Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress JRAJ Moonen, ES Lee, M Schmidt, M Maleszewska, JA Koerts, ... Cardiovascular research 108 (3), 377-386, 2015 | 245 | 2015 |
In pulmonary arterial hypertension, reduced BMPR2 promotes endothelial-to-mesenchymal transition via HMGA1 and its target slug RK Hopper, JRAJ Moonen, I Diebold, A Cao, CJ Rhodes, NF Tojais, ... Circulation 133 (18), 1783-1794, 2016 | 227 | 2016 |
IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner M Maleszewska, JRAJ Moonen, N Huijkman, B van de Sluis, G Krenning, ... Immunobiology 218 (4), 443-454, 2013 | 224 | 2013 |
Endothelial progenitor cells give rise to pro-angiogenic smooth muscle-like progeny JRAJ Moonen, G Krenning, MGL Brinker, JA Koerts, MJA Van Luyn, ... Cardiovascular research 86 (3), 506-515, 2010 | 188 | 2010 |
Intrinsic endocardial defects contribute to hypoplastic left heart syndrome Y Miao, L Tian, M Martin, SL Paige, FX Galdos, J Li, A Klein, H Zhang, ... Cell stem cell 27 (4), 574-589. e8, 2020 | 126 | 2020 |
FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-β signaling ACP Correia, JRAJ Moonen, MGL Brinker, G Krenning Journal of cell science 129 (3), 569-579, 2016 | 118 | 2016 |
Vascular smooth muscle cells for use in vascular tissue engineering obtained by endothelial-to-mesenchymal transdifferentiation (EnMT) on collagen matrices G Krenning, JRAJ Moonen, MJA van Luyn, MC Harmsen Biomaterials 29 (27), 3703-3711, 2008 | 116 | 2008 |
Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus JRAJ Moonen, K de Leeuw, XJGY van Seijen, CGM Kallenberg, ... Arthritis research & therapy 9 (4), R84, 2007 | 98 | 2007 |
Cellular senescence impairs the reversibility of pulmonary arterial hypertension DE Van Der Feen, GPL Bossers, QAJ Hagdorn, JR Moonen, K Kurakula, ... Science Translational Medicine 12 (554), eaaw4974, 2020 | 91 | 2020 |
Endothelial plasticity: shifting phenotypes through force feedback G Krenning, VG Barauna, JE Krieger, MC Harmsen, JRAJ Moonen Stem cells international 2016 (1), 9762959, 2016 | 87 | 2016 |
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy N Sayed, C Liu, M Ameen, F Himmati, JZ Zhang, S Khanamiri, JR Moonen, ... Science translational medicine 12 (554), eaax9276, 2020 | 69 | 2020 |
Erk5 inhibits endothelial migration via KLF2-dependent down-regulation of PAK1 RK Komaravolu, C Adam, JRAJ Moonen, MC Harmsen, M Goebeler, ... Cardiovascular research 105 (1), 86-95, 2015 | 60 | 2015 |
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ... Circulation 136 (20), 1920-1935, 2017 | 59 | 2017 |
ALDH1A3 coordinates metabolism with gene regulation in pulmonary arterial hypertension D Li, NY Shao, JR Moonen, Z Zhao, M Shi, S Otsuki, L Wang, T Nguyen, ... Circulation 143 (21), 2074-2090, 2021 | 57 | 2021 |
PPARγ-p53-mediated vasculoregenerative program to reverse pulmonary hypertension JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ... Circulation research 128 (3), 401-418, 2021 | 57 | 2021 |
The flow dependency of Tie2 expression in endotoxemia NF Kurniati, RM Jongman, F Vom Hagen, KC Spokes, J Moser, ER Regan, ... Intensive care medicine 39, 1262-1271, 2013 | 57 | 2013 |
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress JR Moonen, J Chappell, M Shi, T Shinohara, D Li, MR Mumbach, F Zhang, ... Nature communications 13 (1), 4941, 2022 | 42 | 2022 |
Pleiotropism of adiponectin: inflammation, neovascularization, and fibrosis G Krenning, JRAJ Moonen, MC Harmsen Circulation research 104 (9), 1029-1031, 2009 | 39 | 2009 |
MicroRNA‐374b induces endothelial‐to‐mesenchymal transition and early lesion formation through the inhibition of MAPK7 signaling B Vanchin, E Offringa, J Friedrich, MGL Brinker, B Kiers, AC Pereira, ... The Journal of pathology 247 (4), 456-470, 2019 | 35 | 2019 |
Generating new blood flow: integrating developmental biology and tissue engineering G Krenning, JRAJ Moonen, MJA van Luyn, MC Harmsen Trends in cardiovascular medicine 18 (8), 312-323, 2008 | 34 | 2008 |