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Seychelle Vos
Seychelle Vos
Assistant Professor, MIT Department of Biology
Verified email at mit.edu - Homepage
Title
Cited by
Cited by
Year
All tangled up: how cells direct, manage and exploit topoisomerase function
SM Vos, EM Tretter, BH Schmidt, JM Berger
Nature reviews Molecular cell biology 12 (12), 827-841, 2011
7032011
Structure of activated transcription complex Pol II–DSIF–PAF–SPT6
SM Vos, L Farnung, M Boehning, C Wigge, A Linden, H Urlaub, P Cramer
Nature 560 (7720), 607-612, 2018
3892018
Structure of paused transcription complex Pol II–DSIF–NELF
SM Vos, L Farnung, H Urlaub, P Cramer
Nature 560 (7720), 601-606, 2018
3492018
Nucleosome–Chd1 structure and implications for chromatin remodelling
L Farnung, SM Vos, C Wigge, P Cramer
Nature 550 (7677), 539-542, 2017
2482017
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation
SM Vos, L Farnung, A Linden, H Urlaub, P Cramer
Nature Structural & Molecular Biology 27 (7), 668-677, 2020
1262020
MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation
A Baluapuri, J Hofstetter, ND Stankovic, T Endres, P Bhandare, SM Vos, ...
Molecular cell 74 (4), 674-687. e11, 2019
1262019
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction
Y Li, NK Stewart, AJ Berger, S Vos, AJ Schoeffler, JM Berger, BT Chait, ...
Proceedings of the National Academy of Sciences 107 (44), 18832-18837, 2010
1212010
Structure of transcribing RNA polymerase II-nucleosome complex
L Farnung, SM Vos, P Cramer
Nature communications 9 (1), 5432, 2018
1052018
Stress-induced nuclear condensation of NELF drives transcriptional downregulation
P Rawat, M Boehning, B Hummel, F Aprile-Garcia, AS Pandit, ...
Molecular cell 81 (5), 1013-1026. e11, 2021
992021
Structure of a transcribing RNA polymerase II–U1 snRNP complex
S Zhang, S Aibara, SM Vos, DE Agafonov, R Lührmann, P Cramer
Science 371 (6526), 305-309, 2021
972021
Architecture and RNA binding of the human negative elongation factor
SM Vos, D Pöllmann, L Caizzi, KB Hofmann, P Rombaut, T Zimniak, ...
Elife 5, e14981, 2016
782016
RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases
S Battaglia, M Lidschreiber, C Baejen, P Torkler, SM Vos, P Cramer
Elife 6, e25637, 2017
632017
Structural basis of nucleosome retention during transcription elongation
M Filipovski, JHM Soffers, SM Vos, L Farnung
Science 376 (6599), 1313-1316, 2022
552022
Structure of a backtracked hexasomal intermediate of nucleosome transcription
L Farnung, M Ochmann, G Garg, SM Vos, P Cramer
Molecular Cell 82 (17), 3126-3134. e7, 2022
442022
Drugging the “undruggable” MYCN oncogenic transcription factor: overcoming previous obstacles to impact childhood cancers
AJ Wolpaw, R Bayliss, G Büchel, CV Dang, M Eilers, WC Gustafson, ...
Cancer research 81 (7), 1627-1632, 2021
422021
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters
T Endres, D Solvie, JB Heidelberger, V Andrioletti, A Baluapuri, CP Ade, ...
Molecular cell 81 (4), 830-844. e13, 2021
372021
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
D Papadopoulos, D Solvie, A Baluapuri, T Endres, SA Ha, S Herold, ...
Molecular cell 82 (1), 159-176. e12, 2022
352022
Structural basis for the MukB‐topoisomerase IV interaction and its functional implications in vivo
SM Vos, NK Stewart, MG Oakley, JM Berger
The EMBO journal 32 (22), 2950-2962, 2013
332013
Assembly of RNA polymerase II transcription initiation complexes
L Farnung, SM Vos
Current opinion in structural biology 73, 102335, 2022
282022
Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein
SM Vos, AY Lyubimov, DM Hershey, AJ Schoeffler, S Sengupta, ...
Genes & development 28 (13), 1485-1497, 2014
232014
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