Articles with public access mandates - Alessia LigrestiLearn more
Not available anywhere: 12
Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: Development, characterization and in vitro evaluation of their antitumoral efficacy
DHP De La Ossa, A Ligresti, ME Gil-Alegre, MR Aberturas, J Molpeceres, ...
Journal of controlled release 161 (3), 927-932, 2012
Mandates: Government of Spain
Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties
AE Ghonim, A Ligresti, A Rabbito, AM Mahmoud, V Di Marzo, NA Osman, ...
European journal of medicinal chemistry 180, 154-170, 2019
Mandates: US National Institutes of Health
Rational Design, Synthesis, and Pharmacological Properties of New 1,8-Naphthyridin-2(1H)-on-3-Carboxamide Derivatives as Highly Selective Cannabinoid-2 …
C Manera, G Saccomanni, B Adinolfi, V Benetti, A Ligresti, MG Cascio, ...
Journal of medicinal chemistry 52 (12), 3644-3651, 2009
Mandates: US National Institutes of Health
Investigations on the 4-quinolone-3-carboxylic acid motif. 7. Synthesis and pharmacological evaluation of 4-quinolone-3-carboxamides and 4-hydroxy-2-quinolone-3-carboxamides as …
C Mugnaini, A Brizzi, A Ligresti, M Allarà, S Lamponi, F Vacondio, C Silva, ...
Journal of medicinal chemistry 59 (3), 1052-1067, 2016
Mandates: Government of Italy
New Resorcinol− Anandamide “Hybrids” as Potent Cannabinoid Receptor Ligands Endowed with Antinociceptive Activity in Vivo
A Brizzi, V Brizzi, MG Cascio, F Corelli, F Guida, A Ligresti, S Maione, ...
Journal of medicinal chemistry 52 (8), 2506-2514, 2009
Mandates: US National Institutes of Health
1, 2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor
V Lucchesi, T Parkkari, JR Savinainen, AM Malfitano, M Allara, S Bertini, ...
European Journal of Medicinal Chemistry 74, 524-532, 2014
Mandates: Government of Italy
Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in …
F Tinto, AS Archambault, É Dumais, V Rakotoarivelo, M Kostrzewa, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2021
Mandates: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty …
F Intranuovo, L Brunetti, P DelRe, GF Mangiatordi, A Stefanachi, ...
Journal of Medicinal Chemistry 66 (1), 235-250, 2022
Mandates: European Molecular Biology Laboratory, European Commission, Government of Spain
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity
A Brizzi, F Aiello, S Boccella, MG Cascio, L De Petrocellis, M Frosini, ...
Bioorganic & Medicinal Chemistry 28 (11), 115513, 2020
Mandates: Government of Italy
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R)
G Graziano, P Delre, F Carofiglio, J Brea, A Ligresti, M Kostrzewa, ...
European Journal of Medicinal Chemistry 248, 115109, 2023
Mandates: European Commission, Government of Spain
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo
C Mugnaini, A Brizzi, M Paolino, E Scarselli, R Castelli, M de Candia, ...
ACS Chemical Neuroscience 15 (5), 955-971, 2024
Mandates: Department of Biotechnology, India
Synthesis of the Major Mammalian Metabolites of THCV
F Tinto, R Villano, M Kostrzewa, A Ligresti, H Straker, E Manzo
Journal of Natural Products 83 (7), 2060-2065, 2020
Mandates: Government of Italy
Available somewhere: 24
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1
K Stock, J Kumar, M Synowitz, S Petrosino, R Imperatore, ESJ Smith, ...
Nature medicine 18 (8), 1232-1238, 2012
Mandates: US National Institutes of Health
Altered endocannabinoid signalling after a high-fat diet in Apoe −/− mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance
A Bartelt, P Orlando, C Mele, A Ligresti, K Toedter, L Scheja, J Heeren, ...
Diabetologia 54, 2900-2910, 2011
Mandates: US National Institutes of Health, German Research Foundation
Fatty acid amide hydrolase (FAAH), acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE): networked targets for the development of carbamates as potential anti …
S Montanari, L Scalvini, M Bartolini, F Belluti, S Gobbi, V Andrisano, ...
Journal of Medicinal Chemistry 59 (13), 6387-6406, 2016
Mandates: Government of Italy
Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure− affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3 …
S Pasquini, A Ligresti, C Mugnaini, T Semeraro, L Cicione, M De Rosa, ...
Journal of medicinal chemistry 53 (16), 5915-5928, 2010
Mandates: US National Institutes of Health
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3 …
V Lucchesi, DP Hurst, DM Shore, S Bertini, BM Ehrmann, M Allarà, ...
Journal of Medicinal Chemistry 57 (21), 8777-8791, 2014
Mandates: US National Institutes of Health, Government of Italy
Cannabinomimetic lipid from a marine cyanobacterium
M Gutiérrez, AR Pereira, HM Debonsi, A Ligresti, V Di Marzo, WH Gerwick
Journal of Natural Products 74 (10), 2313-2317, 2011
Mandates: US National Institutes of Health
New quinolone-and 1, 8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno–modulatory activity
C Manera, AM Malfitano, T Parkkari, V Lucchesi, S Carpi, S Fogli, ...
European Journal of Medicinal Chemistry 97, 10-18, 2015
Mandates: Academy of Finland, Government of Italy
Investigations on the 4‐Quinolone‐3‐Carboxylic Acid Motif Part 5: Modulation of the Physicochemical Profile of a Set of Potent and Selective Cannabinoid‐2 Receptor Ligands …
C Mugnaini, S Nocerino, V Pedani, S Pasquini, A Tafi, M De Chiaro, ...
ChemMedChem 7 (5), 920-934, 2012
Mandates: US National Institutes of Health
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