Articles with public access mandates - Bin ChenLearn more
Not available anywhere: 2
scRNA-Seq and imaging mass cytometry analyses unveil iNKT cells-mediated anti-tumor immunity in pancreatic cancer liver metastasis
Q Yi, J Wang, T Liu, Y Yao, I Loveless, K Subedi, J Toor, I Adrianto, H Xiao, ...
Cancer letters 561, 216149, 2023
Mandates: US National Institutes of Health
Fighting disease with data
M Sirota, B Chen
XRDS: Crossroads, The ACM Magazine for Students 21 (4), 28-33, 2015
Mandates: US National Institutes of Health
Available somewhere: 59
A survey of current trends in computational drug repositioning
J Li, S Zheng, B Chen, AJ Butte, SJ Swamidass, Z Lu
Briefings in bioinformatics 17 (1), 2-12, 2016
Mandates: US National Institutes of Health, National Natural Science Foundation of China
Assessing Drug Target Association using Semantic Linked Data
B Chen, Y Ding, DJ Wild
PLoS Computational Biology 8 (7), e1002574, 2012
Mandates: US National Institutes of Health
Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets
B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte
Nature communications 8 (1), 16022, 2017
Mandates: US National Institutes of Health
Leveraging big data to transform target selection and drug discovery
B Chen, AJ Butte
Clinical Pharmacology & Therapeutics 99 (3), 285-297, 2016
Mandates: US National Institutes of Health
The ChEMBL database as linked open data
EL Willighagen, A Waagmeester, O Spjuth, P Ansell, AJ Williams, ...
Journal of cheminformatics 5 (1), 1-12, 2013
Mandates: Swedish Research Council
Predicting drug target interactions using meta-path-based semantic network analysis
G Fu, Y Ding, A Seal, B Chen, Y Sun, E Bolton
BMC bioinformatics 17 (1), 1-10, 2016
Mandates: US National Institutes of Health
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types
K Yu, B Chen, D Aran, J Charalel, C Yau, DM Wolf, LJ Van ‘T Veer, ...
Nature communications 10 (1), 3574, 2019
Mandates: US National Institutes of Health
Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma
B Chen, L Garmire, DF Calvisi, MS Chua, RK Kelley, X Chen
Nature Reviews Gastroenterology & Hepatology 17 (4), 238-251, 2020
Mandates: US National Institutes of Health
Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data
K Liu, PA Newbury, BS Glicksberg, WZD Zeng, S Paithankar, ...
Nature communications 10 (1), 2138, 2019
Mandates: US National Institutes of Health
A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS
M McMahon, A Contreras, M Holm, T Uechi, CM Forester, X Pang, ...
Elife 8, e48847, 2019
Mandates: US National Institutes of Health
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice
S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ...
Journal of hepatology 67 (6), 1194-1203, 2017
Mandates: US National Institutes of Health, National Natural Science Foundation of …
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell …
B Chen, W Wei, L Ma, B Yang, RM Gill, MS Chua, AJ Butte, S So
Gastroenterology 152 (8), 2022-2036, 2017
Mandates: US National Institutes of Health
Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research
B Chen, M Sirota, H Fan-Minogue, D Hadley, AJ Butte
BMC medical genomics 8 (2), 1-10, 2015
Mandates: Hewlett Foundation, US National Institutes of Health
MoCL: Data-driven Molecular Fingerprint via Knowledge-aware Contrastive Learning from Molecular Graph
M Sun, J Xing, H Wang, B Chen, J Zhou
Proceedings of the 27th ACM SIGKDD Conference on Knowledge Discovery & Data …, 2021
Mandates: US National Science Foundation, US Department of Defense, US National …
Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease
A Taubes, P Nova, KA Zalocusky, I Kosti, M Bicak, MY Zilberter, Y Hao, ...
Nature Aging 1 (10), 932-947, 2021
Mandates: US National Institutes of Health
Characteristics of drug combination therapy in oncology by analyzing clinical trial data on ClinicalTrials. gov
M Wu, M Sirota, AJ Butte, BIN Chen
Pacific Symposium on Biocomputing Co-Chairs, 68-79, 2014
Mandates: US National Institutes of Health
Relating chemical structure to cellular response: an integrative analysis of gene expression, bioactivity, and structural data across 11,000 compounds
B Chen, P Greenside, H Paik, M Sirota, D Hadley, AJ Butte
CPT: pharmacometrics & systems pharmacology 4 (10), 576-584, 2015
Mandates: Hewlett Foundation, US National Institutes of Health
MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities
J Rohrberg, D Van de Mark, M Amouzgar, JV Lee, M Taileb, A Corella, ...
Cell Reports 30 (10), 3368-3382. e7, 2020
Mandates: US National Science Foundation, US Department of Defense, US National …
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