Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity F Weinberg, R Hamanaka, WW Wheaton, S Weinberg, J Joseph, M Lopez, ... Proceedings of the National Academy of Sciences 107 (19), 8788-8793, 2010 | 1852 | 2010 |
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis WW Wheaton, SE Weinberg, RB Hamanaka, S Soberanes, LB Sullivan, ... elife 3, e02242, 2014 | 1150 | 2014 |
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes RB Hamanaka, NS Chandel Trends in biochemical sciences 35 (9), 505-513, 2010 | 1130 | 2010 |
Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis PA Reyfman, JM Walter, N Joshi, KR Anekalla, AC McQuattie-Pimentel, ... American journal of respiratory and critical care medicine 199 (12), 1517-1536, 2019 | 1088 | 2019 |
Mitochondrial complex III ROS regulate adipocyte differentiation KV Tormos, E Anso, RB Hamanaka, J Eisenbart, J Joseph, ... Cell metabolism 14 (4), 537-544, 2011 | 709 | 2011 |
Particulate matter air pollution: effects on the cardiovascular system RB Hamanaka, GM Mutlu Frontiers in endocrinology 9, 680, 2018 | 563 | 2018 |
The role of nuclear lamin B1 in cell proliferation and senescence T Shimi, V Butin-Israeli, SA Adam, RB Hamanaka, AE Goldman, CA Lucas, ... Genes & development 25 (24), 2579-2593, 2011 | 553 | 2011 |
Targeting glucose metabolism for cancer therapy RB Hamanaka, NS Chandel Journal of Experimental Medicine 209 (2), 211-215, 2012 | 457 | 2012 |
Mitochondrial reactive oxygen species regulate hypoxic signaling RB Hamanaka, NS Chandel Current opinion in cell biology 21 (6), 894-899, 2009 | 364 | 2009 |
PERK and GCN2 contribute to eIF2α phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway RB Hamanaka, BS Bennett, SB Cullinan, JA Diehl Molecular biology of the cell 16 (12), 5493-5501, 2005 | 326 | 2005 |
Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development RB Hamanaka, A Glasauer, P Hoover, S Yang, H Blatt, AR Mullen, ... Science signaling 6 (261), ra8-ra8, 2013 | 306 | 2013 |
Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome EA Mutlu, IY Comba, T Cho, PA Engen, C Yazıcı, S Soberanes, ... Environmental pollution 240, 817-830, 2018 | 219 | 2018 |
Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation GA Gusarova, HE Trejo, LA Dada, A Briva, LC Welch, RB Hamanaka, ... Molecular and cellular biology 31 (17), 3546-3556, 2011 | 185 | 2011 |
Warburg effect and redox balance RB Hamanaka, NS Chandel Science 334 (6060), 1219-1220, 2011 | 173 | 2011 |
Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor J Liu, WC HuangFu, KGS Kumar, J Qian, JP Casey, RB Hamanaka, ... Cell host & microbe 5 (1), 72-83, 2009 | 162 | 2009 |
HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium D Wu, RT Huang, RB Hamanaka, M Krause, MJ Oh, CH Kuo, ... Elife 6, e25217, 2017 | 151 | 2017 |
Transforming growth factor (TGF)-β promotes de novo serine synthesis for collagen production R Nigdelioglu, RB Hamanaka, AY Meliton, E O'Leary, LJ Witt, T Cho, ... Journal of Biological Chemistry 291 (53), 27239-27251, 2016 | 141 | 2016 |
Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest F Zhang, RB Hamanaka, E Bobrovnikova-Marjon, JD Gordan, MS Dai, ... Journal of Biological Chemistry 281 (40), 30036-30045, 2006 | 138 | 2006 |
Glutamine metabolism is required for collagen protein synthesis in lung fibroblasts RB Hamanaka, EM O’Leary, LJ Witt, Y Tian, GA Gökalp, AY Meliton, ... American journal of respiratory cell and molecular biology 61 (5), 597-606, 2019 | 127 | 2019 |
PERK-dependent regulation of IAP translation during ER stress RB Hamanaka, E Bobrovnikova-Marjon, X Ji, SA Liebhaber, JA Diehl Oncogene 28 (6), 910-920, 2009 | 121 | 2009 |