A marine viral halogenase that iodinates diverse substrates DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ... Nature chemistry 11 (12), 1091-1097, 2019 | 79 | 2019 |
Halogenases: powerful tools for biocatalysis (mechanisms applications and scope) DS Gkotsi, J Dhaliwal, MMW McLachlan, KR Mulholand, RJM Goss Current Opinion in Chemical Biology 43, 119-126, 2018 | 71 | 2018 |
Halogenases: a palette of emerging opportunities for synthetic biology–synthetic chemistry and C–H functionalisation C Crowe, S Molyneux, SV Sharma, Y Zhang, DS Gkotsi, H Connaris, ... Chemical Society Reviews 50 (17), 9443-9481, 2021 | 69 | 2021 |
The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans DRM Smith, T Willemse, DS Gkotsi, W Schepens, BUW Maes, S Ballet, ... Organic letters 16 (10), 2622-2625, 2014 | 67 | 2014 |
Halogenases: structures and functions H Ludewig, S Molyneux, S Ferrinho, K Guo, R Lynch, DS Gkotsi, ... Current Opinion in Structural Biology 65, 51-60, 2020 | 28 | 2020 |
Promiscuous indolyl vinyl isonitrile synthases in the biogenesis and diversification of hapalindole-type alkaloids K Ittiamornkul, Q Zhu, DS Gkotsi, DRM Smith, ML Hillwig, N Nightingale, ... Chemical Science 6 (12), 6836-6840, 2015 | 20 | 2015 |
Nicotiana benthamiana as a Transient Expression Host to Produce Auxin Analogs K Davis, DS Gkotsi, DRM Smith, RJM Goss, L Caputi, SE O’Connor Frontiers in plant science 11, 581675, 2020 | 17 | 2020 |
Biocatalysis in Organic Synthesis. Science of Synthesis, Vol. 1-3. Edited by Kurt Faber, Wolf-Dieter Fessner and Nicholas J. Turner. R Kourist Angewandte Chemie International Edition 54 (43), 2015 | 8 | 2015 |
A marine viral halogenase that iodinates diverse substrates. Nat Chem 11: 1091–1097 DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ... | 7 | 2019 |
Halogenases RJMG S Grüschow, DRM Smith, DS Gkotsi Science of Synthesis: Biocatalysis in Organic Synthesis 3, 313 - 360, 2015 | 7* | 2015 |
PTCHD1 binds cholesterol but not sonic hedgehog, suggesting a distinct cellular function MK Hiltunen, AJ Timmis, M Thomsen, DS Gkotsi, H Iwaï, OM Ribeiro, ... International Journal of Molecular Sciences 24 (3), 2682, 2023 | 3 | 2023 |
Identifying an iodinase C Schnepel, NJ Turner Nature Chemistry 11 (12), 1076-1078, 2019 | 3 | 2019 |
Signaling switching from Hedgehog-GLI to MAPK signaling potentially serves as a compensatory mechanism in melanoma cell lines resistant to GANT-61 N Piteša, M Kurtović, N Bartoniček, DS Gkotsi, J Čonkaš, T Petrić, ... Biomedicines 11 (5), 1353, 2023 | 2 | 2023 |
Discovery and utilisation of wildly different halogenases, powerful new tools for medicinal chemistry RJM Goss, DS Gkotsi UK patent GB1803491 8, 2018 | 2 | 2018 |
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability B Caballero-Ruiz, DS Gkotsi, H Ollerton, CC Morales-Alcala, R Bordone, ... Cancers 15 (2), 369, 2022 | 1 | 2022 |
MODL-07. BUILDING BETTER MODELS OF BRAIN TUMOURS TO ADVANCE PATIENT TREATMENT WITH MINIMAL SIDE EFFECTS DS Gkotsi, I Forder-Denham, TA Ritzmann, J Ramage, ID Kerr, A Jackson, ... Neuro-Oncology 26 (Suppl 4), 0, 2024 | | 2024 |
The Hedgehog receptors PTCH1 and PTCH2 exist as active homomeric and heteromeric complexes AJ Timmis, F Cross, DS Gkotsi, H Ollerton, CA Johnson, NARD Galdo bioRxiv, 2023.08. 08.549832, 2023 | | 2023 |
First Insights into the Characterization of GANT61-Resistant Melanoma Cell Lines N Piteša, M Kurtović, N Bartoniček, DS Gkotsi, J Čonkaš, T Petrić, ... Hedgehog signaling: From molecular structure to dveelopmental biology and …, 2023 | | 2023 |
Iodine goes viral C Deane Nature Chemical Biology 15 (12), 1131-1131, 2019 | | 2019 |
In vivo proton MR spectroscopy of gliomatosis cerebri: Diagnosis and exploration of tumor metabolism ED Gotsis, DS Gkotsi, G Pissakas, I Seimenis Physica Medica 32, 248, 2016 | | 2016 |