Synthesis, activity, and structure− activity relationship studies of novel cationic lipids for DNA transfer G Byk, C Dubertret, V Escriou, M Frederic, G Jaslin, R Rangara, B Pitard, ... Journal of medicinal chemistry 41 (2), 224-235, 1998 | 413 | 1998 |
Backbone cyclization: a new method for conferring conformational constraint on peptides C Gilon, D Halle, M Chorev, Z Selincer, G Byk Biopolymers: Original Research on Biomolecules 31 (6), 745-750, 1991 | 286 | 1991 |
Cationic lipid-mediated gene transfer: effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes V Escriou, C Ciolina, F Lacroix, G Byk, D Scherman, P Wils Biochimica et Biophysica Acta (BBA)-Biomembranes 1368 (2), 276-288, 1998 | 251 | 1998 |
Virus-sized self-assembling lamellar complexes between plasmid DNA and cationic micelles promote gene transfer B Pitard, O Aguerre, M Airiau, AM Lachagès, T Boukhnikachvili, G Byk, ... Proceedings of the National Academy of Sciences 94 (26), 14412-14417, 1997 | 195 | 1997 |
Reducible cationic lipids for gene transfer B Wetzer, G Byk, M FREDERIC, M AIRIAU, F BLANCHE, B PITARD, ... Biochemical Journal 356 (3), 747-756, 2001 | 167 | 2001 |
Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin α C Ciolina, G Byk, F Blanche, V Thuillier, D Scherman, P Wils Bioconjugate chemistry 10 (1), 49-55, 1999 | 166 | 1999 |
Reduction-sensitive lipopolyamines as a novel nonviral gene delivery system for modulated release of DNA with improved transgene expression G Byk, B Wetzer, M Frederic, C Dubertret, B Pitard, G Jaslin, D Scherman Journal of medicinal chemistry 43 (23), 4377-4387, 2000 | 150 | 2000 |
Synthetic DNA-compacting peptides derived from human sequence enhance cationic lipid-mediated gene transfer in vitro and in vivo B Schwartz, MA Ivanov, B Pitard, V Escriou, R Rangara, G Byk, P Wils, ... Gene therapy 6 (2), 282-292, 1999 | 142 | 1999 |
Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation C Neves, G Byk, D Scherman, P Wils FEBS letters 453 (1-2), 41-45, 1999 | 113 | 1999 |
Involvement of adenosine in the antiinflammatory action of ketamine J Mazar, B Rogachev, G Shaked, NY Ziv, D Czeiger, C Chaimovitz, ... The Journal of the American Society of Anesthesiologists 102 (6), 1174-1181, 2005 | 110 | 2005 |
Synthesis and biological activity of NK-1 selective, N-backbone cyclic analogs of the C-terminal hexapeptide of substance P G Byk, D Halle, I Zeltser, G Bitan, Z Selinger, C Gilon Journal of medicinal chemistry 39 (16), 3174-3178, 1996 | 80 | 1996 |
New regioselective multicomponent reaction: one pot synthesis of spiro heterobicyclic aliphatic rings G Byk, HE Gottlieb, J Herscovici, F Mirkin Journal of Combinatorial Chemistry 2 (6), 732-735, 2000 | 75 | 2000 |
Intracellular fate and nuclear targeting of plasmid DNA C Neves, V Escriou, G Byk, D Scherman, P Wils Cell biology and toxicology 15, 193-202, 1999 | 70 | 1999 |
Design, synthesis, and evaluation of gadolinium cationic lipids as tools for biodistribution studies of gene delivery complexes F Leclercq, M Cohen-Ohana, N Mignet, A Sbarbati, J Herscovici, ... Bioconjugate chemistry 14 (1), 112-119, 2003 | 62 | 2003 |
One pot synthesis of unsymmetrically functionalized polyamines by a solid phase strategy starting from their symmetrical polyamine-counterparts G Byk, M Frederic, D Scherman Tetrahedron letters 38 (18), 3219-3222, 1997 | 62 | 1997 |
Building units for N-backbone cyclic peptides. 1. Synthesis of protected N-(. omega.-aminoalkylene) amino acids and their incorporation into dipeptide units G Byk, C Gilon The Journal of Organic Chemistry 57 (21), 5687-5692, 1992 | 62 | 1992 |
Synthesis and functionalization of persistent luminescence nanoparticles with small molecules and evaluation of their targeting ability T Maldiney, G Byk, N Wattier, J Seguin, R Khandadash, M Bessodes, ... International journal of pharmaceutics 423 (1), 102-107, 2012 | 53 | 2012 |
Lipopolyamines as transfection agents and pharamaceutical uses thereof G Byk, D Scherman, C Dubertret US Patent 6,107,286, 2000 | 49 | 2000 |
Conformation of cyclic analogs of substance P: NMR and molecular dynamics in dimethyl sulfoxide J Saulitis, DF Mierke, G Byk, C Gilon, H Kessler Journal of the American Chemical Society 114 (12), 4818-4827, 1992 | 49 | 1992 |
Nucleic acid-containing composition, preparation and use thereof D Scherman, G Byk, B Schwartz US Patent 5,945,400, 1999 | 46 | 1999 |