered synthesis
V Gopalsamuthiram, AL Kadam, JK Noble, DR Snead, C Williams, ...
Organic Process Research & Development 25 (12), 2679-2685, 2021
Mandates: Bill & Melinda Gates Foundation
Synthesis of an Oxathiolane drug substance intermediate guided by constraint-driven innovation
K Kashinath, DR Snead, JM Burns, RW Stringham, BF Gupton, ...
Organic Process Research & Development 24 (10), 2266-2270, 2020
Mandates: Bill & Melinda Gates Foundation
Oxidative rearrangement via 1, 2-Aryl migration using hydroxy (tosyloxy) iodobenzene in a polar aprotic solvent
R Kamal, V Kumar, R Kumar, S Saini, R Kumar
Synlett 31 (10), 959-964, 2020
Mandates: Department of Science & Technology, India
Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir
S Roy, A Yadaw, S Roy, G Sirasani, A Gangu, JD Brown, JD Armstrong III, ...
Organic Process Research & Development 26 (1), 82-90, 2022
Mandates: Bill & Melinda Gates Foundation
Application of vinamidinium salt chemistry for a palladium free synthesis of anti-malarial MMV048: A “bottom-up” approach
DJ Paymode, L Chang, D Chen, B Wang, K Kashinath, ...
Organic Letters 23 (14), 5400-5404, 2021
Mandates: Bill & Melinda Gates Foundation
A Continuous Flow Sulfuryl Chloride-Based Reaction—Synthesis of a Key Intermediate in a New Route toward Emtricitabine and Lamivudine
JM de Souza, M Berton, DR Snead, DT McQuade
Organic Process Research & Development 24 (10), 2271-2280, 2020
Mandates: Bill & Melinda Gates Foundation, US Department of Defense
Diastereoselectivity is in the details: minor changes yield major improvements to the synthesis of bedaquiline
SJ Mear, T Lucas, GP Ahlqvist, JMS Robey, JP Dietz, PV Khairnar, ...
Chemistry–A European Journal 28 (47), e202201311, 2022
Mandates: US National Science Foundation, Bill & Melinda Gates Foundation
Short and Efficient Synthesis of the Antituberculosis Agent Pretomanid from (R)-Glycidol
T Lucas, JP Dietz, FSP Cardoso, DR Snead, RC Nelson, KO Donsbach, ...
Organic Process Research & Development 27 (9), 1641-1651, 2023
Mandates: Bill & Melinda Gates Foundation
Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro [3.3] heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223
FSP Cardoso, AL Kadam, RC Nelson, JW Tomlin, D Dahal, CS Kuehner, ...
Organic Process Research & Development 27 (7), 1390-1399, 2023
Mandates: Bill & Melinda Gates Foundation
A Practical and Economical Route to (S)-Glycidyl Pivalate
JM Noble, L Chang, D Chen, B Wang, RN Dominey, DW Cook, JM Burns, ...
SynOpen 6 (04), 258-262, 2022
Mandates: Bill & Melinda Gates Foundation
Publication and funding information is determined automatically by a computer program