Regulation of airway smooth muscle contraction in health and disease M Lam, E Lamanna, JE Bourke Smooth muscle spontaneous activity: Physiological and pathological …, 2019 | 62 | 2019 |
Airway remodeling and hyperreactivity in a model of bronchopulmonary dysplasia and their modulation by IL-1 receptor antagonist SG Royce, MF Nold, C Bui, C Donovan, M Lam, E Lamanna, I Rudloff, ... American Journal of Respiratory Cell and Molecular Biology 55 (6), 858-868, 2016 | 48 | 2016 |
Serelaxin as a novel therapeutic opposing fibrosis and contraction in lung diseases M Lam, SG Royce, CS Samuel, JE Bourke Pharmacology & therapeutics 187, 61-70, 2018 | 30 | 2018 |
Serelaxin elicits bronchodilation and enhances β-adrenoceptor-mediated airway relaxation M Lam, SG Royce, C Donovan, M Jelinic, LJ Parry, CS Samuel, ... Frontiers in Pharmacology 7, 406, 2016 | 23 | 2016 |
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease A Chakraborty, AA Pinar, M Lam, JE Bourke, SG Royce, C Selomulya, ... Biomaterials 273, 120796, 2021 | 21 | 2021 |
RAGE and TLR4 differentially regulate airway hyperresponsiveness: Implications for COPD VSRR Allam, A Faiz, M Lam, SNH Rathnayake, B Ditz, SD Pouwels, ... Allergy 76 (4), 1123-1135, 2021 | 20 | 2021 |
Another one fights the dust: targeting the NLRP3 inflammasome for the treatment of silicosis M Lam, A Mansell, MD Tate American journal of respiratory cell and molecular biology 66 (6), 601-611, 2022 | 19 | 2022 |
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases CAH Docherty, AJ Fernando, S Rosli, M Lam, RE Dolle, MA Navia, ... Clinical & Translational Immunology 12 (6), e1455, 2023 | 13 | 2023 |
Perspectives on precision cut lung slices—powerful tools for investigation of mechanisms and therapeutic targets in lung diseases M Lam, E Lamanna, L Organ, C Donovan, JE Bourke Frontiers in pharmacology 14, 1162889, 2023 | 11 | 2023 |
A new pathway to airway relaxation: targeting the “other” cyclase in asthma M Lam, JE Bourke American Journal of Respiratory Cell and Molecular Biology 62 (1), 3-4, 2020 | 10 | 2020 |
Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia Y Miura, M Lam, JE Bourke, S Kanazawa Life Science Alliance 5 (1), 2022 | 9 | 2022 |
Solving the riddle: targeting the imbalance of sphingolipids in asthma to oppose airway hyperresponsiveness M Lam, JE Bourke American Journal of Respiratory Cell and Molecular Biology 63 (5), 555-557, 2020 | 9 | 2020 |
Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection S Rosli, CM Harpur, M Lam, AC West, C Hodges, A Mansell, KE Lawlor, ... Cell Death & Disease 14 (11), 727, 2023 | 8 | 2023 |
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection CM Harpur, AC West, MA Le Page, M Lam, C Hodges, O Oseghale, ... Clinical & Translational Immunology 12 (3), e1443, 2023 | 7 | 2023 |
Small airway hyperresponsiveness is associated with impaired alveolar development in a mouse model of bronchopulmonary dysplasia J Bourke, M Lam, S Royce, M Nold, C Nold European Respiratory Journal 46 (suppl 59), 2015 | 4 | 2015 |
Beyond TGFβ1-novel treatment strategies targeting lung fibrosis C Sim, E Lamanna, F Cirnigliaro, M Lam The International Journal of Biochemistry & Cell Biology 141, 106090, 2021 | 2 | 2021 |
Biased negative allosteric modulators of the calcium-sensing receptor differentially oppose airway contraction in mouse precision cut lung slices J Diao, M Lam, K Gregory, K Leach, JE Bourke TP118. TP118 AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA, A4516-A4516, 2021 | 2 | 2021 |
The calcium-sensing receptor CaSR mediates airway contraction in a house dust mite model of allergic airway disease J Bourke, J Diao, M Lam, C Maksdi, K Gregory, K Leach European Respiratory Journal 54 (suppl 63), 2019 | 2 | 2019 |
Free fatty acid receptors, FFAR1 and FFAR4, are novel bronchodilator targets in mouse and human precision-cut lung slices J Bourke, R Angeles, C Donovan, M Lam, J Micallef, B Shimpukade, ... European Respiratory Journal 52 (suppl 62), 2018 | 2 | 2018 |
Serelaxin is a novel bronchodilator which enhances β-adrenoceptor-mediated airway relaxation in multiple species JE Bourke, S Royce, C Samuel, M Lam A29. NOVEL MECHANISMS FOR AIRWAY SMOOTH MUSCLE CONTRACTION AND RELAXATION …, 2018 | 2 | 2018 |