An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements K Itoh, T Chiba, S Takahashi, T Ishii, K Igarashi, Y Katoh, T Oyake, ... Biochemical and biophysical research communications 236 (2), 313-322, 1997 | 4468 | 1997 |
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain K Itoh, N Wakabayashi, Y Katoh, T Ishii, K Igarashi, JD Engel, ... Genes & development 13 (1), 76-86, 1999 | 4058 | 1999 |
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2 A Kobayashi, MI Kang, H Okawa, M Ohtsuji, Y Zenke, T Chiba, K Igarashi, ... Molecular and cellular biology 24 (16), 7130-7139, 2004 | 2469 | 2004 |
A third recognition element in bacterial promoters: DNA binding by the α subunit of RNA polymerase W Ross, KK Gosink, J Salomon, K Igarashi, C Zou, A Ishihama, ... Science 262 (5138), 1407-1413, 1993 | 1011 | 1993 |
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene J Sun, H Hoshino, K Takaku, O Nakajima, A Muto, H Suzuki, S Tashiro, ... The EMBO journal, 2002 | 777 | 2002 |
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site T Oyake, K Itoh, H Motohashi, N Hayashi, H Hoshino, M Nishizawa, ... Molecular and cellular biology 16 (11), 6083-6095, 1996 | 747 | 1996 |
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1 K Ogawa, J Sun, S Taketani, O Nakajima, C Nishitani, S Sassa, ... The EMBO journal, 2001 | 651 | 2001 |
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins K Igarashi, K Kataokat, K Itoh, N Hayashi, M Nishizawa, M Yamamoto Nature 367 (6463), 568-572, 1994 | 544 | 1994 |
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins K Itoh, K Igarashi, N Hayashi, M Nishizawa, M Yamamoto Molecular and cellular biology 15 (8), 4184-4193, 1995 | 531 | 1995 |
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics T Ikura, S Tashiro, A Kakino, H Shima, N Jacob, R Amunugama, K Yoder, ... Molecular and cellular biology, 2007 | 446 | 2007 |
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages M Haldar, M Kohyama, AYL So, KC Wumesh, X Wu, CG Briseño, ... Cell 156 (6), 1223-1234, 2014 | 441 | 2014 |
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ... Nature 498 (7455), 506-510, 2013 | 436 | 2013 |
Bipartite functional map of the E. coli RNA polymerase α subunit: involvement of the C-terminal region in transcription activation by cAMP-CRP K Igarashi, A Ishihama Cell 65 (6), 1015-1022, 1991 | 427 | 1991 |
Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network J Sun, M Brand, Y Zenke, S Tashiro, M Groudine, K Igarashi Proceedings of the National Academy of Sciences 101 (6), 1461-1466, 2004 | 426 | 2004 |
Molecular cloning and functional characterization of a new Cap'n'collar family transcription factor Nrf3 A Kobayashi, E Ito, T Toki, K Kogame, S Takahashi, K Igarashi, N Hayashi, ... Journal of Biological Chemistry 274 (10), 6443-6452, 1999 | 370 | 1999 |
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway … AK MacLeod, M McMahon, SM Plummer, LG Higgins, TM Penning, ... Carcinogenesis 30 (9), 1571-1580, 2009 | 363 | 2009 |
The transcriptional programme of antibody class switching involves the repressor Bach2 A Muto, S Tashiro, O Nakajima, H Hoshino, S Takahashi, E Sakoda, ... Nature 429 (6991), 566-571, 2004 | 351 | 2004 |
The world according to Maf H Motohashi, JA Shavit, K Igarashi, M Yamamoto, JD Engel Nucleic acids research 25 (15), 2953-2959, 1997 | 340 | 1997 |
The superoxide‐producing NAD (P) H oxidase Nox4 in the nucleus of human vascular endothelial cells J Kuroda, K Nakagawa, T Yamasaki, K Nakamura, R Takeya, ... Genes to Cells 10 (12), 1139-1151, 2005 | 339 | 2005 |
Heme induces ubiquitination and degradation of the transcription factor Bach1 Y Zenke-Kawasaki, Y Dohi, Y Katoh, T Ikura, M Ikura, T Asahara, ... Molecular and cellular biology, 2007 | 338 | 2007 |