Articles with public access mandates - Caroline HeckmanLearn more
Not available anywhere: 8
Review
Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia
JL Kivioja, A Thanasopoulou, A Kumar, M Kontro, B Yadav, MM Majumder, ...
Leukemia 33 (6), 1360-1372, 2019
Mandates: Finnish Funding Agency for Innovation, Swiss Cancer League
Review
Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting
H Karvonen, R Perttilä, W Niininen, V Hautanen, H Barker, A Murumägi, ...
Oncogene 38 (17), 3288-3300, 2019
Mandates: Academy of Finland
Review
Germline alterations in a consecutive series of acute myeloid leukemia
U Wartiovaara-Kautto, EAM Hirvonen, E Pitkänen, C Heckman, J Saarela, ...
Leukemia 32 (10), 2282-2285, 2018
Mandates: Academy of Finland, Finnish Funding Agency for Innovation
Review
Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML
R Karjalainen, M Liu, A Kumar, L He, D Malani, A Parsons, M Kontro, ...
Leukemia 33 (10), 2548-2553, 2019
Mandates: Academy of Finland, Finnish Funding Agency for Innovation
Review
Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition
M Tambe, E Karjalainen, M Vähä-Koskela, D Bulanova, BT Gjertsen, ...
Leukemia 34 (12), 3186-3196, 2020
Mandates: Academy of Finland
Review
Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia
PN Ojamies, M Kontro, H Edgren, P Ellonen, S Lagström, H Almusa, ...
Leukemia 31 (5), 1048-1058, 2017
Mandates: Academy of Finland, Finnish Funding Agency for Innovation, Government of Spain
Review
Statistical detection of quantitative protein biomarkers provides insights into signaling networks deregulated in acute myeloid leukemia
LL Elo, R Karjalainen, T Öhman, P Hintsanen, TA Nyman, CA Heckman, ...
Proteomics 14 (21-22), 2443-2453, 2014
Mandates: Academy of Finland
Review
Case studies investigating genetic heterogeneity between anatomically distinct bone marrow compartments in acute myeloid leukemia
PN Ojamies, M Kontro, H Edgren, P Ellonen, C Heckman, K Porkka, ...
Leukemia & lymphoma 59 (12), 3002-3005, 2018
Mandates: Academy of Finland, Finnish Funding Agency for Innovation
Available somewhere: 79
Review
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ...
New England journal of medicine 366 (20), 1905-1913, 2012
Mandates: US National Institutes of Health
Review
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ...
Blood, The Journal of the American Society of Hematology 121 (22), 4541-4550, 2013
Mandates: US National Institutes of Health
Review
Immunogenomic landscape of hematological malignancies
O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ...
Cancer Cell 38 (3), 380-399. e13, 2020
Mandates: Academy of Finland
Review
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ...
Haematologica 105 (3), 708, 2020
Mandates: Academy of Finland, Finnish Funding Agency for Innovation, European Commission
Review
Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer
A Malyutina, MM Majumder, W Wang, A Pessia, CA Heckman, J Tang
PLoS computational biology 15 (5), e1006752, 2019
Mandates: Academy of Finland, European Commission
Review
MCL-1 inhibitors, fast-lane development of a new class of anti-cancer agents
A Bolomsky, M Vogler, MC Köse, CA Heckman, G Ehx, H Ludwig, J Caers
Journal of hematology & oncology 13, 1-19, 2020
Mandates: National Fund for Scientific Research, Belgium
Review
JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
R Karjalainen, T Pemovska, M Popa, M Liu, KK Javarappa, MM Majumder, ...
Blood, The Journal of the American Society of Hematology 130 (6), 789-802, 2017
Mandates: Academy of Finland, Finnish Funding Agency for Innovation, European …
Review
Implementing a functional precision medicine tumor board for acute myeloid leukemia
D Malani, A Kumar, O Brück, M Kontro, B Yadav, M Hellesøy, ...
Cancer discovery 12 (2), 388-401, 2022
Mandates: Academy of Finland, Finnish Funding Agency for Innovation, Knut and Alice …
Review
Comprehensive drug testing of patient-derived conditionally reprogrammed cells from castration-resistant prostate cancer
K Saeed, V Rahkama, S Eldfors, D Bychkov, JP Mpindi, B Yadav, ...
European urology 71 (3), 319-327, 2017
Mandates: Academy of Finland, Finnish Funding Agency for Innovation
Review
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
M Kontro, A Kumar, MM Majumder, S Eldfors, A Parsons, T Pemovska, ...
Leukemia 31 (2), 301-309, 2017
Mandates: Finnish Funding Agency for Innovation
Review
Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia
E Andersson, H Kuusanmäki, S Bortoluzzi, S Lagström, A Parsons, ...
Leukemia 30 (5), 1204-1208, 2016
Mandates: US National Institutes of Health, Academy of Finland
Review
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation
EI Andersson, HLM Rajala, S Eldfors, P Ellonen, T Olson, A Jerez, ...
Blood cancer journal 3 (12), e168-e168, 2013
Mandates: US National Institutes of Health
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