Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA L Warren, PD Manos, T Ahfeldt, YH Loh, H Li, F Lau, W Ebina, PK Mandal, ... Cell stem cell 7 (5), 618-630, 2010 | 3429 | 2010 |
Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging LS Justine D. Miller, Yosif M. Ganat, Sarah Cell Stem Cell 13 (6), 691-705, 2013 | 807 | 2013 |
Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9 Cell Stem Cell 15 (5), 643–652, 2014 | 611 | 2014 |
Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors J Riddell, R Gazit, BS Garrison, G Guo, A Saadatpour, PK Mandal, ... Cell 157 (3), 549-564, 2014 | 380 | 2014 |
Reprogramming human fibroblasts to pluripotency using modified mRNA PKM DJ Rossi Nature Protocols 8 (3), 568–582, 2013 | 256* | 2013 |
System xc− and thioredoxin reductase 1 cooperatively rescue glutathione deficiency PK Mandal, A Seiler, T Perisic, P Kölle, AB Canak, H Förster, N Weiss, ... Journal of Biological Chemistry 285 (29), 22244-22253, 2010 | 254 | 2010 |
DNA damage response in adult stem cells: pathways and consequences PK Mandal, C Blanpain, DJ Rossi Nature Reviews Molecular Cell Biology 12 (3), 198-202, 2011 | 218 | 2011 |
Fgd5 identifies hematopoietic stem cells in the murine bone marrow RDJ Gazit R, Mandal PK, Ebina W, Ben-Zvi A, Nombela-Arrieta C, Silberstein LE Journal of experimental medicine 211 (7), 1315-31, 2014 | 204 | 2014 |
Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation PK Mandal, M Schneider, P Kölle, P Kuhlencordt, H Förster, H Beck, ... Cancer research 70 (22), 9505-9514, 2010 | 155 | 2010 |
Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing BS Paulsen, PK Mandal, RL Frock, B Boyraz, R Yadav, S Upadhyayula, ... Nature biomedical engineering 1 (11), 878-888, 2017 | 109 | 2017 |
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling M Dagnell, J Frijhoff, I Pader, M Augsten, B Boivin, J Xu, PK Mandal, ... Proceedings of the National Academy of Sciences 110 (33), 13398-13403, 2013 | 107 | 2013 |
Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging P Säwen, M Eldeeb, E Erlandsson, TA Kristiansen, C Laterza, Z Kokaia, ... Elife 7, e41258, 2018 | 99 | 2018 |
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection J Horstkotte, T Perisic, M Schneider, P Lange, M Schroeder, C Kiermayer, ... Circulation 124 (25), 2892-2902, 2011 | 86 | 2011 |
Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity M Schneider, M Wortmann, PK Mandal, W Arpornchayanon, K Jannasch, ... Neoplasia 12 (3), 254-263, 2010 | 80 | 2010 |
Mitotic history reveals distinct stem cell populations and their contributions to hematopoiesis P Säwén, S Lang, P Mandal, DJ Rossi, S Soneji, D Bryder Cell reports 14 (12), 2809-2818, 2016 | 77 | 2016 |
A common origin for B-1a and B-2 lymphocytes in clonal pre-hematopoietic stem cells BK Hadland, B Varnum-Finney, PK Mandal, DJ Rossi, MG Poulos, ... Stem cell reports 8 (6), 1563-1572, 2017 | 58 | 2017 |
Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2 X Peng, PK Mandal, VO Kaminskyy, A Lindqvist, M Conrad, ESJ Arnér Cell death & disease 5 (5), e1235-e1235, 2014 | 34 | 2014 |
Genome Editing for Human Gene Therapy. TB Meissner, PK Mandal, LM Ferreira, DJ Rossi, CA Cowan Methods in enzymology 546, 273-295, 2014 | 33 | 2014 |
DNA-Damage-Induced Differentiation in Hematopoietic Stem Cells PK Mandal, DJ Rossi Cell 148 (5), 847-848, 2012 | 29 | 2012 |
Viability and DNA damage responses of TPPII-deficient Myc-and Ras-transformed fibroblasts C Tsurumi, E Firat, S Gaedicke, J Huai, PK Mandal, G Niedermann Biochemical and biophysical research communications 386 (4), 563-568, 2009 | 10 | 2009 |