DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria LS Shock, PV Thakkar, EJ Peterson, RG Moran, SM Taylor Proceedings of the National Academy of Sciences 108 (9), 3630-3635, 2011 | 581 | 2011 |
Identification of low abundance microbiome in clinical samples using whole genome sequencing C Zhang, K Cleveland, F Schnoll-Sussman, B McClure, M Bigg, P Thakkar, ... Genome biology 16, 1-16, 2015 | 96 | 2015 |
Multicenter, randomized phase II study of neoadjuvant pembrolizumab plus chemotherapy and chemoradiotherapy in esophageal adenocarcinoma (EAC). MA Shah, K Almhanna, S Iqbal, P Thakkar, BJ Schneider, R Yantiss, Y Wu, ... Journal of Clinical Oncology 39 (15_suppl), 4005-4005, 2021 | 27 | 2021 |
Microtubule engagement with taxane is altered in taxane-resistant gastric cancer G Galletti, C Zhang, A Gjyrezi, K Cleveland, J Zhang, S Powell, ... Clinical Cancer Research 26 (14), 3771-3783, 2020 | 25 | 2020 |
Impact of antibiotic use on response to treatment with immune checkpoint inhibitors. U Khan, C Peña, J Brouwer, K Hoffman, AR Choudhury, C Zhang, ... Journal of Clinical Oncology 37 (4_suppl), 143-143, 2019 | 14 | 2019 |
Multicenter phase II study of cabazitaxel in advanced gastroesophageal cancer: association of HER2 expression and M2-Like tumor-associated macrophages with patient outcome MA Shah, P Enzinger, AH Ko, AJ Ocean, PA Philip, PV Thakkar, ... Clinical Cancer Research 26 (18), 4756-4766, 2020 | 11 | 2020 |
A comparison of homogenization vs. enzymatic lysis for microbiome profiling in clinical endoscopic biopsy tissue samples C Zhang, PV Thakkar, SE Powell, P Sharma, S Vennelaganti, D Betel, ... Frontiers in Microbiology 9, 3246, 2019 | 11 | 2019 |
CLIP-170S is a microtubule+ TIP variant that confers resistance to taxanes by impairing drug-target engagement PV Thakkar, K Kita, U Del Castillo, G Galletti, N Madhukar, EV Navarro, ... Developmental cell 56 (23), 3264-3275. e7, 2021 | 6 | 2021 |
Understanding associations among local microbiome, immune response, and efficacy of immunotherapy in esophageal cancer C Zhang, PV Thakkar, P Sharma, S Vennelaganti, D Betel, MA Shah Cancer Research 79 (13_Supplement), 2826-2826, 2019 | 3 | 2019 |
Cediranib reverses taxane resistance in CLIP-170S expressing gastric cancer WG Stone, U Castillo, PV Thakkar, MA Shah, P Giannakakou Cancer Research 83 (7_Supplement), 1742-1742, 2023 | 1 | 2023 |
Imatinib overrides taxane resistance by selective inhibition of novel CLIP1 variant obstructing the microtubule pore K Kita, PV Thakkar, G Galletti, N Madhukar, EV Navarro, I Barasoain, ... bioRxiv, 838334, 2019 | 1 | 2019 |
Abstract B39: Understanding the association of gut microbiota and tumor microenvironment in gastric and esophageal cancer PV Thakkar, C Zhang, P Sharma, S Vennelaganti, D Betel, MA Shah Cancer Immunology Research 6 (9_Supplement), B39-B39, 2018 | 1 | 2018 |
Understanding the association of gut microbiota and tumor microenvironment in gastric and esophageal cancer PV Thakkar, C Zhang, P Sharma, S Vennelaganti, D Betel, MA Shah Cancer Research 78 (13_Supplement), 5128-5128, 2018 | 1 | 2018 |
Elucidation of mechanisms generating 5-hydroxymethylcytosine (5hmC) in mammalian mitochondria PV Thakkar Virginia Commonwealth University, 2013 | 1 | 2013 |
A novel mitochondrial isoform of mammalian DNA methyltransferase 1 LM Shock, PV Thakkar, EJ Peterson, RG Moran, SM Taylor Cancer Research 70 (8_Supplement), 4803-4803, 2010 | 1 | 2010 |
Gastric Cancer Tumor Immune Microenvironment Landscape: Clinical Implications for Patient Outcome and Response to PD-1 Immune Checkpoint Blockade M Shah, S Sarkar, D Melikhova, P Thakkar, O Kudryashova, N Shin, ... | | 2024 |
Immunoblot Analysis from Single Cells Using Milo™ Single-Cell Western Platform PV Thakkar Single Cell Analysis: Methods and Protocols, 201-214, 2024 | | 2024 |
Variants of CLIP-170 associated with taxane resistance in tumors PV Thakkar, K Kita, U del Castillo, WG Stone, G Galletti, N Madhukar, ... Cancer Research 82 (12_Supplement), 2623-2623, 2022 | | 2022 |
Tumor immune microenvironment based molecular functional clustering reveals a prognostic signature that predicts overall survival in patients with gastric cancer PV Thakkar, O Kudryashova, D Melikhova, N Samarina, S Degryse, ... Cancer Research 81 (13_Supplement), 3182-3182, 2021 | | 2021 |
Systems biology identifies Gleevec as a specific inhibitor of CLIP-170S, a novel+ TIP isoform, which causes taxane resistance in cancer cells and patients by obstructing the … PV Thakkar, K Kita, G Galletti, N Madhukar, EV Navarro, K Cleveland, ... Cancer Research 80 (16_Supplement), 641-641, 2020 | | 2020 |