A single step purification, immobilization, and hyperactivation of lipases via interfacial adsorption on strongly hydrophobic supports A Bastida, P Sabuquillo, P Armisen, R Fernández‐Lafuente, J Huguet, ... Biotechnology and bioengineering 58 (5), 486-493, 1998 | 648 | 1998 |
Preparation of activated supports containing low pK amino groups. A new tool for protein immobilization via the carboxyl coupling method R Fernandez-Lafuente, CM Rosell, V Rodríguez, C Santana, G Soler, ... Enzyme and Microbial Technology 15 (7), 546-550, 1993 | 317 | 1993 |
Immobilization‐stabilization of α‐chymotrypsin by covalent attachment to aldehyde‐agarose gels JM Guisán, A Bastida, C Cuesta, R Fernandez‐Lufuente, CM Rosell Biotechnology and Bioengineering 38 (10), 1144-1152, 1991 | 141 | 1991 |
Modulation of lipase properties in macro-aqueous systems by controlled enzyme immobilization: enantioselective hydrolysis of a chiral ester by immobilized Pseudomonas lipase G Fernández-Lorente, M Terreni, C Mateo, A Bastida, ... Enzyme and microbial technology 28 (4-5), 389-396, 2001 | 114 | 2001 |
Overcoming aminoglycoside enzymatic resistance: design of novel antibiotics and inhibitors SG Zárate, MLDC Claure, R Benito-Arenas, J Revuelta, AG Santana, ... Molecules 23 (2), 284, 2018 | 106 | 2018 |
Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance A Bastida, A Hidalgo, JL Chiara, M Torrado, F Corzana, ... Journal of the American Chemical Society 128 (1), 100-116, 2006 | 103 | 2006 |
Enzymes in the synthesis of bioactive compounds: the prodigious decades E Garcı́a-Junceda, JF Garcı́a-Garcı́a, A Bastida, A Fernández-Mayoralas Bioorganic & medicinal chemistry 12 (8), 1817-1834, 2004 | 95 | 2004 |
Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s disease A Samadi, M Chioua, I Bolea, C De Los Ríos, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 46 (9), 4665-4668, 2011 | 85 | 2011 |
Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: implications for drug design T Vacas, F Corzana, G Jimenez-Oses, C Gonzalez, AM Gomez, A Bastida, ... Journal of the American Chemical Society 132 (34), 12074-12090, 2010 | 73 | 2010 |
Immobilization of enzymes acting on macromolecular substrates: reduction of steric problems JM Guisán, G Penzol, P Armisen, A Bastida, RM Blanco, ... Immobilization of enzymes and cells, 261-275, 1997 | 73 | 1997 |
Biocatalyst engineering exerts a dramatic effect on selectivity of hydrolysis catalyzed by immobilized lipases in aqueous medium G Fernandez-Lorente, R Fernández-Lafuente, JM Palomo, C Mateo, ... Journal of Molecular Catalysis B: Enzymatic 11 (4-6), 649-656, 2001 | 71 | 2001 |
Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new … A Samadi, C Valderas, C De Los Ríos, A Bastida, M Chioua, ... Bioorganic & medicinal chemistry 19 (1), 122-133, 2011 | 65 | 2011 |
A thorough experimental study of CH/π interactions in water: quantitative structure–stability relationships for carbohydrate/aromatic complexes E Jiménez-Moreno, G Jiménez-Osés, AM Gómez, AG Santana, F Corzana, ... Chemical Science 6 (11), 6076-6085, 2015 | 63 | 2015 |
Effect of immiscible organic solvents on activity/stability of native chymotrypsin and immobilized‐stabilized derivatives RM Blanco, PJ Halling, A Bastida, C Cuesta, JM Guisáun Biotechnology and bioengineering 39 (1), 75-84, 1992 | 52 | 1992 |
The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: implications for RNA recognition F Corzana, I Cuesta, F Freire, J Revuelta, M Torrado, A Bastida, ... Journal of the American Chemical Society 129 (10), 2849-2865, 2007 | 51 | 2007 |
Regioselective enzymatic hydrolysis of acetylated pyranoses and pyranosides using immobilised lipases. An easy chemoenzymatic synthesis of α-and β-D-glucopyranose acetates … M Terreni, R Salvetti, L Linati, R Fernandez-Lafuente, ... Carbohydrate research 337 (18), 1615-1621, 2002 | 50 | 2002 |
Multienzyme system for dihydroxyacetone phosphate-dependent aldolase catalyzed C–C bond formation from dihydroxyacetone I Sánchez-Moreno, JF García-García, A Bastida, E García-Junceda Chemical communications, 1634-1635, 2004 | 48 | 2004 |
Heterologous Over‐expression of α‐1,6‐Fucosyltransferase from Rhizobium sp.: Application to the Synthesis of the Trisaccharide β‐D‐GlcNAc(1→4)‐ [α‐L‐Fuc‐(1→6 … A Bastida, A Fernández‐Mayoralas, R Gómez Arrayás, F Iradier, ... Chemistry–A European Journal 7 (11), 2390-2397, 2001 | 48 | 2001 |
Enzyme stabilization by multipoint covalent attachment to activated pre-existing supports JM Guisán, R Fernández-Lafuente, V Rodríguez, A Bastida, RM Blanco, ... Studies in Organic Chemistry 47, 55-62, 1993 | 46 | 1993 |
From kinase to cyclase: an unusual example of catalytic promiscuity modulated by metal switching I Sánchez‐Moreno, L Iturrate, R Martín‐Hoyos, ML Jimeno, M Mena, ... ChemBioChem 10 (2), 225-229, 2009 | 45 | 2009 |