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Terrence Tsz-Tai Yuen
Terrence Tsz-Tai Yuen
The Department of Microbiology, The Univeristy of Hong Kong
Verified email at hku.hk
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Year
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2
L Liu, S Iketani, Y Guo, JFW Chan, M Wang, L Liu, Y Luo, H Chu, Y Huang, ...
Nature 602 (7898), 676-681, 2022
12192022
Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory …
H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan, Y Wang, B Hu, CCY Yip, ...
The Lancet Microbe 1 (1), e14-e23, 2020
8762020
Antibody evasion properties of SARS-CoV-2 Omicron sublineages
S Iketani, L Liu, Y Guo, L Liu, JFW Chan, Y Huang, M Wang, Y Luo, J Yu, ...
Nature 604 (7906), 553-556, 2022
7952022
Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19
H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, Y Hou, H Shuai, D Yang, ...
Clinical Infectious Diseases 71 (6), 1400-1409, 2020
7422020
Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron
H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin, X Huang, C Yoon, ...
Nature 603 (7902), 693-699, 2022
5712022
Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation
D Yang, H Chu, Y Hou, Y Chai, H Shuai, ACY Lee, X Zhang, Y Wang, ...
The Journal of infectious diseases 222 (5), 734-745, 2020
1982020
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters
S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VK Man Poon, ...
Science 377 (6604), 428-433, 2022
1492022
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung
H Chu, B Hu, X Huang, Y Chai, D Zhou, Y Wang, H Shuai, D Yang, Y Hou, ...
Nature communications 12 (1), 134, 2021
1382021
Emerging SARS-CoV-2 variants expand species tropism to murines
H Shuai, JFW Chan, TTT Yuen, C Yoon, JC Hu, L Wen, B Hu, D Yang, ...
EBioMedicine 73, 2021
1302021
An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron
BX Quan, H Shuai, AJ Xia, Y Hou, R Zeng, XL Liu, GF Lin, JX Qiao, WP Li, ...
Nature Microbiology 7 (5), 716-725, 2022
792022
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA. 1 and BA. 2
B Hu, JFW Chan, H Liu, Y Liu, Y Chai, J Shi, H Shuai, Y Hou, X Huang, ...
Emerging microbes & infections 11 (1), 2275-2287, 2022
622022
Coronaviruses exploit a host cysteine-aspartic protease for replication
H Chu, Y Hou, D Yang, L Wen, H Shuai, C Yoon, J Shi, Y Chai, TTT Yuen, ...
Nature 609 (7928), 785-792, 2022
552022
SARS-CoV-2 induces a more robust innate immune response and replicates less efficiently than SARS-CoV in the human intestines: an ex vivo study with implications on …
H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, H Shuai, D Yang, B Hu, ...
Cellular and molecular gastroenterology and hepatology 11 (3), 771-781, 2021
492021
Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2
L Huang, TTT Yuen, Z Ye, S Liu, G Zhang, H Chu, J Yue
Signal Transduction and Targeted Therapy 6 (1), 168, 2021
432021
SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
W Qiao, HE Lau, H Xie, VKM Poon, CCS Chan, H Chu, S Yuan, TTT Yuen, ...
Nature communications 13 (1), 2539, 2022
402022
Bacillus Calmette-Guérin–induced trained immunity protects against SARS-CoV-2 challenge in K18-hACE2 mice
BZ Zhang, H Shuai, HR Gong, JC Hu, B Yan, TTT Yuen, YF Hu, C Yoon, ...
JCI insight 7 (11), 2022
392022
A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo
JFW Chan, YJ Oh, S Yuan, H Chu, ML Yeung, D Canena, CCS Chan, ...
Cell Reports Medicine 3 (10), 2022
302022
Virological features and pathogenicity of SARS-CoV-2 Omicron BA. 2
JFW Chan, B Hu, Y Chai, H Shuai, H Liu, J Shi, Y Liu, C Yoon, J Zhang, ...
Cell Reports Medicine 3 (9), 2022
302022
The SARS-CoV-2 Omicron (B. 1.1. 529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model
S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VKM Poon, ...
BioRxiv, 2022.01. 12.476031, 2022
242022
The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA. 1, BA. 2, and BA. 5
H Shuai, JFW Chan, B Hu, Y Chai, C Yoon, H Liu, Y Liu, J Shi, T Zhu, ...
EBioMedicine 95, 2023
232023
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