Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ... Cell 185 (14), 2559-2575. e28, 2022 | 312 | 2022 |
Integrator recruits protein phosphatase 2A to prevent pause release and facilitate transcription termination KL Huang, D Jee, CB Stein, ND Elrod, T Henriques, LG Mascibroda, ... Molecular cell 80 (2), 345-358. e9, 2020 | 134 | 2020 |
Integrator subunit 4 is a ‘Symplekin-like’scaffold that associates with INTS9/11 to form the Integrator cleavage module TR Albrecht, SP Shevtsov, Y Wu, LG Mascibroda, NJ Peart, KL Huang, ... Nucleic acids research 46 (8), 4241-4255, 2018 | 80 | 2018 |
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex LG Mascibroda, M Shboul, ND Elrod, L Colleaux, H Hamamy, KL Huang, ... Nature communications 13 (1), 6054, 2022 | 18 | 2022 |
INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly LG Mascibroda, M Shboul, ND Elrod, L Colleaux, H Hamamy, KL Huang, ... bioRxiv, 2020.07. 20.209130, 2020 | 11 | 2020 |
Explorative Study on Isolation and Characterization of a Microviridae G4 Bacteriophage, EMCL318, against Multi-Drug-resistant Escherichia coli 15-318 S Ghosh, E Persad, TY Shiue, C Lam, A Islam, LG Mascibroda, ... Antibiotics 7 (4), 92, 2018 | 6 | 2018 |
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines G Nishiguchi, LG Mascibroda, SM Young, EA Caine, S Abdelhamed, ... Nature Communications 15 (1), 482, 2024 | 5 | 2024 |
Rationally Designed Potent and Selective CK1α Degraders Exert Antiproliferative Activity Against a Broad Range of Human Cancer Cell Lines Z Rankovic, G Nishiguchi, S Abdelhamed, S Young, E Caine, ... | 1 | 2023 |
Structural insights into targeted degradation of casein kinase 1-α S Young, G Nishiguchi, S Abdelhamed, E Caine, L Mascibroda, ... Biophysical Journal 123 (3), 185a, 2024 | | 2024 |