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Sivareddy Kotla
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ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation
S Kotla, NK Singh, GN Rao
Redox Biology 11, 350-364, 2017
722017
The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis
S Kotla, NK Singh, MR Heckle, GJ Tigyi, GN Rao
Science signaling 6 (293), ra83-ra83, 2013
712013
Senescent phenotype induced by p90RSK-NRF2 signaling sensitizes monocytes and macrophages to oxidative stress in HIV-positive individuals: Implications for atherogenesis
MV Singh, S Kotla, NT Le, K Ae Ko, KS Heo, Y Wang, Y Fujii, H Thi Vu, ...
Circulation 139 (9), 1199-1216, 2019
572019
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis
J Abe, KA Ko, S Kotla, Y Wang, J Paez-Mayorga, IJ Shin, M Imanishi, ...
JCI insight 4 (7), 2019
452019
Senescence-associated secretory phenotype as a hinge between cardiovascular diseases and cancer
P Banerjee, S Kotla, L Reddy Velatooru, RJ Abe, EA Davis, JP Cooke, ...
Frontiers in Cardiovascular Medicine 8, 763930, 2021
432021
Protein kinase N1 is a novel substrate of NFATc1-mediated cyclin D1-CDK6 activity and modulates vascular smooth muscle cell division and migration leading to inward blood …
NK Singh, V Kundumani-Sridharan, S Kumar, SK Verma, S Kotla, H Mukai, ...
Journal of Biological Chemistry 287 (43), 36291-36304, 2012
412012
Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2–interacting protein
S Kotla, HT Vu, KA Ko, Y Wang, M Imanishi, KS Heo, Y Fujii, TN Thomas, ...
JCI insight 4 (9), 2019
392019
ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15 (S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formation
S Kotla, NK Singh, JG Traylor Jr, AW Orr, GN Rao
Free Radical Biology and Medicine 76, 147-162, 2014
332014
Cyclic AMP response element binding protein mediates pathological retinal neovascularization via modulating DLL4-NOTCH1 signaling
NK Singh, S Kotla, R Kumar, GN Rao
EBioMedicine 2 (11), 1767-1784, 2015
312015
Ponatinib activates an inflammatory response in endothelial cells via ERK5 SUMOylation
J Paez-Mayorga, AL Chen, S Kotla, Y Tao, RJ Abe, ED He, BP Danysh, ...
Frontiers in cardiovascular medicine 5, 125, 2018
292018
PLCβ3 mediates cortactin interaction with WAVE2 in MCP1-induced actin polymerization and cell migration
J Janjanam, GK Chandaka, S Kotla, GN Rao
Molecular biology of the cell 26 (25), 4589-4606, 2015
282015
Single‐cell RNA sequencing analysis of SARS‐CoV‐2 entry receptors in human organoids
R Mahalingam, P Dharmalingam, A Santhanam, S Kotla, G Davuluri, ...
Journal of cellular physiology 236 (4), 2950-2958, 2021
272021
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice
NK Singh, S Kotla, E Dyukova, JG Traylor Jr, AW Orr, J Chernoff, ...
Nature communications 6 (1), 7450, 2015
262015
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent …
S Kotla, A Zhang, M Imanishi, KA Ko, SH Lin, YJ Gi, M Moczygemba, ...
Redox Biology 47, 102132, 2021
242021
Ionizing radiation induces endothelial inflammation and apoptosis via p90RSK-mediated ERK5 S496 phosphorylation
HT Vu, S Kotla, KA Ko, Y Fujii, Y Tao, J Medina, T Thomas, M Hada, ...
Frontiers in cardiovascular medicine 5, 23, 2018
242018
Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase
S Kotla, NT Le, HT Vu, KA Ko, YJ Gi, TN Thomas, C Giancursio, AJ Lusis, ...
Metabolism 100, 153962, 2019
212019
DNA vaccine (P1-2A-3C-pCDNA) co-administered with Bovine IL-18 gives protective immune response against Foot and Mouth Disease in cattle
S Kotla, BS Vishanath, HJ Dechamma, K Ganesh, VVS Suryanarayana, ...
Veterinary Microbiology 193, 106-115, 2016
162016
Cationic microparticle [poly(d,l‐lactide‐co‐glycolide)]‐coated DNA vaccination induces a long‐term immune response against foot and mouth disease in guinea pigs
KS Reddy, BR Rashmi, HJ Dechamma, S Gopalakrishna, N Banumathi, ...
The journal of gene medicine 14 (5), 348-352, 2012
162012
Disturbed flow-induced FAK K152 SUMOylation initiates the formation of pro-inflammation positive feedback loop by inducing reactive oxygen species production in endothelial cells
LR Velatooru, RJ Abe, M Imanishi, YJ Gi, KA Ko, KS Heo, K Fujiwara, ...
Free Radical Biology and Medicine 177, 404-418, 2021
142021
An ERK5-NRF2 axis mediates senescence-associated stemness and atherosclerosis
J Abe, M Imanishi, S Li, A Zhang, KA Ko, VSK Samanthapudi, LL Lee, ...
Circulation research 133 (1), 25-44, 2023
132023
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