Stress as risk factor for Alzheimer’s disease A Caruso, F Nicoletti, D Mango, A Saidi, R Orlando, S Scaccianoce Pharmacological research 132, 130-134, 2018 | 104 | 2018 |
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system L Di Menna, ME Joffe, L Iacovelli, R Orlando, CW Lindsley, J Mairesse, ... Neuropharmacology 128, 301-313, 2018 | 93 | 2018 |
Nanomolar concentrations of anabolic–androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures R Orlando, A Caruso, G Molinaro, M Motolese, F Matrisciano, G Togna, ... Brain research 1165, 21-29, 2007 | 83 | 2007 |
Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage F Matrisciano, CL Busceti, D Bucci, R Orlando, A Caruso, G Molinaro, ... PLoS one 6 (1), e16447, 2011 | 74 | 2011 |
Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats F Matrisciano, A Caruso, R Orlando, M Marchiafava, V Bruno, G Battaglia, ... Neuropharmacology 55 (4), 525-531, 2008 | 61 | 2008 |
Molecular pharmacodynamics of new oral drugs used in the treatment of multiple sclerosis L di Nuzzo, R Orlando, C Nasca, F Nicoletti Drug design, development and therapy, 555-568, 2014 | 55 | 2014 |
Antidepressant activity of fingolimod in mice L di Nuzzo, R Orlando, C Tognoli, P Di Pietro, G Bertini, J Miele, D Bucci, ... Pharmacology Research & Perspectives 3 (3), e00135, 2015 | 50 | 2015 |
Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia F Nicoletti, R Orlando, L Di Menna, M Cannella, S Notartomaso, G Mascio, ... Frontiers in psychiatry 10, 49, 2019 | 39 | 2019 |
Cigarette smoke inhibits adenine nucleotide hydrolysis by human platelets AR Togna, V Latina, R Orlando, GI Togna Platelets 19 (7), 537-542, 2008 | 35 | 2008 |
Exposure to predator odor and resulting anxiety enhances the expression of the α2δ subunit of voltage‐sensitive calcium channels in the amygdala C Nasca, R Orlando, M Marchiafava, P Boldrini, G Battaglia, ... Journal of neurochemistry 125 (5), 649-656, 2013 | 22 | 2013 |
mGlu3 receptor regulates microglial cell reactivity in neonatal rats M Zinni, J Mairesse, J Pansiot, F Fazio, L Iacovelli, N Antenucci, ... Journal of Neuroinflammation 18, 1-16, 2021 | 17 | 2021 |
GPCR interactions involving metabotropic glutamate receptors and their relevance to the pathophysiology and treatment of CNS disorders F Nicoletti, L Di Menna, L Iacovelli, R Orlando, AR Zuena, PJ Conn, ... Neuropharmacology 235, 109569, 2023 | 12 | 2023 |
In Vivo Non-radioactive Assessment of mGlu5 Receptor-Activated Polyphosphoinositide Hydrolysis in Response to Systemic Administration of a Positive Allosteric … AR Zuena, L Iacovelli, R Orlando, L Di Menna, P Casolini, GS Alema, ... Frontiers in pharmacology 9, 804, 2018 | 12 | 2018 |
Targeting mGlu5 metabotropic glutamate receptors in the treatment of cognitive dysfunction in a mouse model of phenylketonuria F Nardecchia, R Orlando, L Iacovelli, M Colamartino, E Fiori, V Leuzzi, ... Frontiers in Neuroscience 12, 154, 2018 | 12 | 2018 |
Gender differences in the use of cardiovascular interventions in HIV‐positive persons; the D: A: D Study CI Hatleberg, L Ryom, W El‐Sadr, A Mocroft, P Reiss, S De Wit, F Dabis, ... African Journal of Reproduction and Gynaecological Endoscopy 21 (3), 2018 | 12 | 2018 |
Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 … R Orlando, M Borro, M Motolese, G Molinaro, S Scaccianoce, A Caruso, ... Neuropharmacology 86, 133-144, 2014 | 12 | 2014 |
Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus I Panaccione, L Iacovelli, L di Nuzzo, F Nardecchia, G Mauro, D Janiri, ... Pharmacological Research 117, 46-53, 2017 | 8 | 2017 |
Targeting metabotropic glutamate receptors in the treatment of primary brain tumors L Iacovelli, R Orlando, A Rossi, P Spinsanti, D Melchiorri, F Nicoletti Current Opinion in Pharmacology 38, 59-64, 2018 | 5 | 2018 |
Changes in mGlu5 receptor signaling are associated with associative learning and memory extinction in mice AE Teleuca, GS Alemà, P Casolini, I Barberis, F Ciabattoni, R Orlando, ... Life 12 (3), 463, 2022 | 4 | 2022 |
Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling L Iacovelli, L Di Menna, D Peterlik, C Stangl, R Orlando, G Molinaro, ... Neuropharmacology 113, 343-353, 2017 | 4 | 2017 |