MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-κB pathway M Kumar, SK Sahu, R Kumar, A Subuddhi, RK Maji, K Jana, P Gupta, ... Cell host & microbe 17 (3), 345-356, 2015 | 252 | 2015 |
Deamidation of Cdc42 and Rac by Escherichia coliCytotoxic Necrotizing Factor 1: Activation of c-Jun N-Terminal Kinase in HeLa Cells M Lerm, J Selzer, A Hoffmeyer, UR Rapp, K Aktories, G Schmidt Infection and immunity 67 (2), 496-503, 1999 | 217 | 1999 |
The Rho-deamidating Cytotoxic Necrotizing Factor 1 fromEscherichia coli Possesses Transglutaminase Activity: CYSTEINE 866 AND HISTIDINE 881 ARE ESSENTIAL FOR ENZYME ACTIVITY G Schmidt, M Lerm, K Aktories Journal of Biological Chemistry 273 (22), 13669-13674, 1998 | 186 | 1998 |
Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men I Schoultz, D Verma, J Halfvarsson, L Törkvist, M Fredrikson, U Sjöqvist, ... Official journal of the American College of Gastroenterology| ACG 104 (5 …, 2009 | 181 | 2009 |
The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production D Verma, E Särndahl, H Andersson, P Eriksson, M Fredrikson, JI Jönsson, ... PloS one 7 (4), e34977, 2012 | 168 | 2012 |
Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1-and cathepsin B-independent necrosis A Welin, D Eklund, O Stendahl, M Lerm PloS one 6 (5), e20302, 2011 | 162 | 2011 |
Incorporation of Mycobacterium tuberculosis Lipoarabinomannan into Macrophage Membrane Rafts Is a Prerequisite for the Phagosomal Maturation Block A Welin, ME Winberg, H Abdalla, E Särndahl, B Rasmusson, O Stendahl, ... Infection and immunity 76 (7), 2882-2887, 2008 | 161 | 2008 |
Gene polymorphisms in the NALP3 inflammasome are associated with interleukin‐1 production and severe inflammation: relation to common inflammatory diseases? D Verma, M Lerm, R Blomgran Julinder, P Eriksson, P Söderkvist, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 143 | 2008 |
Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects D Verma, VR Parasa, J Raffetseder, M Martis, RB Mehta, M Netea, ... Scientific reports 7 (1), 12305, 2017 | 134 | 2017 |
Bacterial protein toxins targeting rho GTPases M Lerm, G Schmidt, K Aktories FEMS microbiology letters 188 (1), 1-6, 2000 | 124 | 2000 |
Inside or outside the phagosome? The controversy of the intracellular localization of Mycobacterium tuberculosis A Welin, M Lerm Tuberculosis 92 (2), 113-120, 2012 | 120 | 2012 |
TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation B Zurek, I Schoultz, A Neerincx, LM Napolitano, K Birkner, E Bennek, ... PloS one 7 (7), e41255, 2012 | 119 | 2012 |
Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac M Lerm, M Pop, G Fritz, K Aktories, G Schmidt Infection and immunity 70 (8), 4053-4058, 2002 | 113 | 2002 |
Importance of Phagosomal Functionality for Growth Restriction of Mycobacterium tuberculosis in Primary Human Macrophages A Welin, J Raffetseder, D Eklund, O Stendahl, M Lerm Journal of innate immunity 3 (5), 508-518, 2011 | 110 | 2011 |
Identification of the region of rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1) M Lerm, G Schmidt, UM Goehring, J Schirmer, K Aktories Journal of Biological Chemistry 274 (41), 28999-29004, 1999 | 92 | 1999 |
Identification of the C-terminal Part of BordetellaDermonecrotic Toxin as a Transglutaminase for Rho GTPases G Schmidt, UM Goehring, J Schirmer, M Lerm, K Aktories Journal of Biological Chemistry 274 (45), 31875-31881, 1999 | 91 | 1999 |
Effective delivery of the anti-mycobacterial peptide NZX in mesoporous silica nanoparticles E Tenland, A Pochert, N Krishnan, K Umashankar Rao, S Kalsum, ... PLoS One 14 (2), e0212858, 2019 | 90 | 2019 |
Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue VR Parasa, MJ Rahman, AT Ngyuen Hoang, M Svensson, S Brighenti, ... Disease models & mechanisms 7 (2), 281-288, 2014 | 87 | 2014 |
Leishmania donovani lipophosphoglycan inhibits phagosomal maturation via action on membrane rafts ME Winberg, Å Holm, E Särndahl, AF Vinet, A Descoteaux, ... Microbes and infection 11 (2), 215-222, 2009 | 77 | 2009 |
Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X1-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y1 and P2Y12 receptor activation H Kälvegren, C Skoglund, C Helldahl, M Lerm, M Grenegård, ... Thrombosis and haemostasis 103 (02), 398-407, 2010 | 74 | 2010 |