Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions G Pearson, F Robinson, T Beers Gibson, B Xu, M Karandikar, K Berman, ... Endocrine reviews 22 (2), 153-183, 2001 | 5777 | 2001 |
MAP kinases Z Chen, TB Gibson, F Robinson, L Silvestro, G Pearson, B Xu, A Wright, ... Chemical reviews 101 (8), 2449-2476, 2001 | 1352 | 2001 |
New insights into the control of MAP kinase pathways J English, G Pearson, J Wilsbacher, J Swantek, M Karandikar, S Xu, ... Experimental cell research 253 (1), 255-270, 1999 | 585 | 1999 |
Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy RL Nicol, N Frey, G Pearson, M Cobb, J Richardson, EN Olson The EMBO Journal, 2001 | 364 | 2001 |
Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases JM English, G Pearson, R Baer, MH Cobb Journal of Biological Chemistry 273 (7), 3854-3860, 1998 | 223 | 1998 |
An epigenetically distinct breast cancer cell subpopulation promotes collective invasion JM Westcott, AM Prechtl, EA Maine, TT Dang, MA Esparza, H Sun, Y Zhou, ... The Journal of clinical investigation 125 (5), 1927-1943, 2015 | 194 | 2015 |
Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control JM English, G Pearson, T Hockenberry, L Shivakumar, MA White, ... Journal of Biological Chemistry 274 (44), 31588-31592, 1999 | 178 | 1999 |
ERK5 and ERK2 cooperate to regulate NF-κB and cell transformation G Pearson, JM English, MA White, MH Cobb Journal of Biological Chemistry 276 (11), 7927-7931, 2001 | 166 | 2001 |
Control of invasion by epithelial-to-mesenchymal transition programs during metastasis GW Pearson Journal of clinical medicine 8 (5), 646, 2019 | 151 | 2019 |
Secondary dimerization between members of the epidermal growth factor receptor family DC Gamett, G Pearson, RA Cerione, I Friedberg Journal of Biological Chemistry 272 (18), 12052-12056, 1997 | 141 | 1997 |
Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation G Pearson, R Bumeister, DO Henry, MH Cobb, MA White Journal of Biological Chemistry 275 (48), 37303-37306, 2000 | 98 | 2000 |
ΔNp63α promotes breast cancer cell motility through the selective activation of components of the epithelial-to-mesenchymal transition program TT Dang, MA Esparza, EA Maine, JM Westcott, GW Pearson Cancer research 75 (18), 3925-3935, 2015 | 95 | 2015 |
The MAP kinase ERK5 binds to and phosphorylates p90 RSK A Ranganathan, GW Pearson, CA Chrestensen, TW Sturgill, MH Cobb Archives of biochemistry and biophysics 449 (1-2), 8-16, 2006 | 90 | 2006 |
The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion EA Maine, JM Westcott, AM Prechtl, TT Dang, AW Whitehurst, ... Oncotarget 7 (12), 14708, 2016 | 78 | 2016 |
Breast cancer subtype-specific interactions with the microenvironment dictate mechanisms of invasion TT Dang, AM Prechtl, GW Pearson Cancer research 71 (21), 6857-6866, 2011 | 78 | 2011 |
Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells GW Pearson, T Hunter The Journal of cell biology 179 (7), 1555, 2007 | 74 | 2007 |
Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK HA Dbouk, LM Weil, GKS Perera, MT Dellinger, G Pearson, RA Brekken, ... Proceedings of the National Academy of Sciences 111 (45), 15999-16004, 2014 | 66 | 2014 |
ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion TT Dang, JM Westcott, EA Maine, M Kanchwala, C Xing, GW Pearson Oncotarget 7 (19), 28592, 2016 | 59 | 2016 |
Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signals GW Pearson, S Earnest, MH Cobb Molecular and cellular biology 26 (8), 3039-3047, 2006 | 49 | 2006 |
WNK1 enhances migration and invasion in breast cancer models AB Jaykumar, JU Jung, PK Parida, TT Dang, C Wichaidit, AR Kannangara, ... Molecular cancer therapeutics 20 (10), 1800-1808, 2021 | 36 | 2021 |