Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013 | 10052 | 2013 |
Comprehensive and integrative genomic characterization of hepatocellular carcinoma A Ally, M Balasundaram, R Carlsen, E Chuah, A Clarke, N Dhalla, RA Holt, ... Cell 169 (7), 1327-1341. e23, 2017 | 1847 | 2017 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1796* | 2020 |
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming Y Mitsuishi, K Taguchi, Y Kawatani, T Shibata, T Nukiwa, H Aburatani, ... Cancer cell 22 (1), 66-79, 2012 | 1382 | 2012 |
Genomic spectra of biliary tract cancer H Nakamura, Y Arai, Y Totoki, T Shirota, A Elzawahry, M Kato, N Hama, ... Nature genetics 47 (9), 1003-1010, 2015 | 1155 | 2015 |
Mutational signatures associated with tobacco smoking in human cancer LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ... Science 354 (6312), 618-622, 2016 | 1067 | 2016 |
KIF5B-RET fusions in lung adenocarcinoma T Kohno, H Ichikawa, Y Totoki, K Yasuda, M Hiramoto, T Nammo, ... Nature medicine 18 (3), 375-377, 2012 | 1003 | 2012 |
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators A Fujimoto, Y Totoki, T Abe, KA Boroevich, F Hosoda, HH Nguyen, M Aoki, ... Nature genetics 44 (7), 760-764, 2012 | 967 | 2012 |
Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer S Yachida, S Mizutani, H Shiroma, S Shiba, T Nakajima, T Sakamoto, ... Nature medicine 25 (6), 968-976, 2019 | 966 | 2019 |
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani, A Milanese, JS Fleck, ... Nature medicine 25 (4), 679-689, 2019 | 919 | 2019 |
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non–small-cell lung cancer T Takano, Y Ohe, H Sakamoto, K Tsuta, Y Matsuno, U Tateishi, ... Journal of clinical oncology 23 (28), 6829-6837, 2005 | 879 | 2005 |
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy T Shibata, T Ohta, KI Tong, A Kokubu, R Odogawa, K Tsuta, H Asamura, ... Proceedings of the National Academy of Sciences 105 (36), 13568-13573, 2008 | 851 | 2008 |
Integrated molecular analysis of adult T cell leukemia/lymphoma K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi, T Shimamura, J Yasunaga, ... Nature genetics 47 (11), 1304-1315, 2015 | 816 | 2015 |
Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas H Okayama, T Kohno, Y Ishii, Y Shimada, K Shiraishi, R Iwakawa, ... Cancer research 72 (1), 100-111, 2012 | 799 | 2012 |
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes Y Totoki, K Tatsuno, KR Covington, H Ueda, CJ Creighton, M Kato, S Tsuji, ... Nature genetics 46 (12), 1267-1273, 2014 | 789 | 2014 |
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer discovery 7 (10), 1116-1135, 2017 | 761 | 2017 |
Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth T Ohta, K Iijima, M Miyamoto, I Nakahara, H Tanaka, M Ohtsuji, T Suzuki, ... Cancer research 68 (5), 1303-1309, 2008 | 722 | 2008 |
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation AM Thomas, P Manghi, F Asnicar, E Pasolli, F Armanini, M Zolfo, ... Nature medicine 25 (4), 667-678, 2019 | 713 | 2019 |
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer A Fujimoto, M Furuta, Y Totoki, T Tsunoda, M Kato, Y Shiraishi, H Tanaka, ... Nature genetics 48 (5), 500-509, 2016 | 700 | 2016 |
Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers K Kataoka, Y Shiraishi, Y Takeda, S Sakata, M Matsumoto, S Nagano, ... Nature 534 (7607), 402-406, 2016 | 670 | 2016 |