| Plants as sources of natural and recombinant anti-cancer agents JF Buyel Biotechnology advances 36 (2), 506-520, 2018 | 222 | 2018 |
| Very-large-scale production of antibodies in plants: The biologization of manufacturing JF Buyel, RM Twyman, R Fischer Biotechnology advances 35 (4), 458-465, 2017 | 189 | 2017 |
| Molecular farming–the slope of enlightenment R Fischer, JF Buyel Biotechnology advances 40, 107519, 2020 | 185 | 2020 |
| Extraction and downstream processing of plant-derived recombinant proteins JF Buyel, RM Twyman, R Fischer Biotechnology Advances 33 (6), 902-913, 2015 | 154 | 2015 |
| Commercial aspects of pharmaceutical protein production in plants R Fischer, S Schillberg, J F Buyel, R M Twyman Current pharmaceutical design 19 (31), 5471-5477, 2013 | 150 | 2013 |
| Predictive models for transient protein expression in tobacco (Nicotiana tabacum L.) can optimize process time, yield, and downstream costs JF Buyel, R Fischer Biotechnology and bioengineering 109 (10), 2575-2588, 2012 | 144 | 2012 |
| Plant molecular farming–integration and exploitation of side streams to achieve sustainable biomanufacturing JF Buyel Frontiers in plant science 9, 1893, 2019 | 139 | 2019 |
| Scale‐down models to optimize a filter train for the downstream purification of recombinant pharmaceutical proteins produced in tobacco leaves JF Buyel, R Fischer Biotechnology journal 9 (3), 415-425, 2014 | 73 | 2014 |
| The emergency response capacity of plant-based biopharmaceutical manufacturing-what it is and what it could be D Tusé, S Nandi, KA McDonald, JF Buyel Frontiers in Plant Science 11, 594019, 2020 | 72 | 2020 |
| On the verge of the market–plant factories for the automated and standardized production of biopharmaceuticals JW Huebbers, JF Buyel Biotechnology Advances 46, 107681, 2021 | 67 | 2021 |
| Flocculation increases the efficacy of depth filtration during the downstream processing of recombinant pharmaceutical proteins produced in tobacco JF Buyel, R Fischer Plant biotechnology journal 12 (2), 240-252, 2014 | 66 | 2014 |
| Plant cell packs: a scalable platform for recombinant protein production and metabolic engineering T Rademacher, M Sack, D Blessing, R Fischer, T Holland, J Buyel Plant biotechnology journal 17 (8), 1560-1566, 2019 | 63 | 2019 |
| Rational design of a host cell protein heat precipitation step simplifies the subsequent purification of recombinant proteins from tobacco JF Buyel, HM Gruchow, A Boes, R Fischer Biochemical Engineering Journal 88, 162-170, 2014 | 63 | 2014 |
| Downstream processing of biopharmaceutical proteins produced in plants: the pros and cons of flocculants JF Buyel, R Fischer Bioengineered 5 (2), 138-142, 2014 | 55 | 2014 |
| Optimized blanching reduces the host cell protein content and substantially enhances the recovery and stability of two plant-derived malaria vaccine candidates S Menzel, T Holland, A Boes, H Spiegel, J Bolzenius, R Fischer, JF Buyel Frontiers in plant science 7, 159, 2016 | 52 | 2016 |
| Process Development Strategies in Plant Molecular Farming J F Buyel Current pharmaceutical biotechnology 16 (11), 966-982, 2015 | 52 | 2015 |
| The use of quantitative structure–activity relationship models to develop optimized processes for the removal of tobacco host cell proteins during biopharmaceutical production JF Buyel, JA Woo, SM Cramer, R Fischer Journal of Chromatography A 1322, 18-28, 2013 | 52 | 2013 |
| Comparison of microbial and transient expression (tobacco plants and plant‐cell packs) for the production and purification of the anticancer mistletoe lectin viscumin BB Gengenbach, LL Keil, P Opdensteinen, CR Müschen, G Melmer, ... Biotechnology and bioengineering 116 (9), 2236-2249, 2019 | 50 | 2019 |
| Contributions of the international plant science community to the fight against human infectious diseases–part 1: epidemic and pandemic diseases M Lobato Gomez, X Huang, D Alvarez, W He, C Baysal, C Zhu, ... Plant biotechnology journal 19 (10), 1901-1920, 2021 | 49 | 2021 |
| Current status and perspectives of the molecular farming landscape H Spiegel, E Stöger, RM Twyman, JF Buyel Molecular pharming: Applications, challenges, and emerging areas, 1-23, 2018 | 47 | 2018 |
Rainer FischerProfessor for Molecular BiotechnologyVerified email at ime.fraunhofer.de