Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype AJ Freemerman, AR Johnson, GN Sacks, JJ Milner, EL Kirk, MA Troester, ... Journal of Biological Chemistry 289 (11), 7884-7896, 2014 | 904 | 2014 |
The inflammation highway: metabolism accelerates inflammatory traffic in obesity AR Johnson, J Justin Milner, L Makowski Immunological reviews 249 (1), 218-238, 2012 | 733 | 2012 |
Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours JJ Milner, C Toma, B Yu, K Zhang, K Omilusik, AT Phan, D Wang, ... Nature 552 (7684), 253-257, 2017 | 600 | 2017 |
The impact of obesity on the immune response to infection JJ Milner, MA Beck Proceedings of the Nutrition Society 71 (2), 298-306, 2012 | 535 | 2012 |
Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation B Yu, K Zhang, JJ Milner, C Toma, R Chen, JP Scott-Browne, RM Pereira, ... Nature immunology 18 (5), 573-582, 2017 | 237 | 2017 |
Heterogenous populations of tissue-resident CD8+ T cells are generated in response to infection and malignancy JJ Milner, C Toma, Z He, NS Kurd, QP Nguyen, B McDonald, L Quezada, ... Immunity 52 (5), 808-824. e7, 2020 | 207 | 2020 |
Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing NS Kurd, Z He, TL Louis, JJ Milner, KD Omilusik, W Jin, MS Tsai, ... Science immunology 5 (47), eaaz6894, 2020 | 174 | 2020 |
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses BS Boland, Z He, MS Tsai, JG Olvera, KD Omilusik, HG Duong, ES Kim, ... Science immunology 5 (50), eabb4432, 2020 | 173 | 2020 |
The transcription factor Runx3 establishes chromatin accessibility of cis-regulatory landscapes that drive memory cytotoxic T lymphocyte formation D Wang, H Diao, AJ Getzler, W Rogal, MA Frederick, J Milner, B Yu, ... Immunity 48 (4), 659-674. e6, 2018 | 170 | 2018 |
Obesity increases mortality and modulates the lung metabolome during pandemic H1N1 influenza virus infection in mice JJ Milner, J Rebeles, S Dhungana, DA Stewart, SCJ Sumner, MH Meyers, ... The Journal of Immunology 194 (10), 4846-4859, 2015 | 163 | 2015 |
B cell activity is impaired in human and mouse obesity and is responsive to an essential fatty acid upon murine influenza infection R Kosaraju, W Guesdon, MJ Crouch, HL Teague, E Sullivan, EA Karlsson, ... The Journal of Immunology 198 (12), 4738-4752, 2017 | 148 | 2017 |
Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments JT Crowl, M Heeg, A Ferry, JJ Milner, KD Omilusik, C Toma, Z He, ... Nature immunology 23 (7), 1121-1131, 2022 | 129 | 2022 |
Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation AR Johnson, Y Qin, AJ Cozzo, AJ Freemerman, MJ Huang, L Zhao, ... Molecular metabolism 5 (7), 506-526, 2016 | 121 | 2016 |
Myeloid Slc2a1-deficient murine model revealed macrophage activation and metabolic phenotype are fueled by GLUT1 AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, ... The Journal of Immunology 202 (4), 1265-1286, 2019 | 120 | 2019 |
Transcriptional programming of tissue-resident memory CD8+ T cells JJ Milner, AW Goldrath Current opinion in immunology 51, 162-169, 2018 | 120 | 2018 |
Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population JJ Milner, H Nguyen, K Omilusik, M Reina-Campos, M Tsai, C Toma, ... Proceedings of the National Academy of Sciences 117 (41), 25667-25678, 2020 | 100 | 2020 |
Diet-induced obese mice exhibit altered heterologous immunity during a secondary 2009 pandemic H1N1 infection JJ Milner, PA Sheridan, EA Karlsson, S Schultz-Cherry, Q Shi, MA Beck The Journal of Immunology 191 (5), 2474-2485, 2013 | 97 | 2013 |
Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells KD Omilusik, MS Nadjsombati, LA Shaw, B Yu, JJ Milner, AW Goldrath Journal of Experimental Medicine 215 (3), 773-783, 2018 | 88 | 2018 |
Role of HGF in obesity-associated tumorigenesis: C3(1)-TAg mice as a model for human basal-like breast cancer S Sundaram, AJ Freemerman, AR Johnson, JJ Milner, KK McNaughton, ... Breast cancer research and treatment 142, 489-503, 2013 | 51 | 2013 |
Tissue factor deficiency increases alveolar hemorrhage and death in influenza A virus‐infected mice S Antoniak, K Tatsumi, Y Hisada, JJ Milner, SD Neidich, CM Shaver, ... Journal of Thrombosis and Haemostasis 14 (6), 1238-1248, 2016 | 48 | 2016 |