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Keehoon Jung
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Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution
RP Kataru, K Jung, C Jang, H Yang, RA Schwendener, JE Baik, SH Han, ...
Blood 113 (22), 5650-5659, 2009
4432009
Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy
J Incio, H Liu, P Suboj, SM Chin, IX Chen, M Pinter, MR Ng, HT Nia, ...
Cancer discovery, CD-15-1177, 2016
3862016
Solid stress and elastic energy as measures of tumor mechanopathology
H Nia, H Liu, G Seano, M Datta, D Jones, N Rahbari, J Incio, V Chauhan, ...
Cancer Research 77 (13 Supplement), 3987-3987, 2017
3842017
Solid stress and elastic energy as measures of tumour mechanopathology
HT Nia, H Liu, G Seano, M Datta, D Jones, N Rahbari, J Incio, ...
Nature biomedical engineering 1 (1), 0004, 2017
3812017
Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival
J Kloepper, L Riedemann, Z Amoozgar, G Seano, K Susek, V Yu, ...
Proceedings of the National Academy of Sciences, 201525360, 2016
3362016
Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages
TE Peterson, ND Kirkpatrick, Y Huang, CT Farrar, KA Marijt, J Kloepper, ...
Proceedings of the National Academy of Sciences 113 (16), 4470-4475, 2016
3062016
Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases
NN Rahbari, D Kedrin, J Incio, H Liu, WW Ho, HT Nia, CM Edrich, K Jung, ...
Science translational medicine 8 (360), 360ra135-360ra135, 2016
2262016
Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts
K Jung, P Kim, F Leuschner, R Gorbatov, JK Kim, T Ueno, M Nahrendorf, ...
Circulation research, CIRCRESAHA. 112.300484, 2013
2122013
The lymph node microenvironment and its role in the progression of metastatic cancer
ER Pereira, D Jones, K Jung, TP Padera
Seminars in cell & developmental biology 38, 98-105, 2015
2072015
Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
J Incio, JA Ligibel, DT McManus, P Suboj, K Jung, K Kawaguchi, M Pinter, ...
Science translational medicine 10 (432), eaag0945, 2018
1892018
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage
YJ Koh, HZ Kim, SI Hwang, JE Lee, N Oh, K Jung, M Kim, KE Kim, H Kim, ...
Cancer cell 18 (2), 171-184, 2010
1812010
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy
K Jung, T Heishi, OF Khan, PS Kowalski, J Incio, NN Rahbari, E Chung, ...
The Journal of clinical investigation 127 (8), 3039-3051, 2017
1572017
Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer
BH Jeon, C Jang, J Han, RP Kataru, L Piao, K Jung, HJ Cha, ...
Cancer Research 68 (4), 1100-1109, 2008
1512008
PlGF/VEGFR-1 signaling promotes macrophage polarization and accelerated tumor progression in obesity
J Incio, J Tam, NN Rahbari, P Suboj, DT McManus, SM Chin, TD Vardam, ...
Clinical Cancer Research, 2016
1412016
Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer
K Jung, T Heishi, J Incio, Y Huang, EY Beech, M Pinter, WW Ho, ...
Proceedings of the National Academy of Sciences, 201710754, 2017
1182017
Fabrication and operation of GRIN probes for in vivo fluorescence cellular imaging of internal organs in small animals
JK Kim, WM Lee, P Kim, M Choi, K Jung, S Kim, SH Yun
Nature protocols 7 (8), 1456, 2012
1082012
Double anti-angiogenic and anti-inflammatory protein, Valpha, targeting VEGF-a and TNF-α in retinopathy and psoriasis
K Jung, D Lee, HS Lim, SI Lee, YJ Kim, GM Lee, SC Kim, GY Koh
Journal of Biological Chemistry, jbc. M111. 228130, 2011
582011
Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction
D Jones, EFJ Meijer, C Blatter, S Liao, ER Pereira, EM Bouta, K Jung, ...
Science translational medicine 10 (424), eaam7964, 2018
562018
Fusion proteins binding to vegf and angiopoietin
HZ Kim, YJ Koh, HM Kim, K Jung, C Jeon, GY Koh
US Patent App. 11/932,021, 2008
42*2008
A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis
HZ Kim, K Jung, HM Kim, Y Cheng, GY Koh
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (5), 772-780, 2009
352009
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