| Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4 Y Li, R Si, Y Feng, HH Chen, L Zou, E Wang, M Zhang, HS Warren, ... Journal of Biological Chemistry 286 (36), 31308-31319, 2011 | 171 | 2011 |
| Role of Extracellular RNA and TLR3‐Trif Signaling in Myocardial Ischemia–Reperfusion Injury C Chen, Y Feng, L Zou, L Wang, HH Chen, JY Cai, JM Xu, DE Sosnovik, ... Journal of the American Heart Association 3 (1), e000683, 2014 | 166 | 2014 |
| Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase Y Liu, A Asnani, L Zou, VL Bentley, M Yu, Y Wang, G Dellaire, KS Sarkar, ... Science translational medicine 6 (266), 266ra170-266ra170, 2014 | 143 | 2014 |
| Enhanced loading of functional miRNA cargo via pH gradient modification of extracellular vesicles A Jeyaram, TN Lamichhane, S Wang, L Zou, E Dahal, SM Kronstadt, ... Molecular Therapy 28 (3), 975-985, 2020 | 128 | 2020 |
| Circulating plasma extracellular vesicles from septic mice induce inflammation via MicroRNA-and TLR7-dependent mechanisms J Xu, Y Feng, A Jeyaram, SM Jay, L Zou, W Chao The Journal of Immunology 201 (11), 3392-3400, 2018 | 104 | 2018 |
| Toll-like receptor 2 plays a critical role in cardiac dysfunction during polymicrobial sepsis L Zou, Y Feng, YJ Chen, R Si, S Shen, Q Zhou, F Ichinose, ... Critical care medicine 38 (5), 1335-1342, 2010 | 102 | 2010 |
| Complement Factor B Is the Downstream Effector of TLRs and Plays an Important Role in a Mouse Model of Severe Sepsis L Zou, Y Feng, Y Li, M Zhang, C Chen, J Cai, Y Gong, L Wang, ... The Journal of Immunology 191 (11), 5625-5635, 2013 | 99 | 2013 |
| Extracellular microRNAs induce potent innate immune responses via TLR7/MyD88-dependent mechanisms Y Feng, L Zou, D Yan, H Chen, G Xu, W Jian, P Cui, W Chao The Journal of Immunology 199 (6), 2106-2117, 2017 | 84 | 2017 |
| Validation of noninvasive measurements of cardiac output in mice using echocardiography F Tournoux, B Petersen, H Thibault, L Zou, MJ Raher, B Kurtz, EF Halpern, ... Journal of the American Society of Echocardiography 24 (4), 465-470, 2011 | 79 | 2011 |
| Differences in left ventricular twist related to age: speckle tracking echocardiographic data for healthy volunteers from neonate to age 70 years Y Zhang, Q Zhou, D Pu, L Zou, Y Tan Echocardiography 27 (10), 1205-1210, 2010 | 75 | 2010 |
| Assessment of the fetal thymus by two‐and three‐dimensional ultrasound during normal human gestation and in fetuses with congenital heart defects L Li, MO Bahtiyar, CS Buhimschi, L Zou, QC Zhou, JA Copel Ultrasound in Obstetrics & Gynecology 37 (4), 404-409, 2011 | 70 | 2011 |
| Cardiac RNA induces inflammatory responses in cardiomyocytes and immune cells via Toll-like receptor 7 signaling Y Feng, H Chen, J Cai, L Zou, D Yan, G Xu, D Li, W Chao Journal of Biological Chemistry 290 (44), 26688-26698, 2015 | 66 | 2015 |
| MyD88 and Trif signaling play distinct roles in cardiac dysfunction and mortality during endotoxin shock and polymicrobial sepsis Y Feng, L Zou, M Zhang, Y Li, C Chen, W Chao The Journal of the American Society of Anesthesiologists 115 (3), 555-567, 2011 | 64 | 2011 |
| Toll-like Receptor 4 Signaling Confers Cardiac Protection against Ischemic Injury via Inducible Nitric Oxide Synthase- and Soluble Guanylate Cyclase-dependent … E Wang, Y Feng, M Zhang, L Zou, Y Li, ES Buys, P Huang, P Brouckaert, ... The Journal of the American Society of Anesthesiologists 114 (3), 603-613, 2011 | 54 | 2011 |
| Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression PY Sips, T Irie, L Zou, S Shinozaki, M Sakai, N Shimizu, R Nguyen, ... American Journal of Physiology-Heart and Circulatory Physiology 304 (8 …, 2013 | 50 | 2013 |
| Bone marrow MyD88 signaling modulates neutrophil function and ischemic myocardial injury Y Feng, L Zou, R Si, Y Nagasaka, W Chao American Journal of Physiology-Cell Physiology 299 (4), C760-C769, 2010 | 49 | 2010 |
| Nonhematopoietic toll-like receptor 2 contributes to neutrophil and cardiac function impairment during polymicrobial sepsis L Zou, Y Feng, M Zhang, Y Li, W Chao Shock 36 (4), 370-380, 2011 | 43 | 2011 |
| Toll-like receptor 4 is essential to preserving cardiac function and survival in low-grade polymicrobial sepsis M Zhang, L Zou, Y Feng, YJ Chen, Q Zhou, F Ichinose, W Chao Anesthesiology 121 (6), 1270-1280, 2014 | 41 | 2014 |
| Splenic RNA and microRNA mimics promote complement factor B production and alternative pathway activation via innate immune signaling L Zou, Y Feng, G Xu, W Jian, W Chao The Journal of Immunology 196 (6), 2788-2798, 2016 | 39 | 2016 |
| Targeting toll-like receptors in sepsis: from bench to clinical trials F Chen, L Zou, B Williams, W Chao Antioxidants & Redox Signaling 35 (15), 1324-1339, 2021 | 34 | 2021 |
Wei Chao, MD, PhDCo-Director, Center for Shock, Trauma & Anesthesiology Research, University of Maryland School ofVerified email at som.umaryland.edu