The stereoselective synthesis of. alpha.-amino acids by phase-transfer catalysis MJ O'Donnell, WD Bennett, S Wu Journal of the American Chemical Society 111 (6), 2353-2355, 1989 | 792 | 1989 |
Complex induced proximity effects: enantioselective syntheses based on asymmetric deprotonations of N-Boc-pyrrolidines P Beak, ST Kerrick, S Wu, J Chu Journal of the American Chemical Society 116 (8), 3231-3239, 1994 | 446 | 1994 |
A new active catalyst species for enantioselective alkylation by phase-transfer catalysis MJ O'Donnell, S Wu, JC Huffman Tetrahedron 50 (15), 4507-4518, 1994 | 339 | 1994 |
T4 report: Toward good read-across practice (GRAP) guidance N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ... Altex 33 (2), 149, 2016 | 198 | 2016 |
Asymmetric Deprotonation by BuLi/(−)-Sparteine: Convenient and Highly Enantioselective Syntheses of (S)-2-Aryl-Boc-Pyrrolidines S Wu, S Lee, P Beak Journal of the American Chemical Society 118 (4), 715-721, 1996 | 174 | 1996 |
A catalytic enantioselective synthesis of α-methyl amino acid derivatives by phase-transfer catalysis MJ O'Donnell, S Wu Tetrahedron: Asymmetry 3 (5), 591-594, 1992 | 173 | 1992 |
A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments S Wu, K Blackburn, J Amburgey, J Jaworska, T Federle Regulatory Toxicology and Pharmacology 56 (1), 67-81, 2010 | 167 | 2010 |
Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants S Wu, J Fisher, J Naciff, M Laufersweiler, C Lester, G Daston, K Blackburn Chemical Research in Toxicology 26 (12), 1840-1861, 2013 | 158 | 2013 |
Chiral organolithium complexes: The effect of ligand structure on the enantioselective deprotonation of Boc-pyrrolidine DJ Gallagher, S Wu, NA Nikolic, P Beak The Journal of Organic Chemistry 60 (25), 8148-8154, 1995 | 143 | 1995 |
Design and synthesis of a series of novel pyrazolopyridines as HIF 1-α prolyl hydroxylase inhibitors NC Warshakoon, S Wu, A Boyer, R Kawamoto, S Renock, K Xu, ... Bioorganic & medicinal chemistry letters 16 (21), 5687-5690, 2006 | 110 | 2006 |
t4 report: Supporting read-across using biological data H Zhu, M Bouhifd, N Kleinstreuer, ED Kroese, Z Liu, T Luechtefeld, ... Altex 33 (2), 167, 2016 | 103 | 2016 |
A novel series of imidazo [1, 2-a] pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors NC Warshakoon, S Wu, A Boyer, R Kawamoto, J Sheville, S Renock, K Xu, ... Bioorganic & medicinal chemistry letters 16 (21), 5598-5601, 2006 | 92 | 2006 |
Intramolecular Cyclizations of. Alpha.-Lithioamine Synthetic Equivalents: Convenient Syntheses of 3-, 5-, and 6-Membered-Ring Heterocyclic Nitrogen Compounds and Elaborations … P Beak, S Wu, EK Yum, YM Jun The Journal of Organic Chemistry 59 (2), 276-277, 1994 | 89 | 1994 |
Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1α prolyl hydroxylase inhibitors NC Warshakoon, S Wu, A Boyer, R Kawamoto, J Sheville, S Renock, K Xu, ... Bioorganic & Medicinal Chemistry Letters 16 (21), 5517-5522, 2006 | 84 | 2006 |
Prolyl hydroxylase inhibitors and methods of use RM Kawamoto, S Wu, NC Warshakoon, AG Evdokimov, KD Greis, ... US Patent 7,811,595, 2010 | 73 | 2010 |
Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1. 5 blockers S Wu, A Fluxe, J Sheffer, JM Janusz, BE Blass, R White, C Jackson, ... Bioorganic & medicinal chemistry letters 16 (24), 6213-6218, 2006 | 64 | 2006 |
Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological … K Blackburn, D Bjerke, G Daston, S Felter, C Mahony, J Naciff, S Robison, ... Regulatory Toxicology and Pharmacology 60 (1), 120-135, 2011 | 61 | 2011 |
Evolution of thiazolidine-based blockers of human Kv1. 5 for the treatment of atrial arrhythmias CM Jackson, B Blass, K Coburn, L Djandjighian, G Fadayel, AJ Fluxe, ... Bioorganic & Medicinal Chemistry Letters 17 (1), 282-284, 2007 | 53 | 2007 |
Design and synthesis of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors NC Warshakoon, S Wu, A Boyer, R Kawamoto, J Sheville, RT Bhatt, ... Bioorganic & medicinal chemistry letters 16 (21), 5616-5620, 2006 | 50 | 2006 |
Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis MJ O'donnell, S Wu, I Esikova, A Mi US Patent 5,554,753, 1996 | 44 | 1996 |