Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach S Gauci, AO Helbig, M Slijper, J Krijgsveld, AJR Heck, S Mohammed Analytical chemistry 81 (11), 4493-4501, 2009 | 340 | 2009 |
Exploring the membrane proteome—challenges and analytical strategies AO Helbig, AJR Heck, M Slijper Journal of proteomics 73 (5), 868-878, 2010 | 163 | 2010 |
Profiling of N-acetylated protein termini provides in-depth insights into the N-terminal nature of the proteome AO Helbig, S Gauci, R Raijmakers, B van Breukelen, M Slijper, ... Molecular & Cellular Proteomics 9 (5), 928-939, 2010 | 150 | 2010 |
Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels AO Helbig, S Rosati, PWWM Pijnappel, B van Breukelen, MHTH Timmers, ... BMC genomics 11, 1-15, 2010 | 104 | 2010 |
Strong cation exchange-based fractionation of Lys-N-generated peptides facilitates the targeted analysis of post-translational modifications N Taouatas, AFM Altelaar, MM Drugan, AO Helbig, S Mohammed, ... Molecular & Cellular Proteomics 8 (1), 190-200, 2009 | 98 | 2009 |
Degradome of soluble ADAM10 and ADAM17 metalloproteases F Scharfenberg, A Helbig, M Sammel, J Benzel, U Schlomann, F Peters, ... Cellular and Molecular Life Sciences 77, 331-350, 2020 | 58 | 2020 |
Novel NEDD1 phosphorylation sites regulate γ-tubulin bindingand mitotic spindle assembly. M Gomez-Ferreria, M Bashkurov, A Helbig, B Larsen, T Pawson, ... Journal of cell science, 2012 | 56 | 2012 |
A three‐way proteomics strategy allows differential analysis of yeast mitochondrial membrane protein complexes under anaerobic and aerobic conditions AO Helbig, MJL de Groot, RA van Gestel, S Mohammed, EAF de Hulster, ... Proteomics 9 (20), 4787-4798, 2009 | 45 | 2009 |
The diversity of protein turnover and abundance under nitrogen-limited steady-state conditions in Saccharomyces cerevisiae AO Helbig, P Daran-Lapujade, AJA van Maris, EAF de Hulster, ... Molecular Biosystems 7 (12), 3316-3326, 2011 | 39 | 2011 |
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis T Mentrup, K Theodorou, F Cabrera-Cabrera, AO Helbig, K Happ, ... Journal of Experimental Medicine 216 (4), 807-830, 2019 | 38 | 2019 |
Multidimensional separation schemes enhance the identification and molecular characterization of low molecular weight proteomes and short open reading frame-encoded peptides in … L Cassidy, AO Helbig, PT Kaulich, K Weidenbach, RA Schmitz, A Tholey Journal of proteomics 230, 103988, 2021 | 35 | 2021 |
SELPHI: correlation-based identification of kinase-associated networks from global phospho-proteomics data sets E Petsalaki, AO Helbig, A Gopal, A Pasculescu, FP Roth, T Pawson Nucleic acids research 43 (W1), W276-W282, 2015 | 30 | 2015 |
A novel septal protein of multicellular heterocystous cyanobacteria is associated with the divisome BL Springstein, S Arévalo, AO Helbig, A Herrero, K Stucken, E Flores, ... Molecular microbiology 113 (6), 1140-1154, 2020 | 25 | 2020 |
Identification and characterization of novel filament-forming proteins in cyanobacteria BL Springstein, C Woehle, J Weissenbach, AO Helbig, T Dagan, ... Scientific reports 10 (1), 1894, 2020 | 25 | 2020 |
The E3 ubiquitin ligase HectD3 attenuates cardiac hypertrophy and inflammation in mice AY Rangrez, A Borlepawar, N Schmiedel, A Deshpande, A Remes, ... Communications biology 3 (1), 562, 2020 | 21 | 2020 |
Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation R Fernandez-Alonso, F Bustos, M Budzyk, P Kumar, AO Helbig, ... Nature communications 11 (1), 1357, 2020 | 17 | 2020 |
Combination of SCX fractionation and charge-reversal derivatization facilitates the identification of nontryptic peptides in C-terminomics P Kaleja, AO Helbig, A Tholey Journal of proteome research 18 (7), 2954-2964, 2019 | 17 | 2019 |
High complexity of Glutamine synthetase regulation in Methanosarcina mazei: Small protein 26 interacts and enhances glutamine synthetase activity M Gutt, B Jordan, K Weidenbach, M Gudzuhn, C Kiessling, L Cassidy, ... The FEBS journal 288 (18), 5350-5373, 2021 | 13 | 2021 |
Two novel heteropolymer‐forming proteins maintain the multicellular shape of the cyanobacterium Anabaena sp. PCC 7120 BL Springstein, DJ Nürnberg, C Woehle, J Weissenbach, ML Theune, ... The FEBS Journal 288 (10), 3197-3216, 2021 | 8 | 2021 |
Exopeptidase assisted N-and C-terminal proteome sequencing AO Helbig, A Tholey Analytical chemistry 92 (7), 5023-5032, 2020 | 6 | 2020 |