ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation S Kotla, NK Singh, GN Rao Redox Biology 11, 350-364, 2017 | 72 | 2017 |
The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis S Kotla, NK Singh, MR Heckle, GJ Tigyi, GN Rao Science signaling 6 (293), ra83-ra83, 2013 | 71 | 2013 |
Senescent phenotype induced by p90RSK-NRF2 signaling sensitizes monocytes and macrophages to oxidative stress in HIV-positive individuals: Implications for atherogenesis MV Singh, S Kotla, NT Le, K Ae Ko, KS Heo, Y Wang, Y Fujii, H Thi Vu, ... Circulation 139 (9), 1199-1216, 2019 | 57 | 2019 |
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis J Abe, KA Ko, S Kotla, Y Wang, J Paez-Mayorga, IJ Shin, M Imanishi, ... JCI insight 4 (7), 2019 | 45 | 2019 |
Senescence-associated secretory phenotype as a hinge between cardiovascular diseases and cancer P Banerjee, S Kotla, L Reddy Velatooru, RJ Abe, EA Davis, JP Cooke, ... Frontiers in Cardiovascular Medicine 8, 763930, 2021 | 43 | 2021 |
Protein kinase N1 is a novel substrate of NFATc1-mediated cyclin D1-CDK6 activity and modulates vascular smooth muscle cell division and migration leading to inward blood … NK Singh, V Kundumani-Sridharan, S Kumar, SK Verma, S Kotla, H Mukai, ... Journal of Biological Chemistry 287 (43), 36291-36304, 2012 | 41 | 2012 |
Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2–interacting protein S Kotla, HT Vu, KA Ko, Y Wang, M Imanishi, KS Heo, Y Fujii, TN Thomas, ... JCI insight 4 (9), 2019 | 39 | 2019 |
ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15 (S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formation S Kotla, NK Singh, JG Traylor Jr, AW Orr, GN Rao Free Radical Biology and Medicine 76, 147-162, 2014 | 33 | 2014 |
Cyclic AMP response element binding protein mediates pathological retinal neovascularization via modulating DLL4-NOTCH1 signaling NK Singh, S Kotla, R Kumar, GN Rao EBioMedicine 2 (11), 1767-1784, 2015 | 31 | 2015 |
Ponatinib activates an inflammatory response in endothelial cells via ERK5 SUMOylation J Paez-Mayorga, AL Chen, S Kotla, Y Tao, RJ Abe, ED He, BP Danysh, ... Frontiers in cardiovascular medicine 5, 125, 2018 | 29 | 2018 |
PLCβ3 mediates cortactin interaction with WAVE2 in MCP1-induced actin polymerization and cell migration J Janjanam, GK Chandaka, S Kotla, GN Rao Molecular biology of the cell 26 (25), 4589-4606, 2015 | 28 | 2015 |
Single‐cell RNA sequencing analysis of SARS‐CoV‐2 entry receptors in human organoids R Mahalingam, P Dharmalingam, A Santhanam, S Kotla, G Davuluri, ... Journal of cellular physiology 236 (4), 2950-2958, 2021 | 27 | 2021 |
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice NK Singh, S Kotla, E Dyukova, JG Traylor Jr, AW Orr, J Chernoff, ... Nature communications 6 (1), 7450, 2015 | 26 | 2015 |
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent … S Kotla, A Zhang, M Imanishi, KA Ko, SH Lin, YJ Gi, M Moczygemba, ... Redox Biology 47, 102132, 2021 | 24 | 2021 |
Ionizing radiation induces endothelial inflammation and apoptosis via p90RSK-mediated ERK5 S496 phosphorylation HT Vu, S Kotla, KA Ko, Y Fujii, Y Tao, J Medina, T Thomas, M Hada, ... Frontiers in cardiovascular medicine 5, 23, 2018 | 24 | 2018 |
Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase S Kotla, NT Le, HT Vu, KA Ko, YJ Gi, TN Thomas, C Giancursio, AJ Lusis, ... Metabolism 100, 153962, 2019 | 21 | 2019 |
DNA vaccine (P1-2A-3C-pCDNA) co-administered with Bovine IL-18 gives protective immune response against Foot and Mouth Disease in cattle S Kotla, BS Vishanath, HJ Dechamma, K Ganesh, VVS Suryanarayana, ... Veterinary Microbiology 193, 106-115, 2016 | 16 | 2016 |
Cationic microparticle [poly(d,l‐lactide‐co‐glycolide)]‐coated DNA vaccination induces a long‐term immune response against foot and mouth disease in guinea pigs KS Reddy, BR Rashmi, HJ Dechamma, S Gopalakrishna, N Banumathi, ... The journal of gene medicine 14 (5), 348-352, 2012 | 16 | 2012 |
Disturbed flow-induced FAK K152 SUMOylation initiates the formation of pro-inflammation positive feedback loop by inducing reactive oxygen species production in endothelial cells LR Velatooru, RJ Abe, M Imanishi, YJ Gi, KA Ko, KS Heo, K Fujiwara, ... Free Radical Biology and Medicine 177, 404-418, 2021 | 14 | 2021 |
An ERK5-NRF2 axis mediates senescence-associated stemness and atherosclerosis J Abe, M Imanishi, S Li, A Zhang, KA Ko, VSK Samanthapudi, LL Lee, ... Circulation research 133 (1), 25-44, 2023 | 13 | 2023 |